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Virtual Patients Using Large Language Models: Scalable, Contextualized Simulation of Clinician-Patient Dialogue With Feedback

Virtual Patients Using Large Language Models: Scalable, Contextualized Simulation of Clinician-Patient Dialogue With Feedback

We iteratively and rigorously engineered detailed “prompts” guiding GPT to emulate a diagnosis-focused or management-focused VP and provide feedback. To instantiate a specific VP, the interface accesses a 1-page case description. Narrative S1 in Multimedia Appendix 1 reports the full prompt and 1 case description. We selected as topics 2 common problems in ambulatory medicine: chronic cough (a diagnostic task) and diabetes (a management task).

David A Cook, Joshua Overgaard, V Shane Pankratz, Guilherme Del Fiol, Chris A Aakre

J Med Internet Res 2025;27:e68486

Environmental Impact of Physical Visits and Telemedicine in Nursing Care at Home: Comparative Life Cycle Assessment

Environmental Impact of Physical Visits and Telemedicine in Nursing Care at Home: Comparative Life Cycle Assessment

Telemedicine is often considered to be a promising solution for sustainable health care delivery as multiple reviews reported a reduction in travel-related emissions [9,10]. Savings were typically setting dependent and ranged anywhere between 0.7 and 372 kg of carbon dioxide equivalents (kg CO2eq) per consultation [10].

Egid M van Bree, Lynn E Snijder, Hans C Ossebaard, Evelyn A Brakema

J Med Internet Res 2025;27:e67538

Identifying Patient-Reported Outcome Measure Documentation in Veterans Health Administration Chiropractic Clinic Notes: Natural Language Processing Analysis

Identifying Patient-Reported Outcome Measure Documentation in Veterans Health Administration Chiropractic Clinic Notes: Natural Language Processing Analysis

Multiple notes can be written to describe the same identified chiropractic visit; for example, a resident chiropractor note and an attending chiropractor note may each contain data relevant to a single visit. We concatenated all notes linked to the same unique visit identifier on the same date of service (regardless of note author) to create a 1-to-1 relationship between visits and clinic notes. A unique character set was used as a delimiter to separate individual notes.

Brian C Coleman, Kelsey L Corcoran, Cynthia A Brandt, Joseph L Goulet, Stephen L Luther, Anthony J Lisi

JMIR Med Inform 2025;13:e66466

Digital Ergonomics of NavegApp, a Novel Serious Game for Spatial Cognition Assessment: Content Validity and Usability Study

Digital Ergonomics of NavegApp, a Novel Serious Game for Spatial Cognition Assessment: Content Validity and Usability Study

SC involves a range of cognitive functions, including the perception, organization, and use of location and object–based information to understand and navigate through physical or mental spaces [12-14]. When integrated, these processes facilitate complex spatial behaviors, such as solving mazes or tracing routes from point A to point B using landmarks or self-positioning as a reference [13].

Juan Pablo Sanchez-Escudero, David Aguillon, Stella Valencia, Mauricio A Garcia-Barrera, Daniel Camilo Aguirre-Acevedo, Natalia Trujillo

JMIR Serious Games 2025;13:e66167

Digital Health Resilience and Well-Being Interventions for Military Members, Veterans, and Public Safety Personnel: Environmental Scan and Quality Review

Digital Health Resilience and Well-Being Interventions for Military Members, Veterans, and Public Safety Personnel: Environmental Scan and Quality Review

Each DMHI was evaluated based on 2 quality rating scales: the A-MARS and the ARIA. A description of each is provided in the subsequent sections. The A-MARS [33] is a rating scale adapted from the MARS [34] and was used to review RBs and WBPs. The A-MARS was developed to evaluate health-related e-tools, with a specific expansion of the engagement subscale.

Rashell R Allen, Myrah A Malik, Carley Aquin, Lucijana Herceg, Suzette Brémault-Phillips, Phillip R Sevigny

JMIR Mhealth Uhealth 2025;13:e64098

Accelerometry-Assessed Physical Activity and Circadian Rhythm to Detect Clinical Disability Status in Multiple Sclerosis: Cross-Sectional Study

Accelerometry-Assessed Physical Activity and Circadian Rhythm to Detect Clinical Disability Status in Multiple Sclerosis: Cross-Sectional Study

The EDSS, however, is semiquantitative, has limited reliability, and only captures a person’s state at one short point in time during a clinical visit [1]. People with MS may have different disability states at different times throughout the day, as symptoms can fluctuate with temperature, fatigue, stress, and other factors [2,3].

Nicole Bou Rjeily, Muraleetharan Sanjayan, Pratim Guha Niyogi, Blake E Dewey, Alexandra Zambriczki Lee, Christy Hulett, Gabriella Dagher, Chen Hu, Rafal D Mazur, Elena M Kenney, Erin Brennan, Anna DuVal, Peter A Calabresi, Vadim Zipunnikov, Kathryn C Fitzgerald, Ellen M Mowry

JMIR Mhealth Uhealth 2025;13:e57599

Effectiveness of the Safe Step Digital Exercise Program to Prevent Falls in Older Community-Dwelling Adults: Randomized Controlled Trial

Effectiveness of the Safe Step Digital Exercise Program to Prevent Falls in Older Community-Dwelling Adults: Randomized Controlled Trial

Inclusion criteria were (1) participants aged 70 years or older, (2) having fallen or experienced a decline in perceived postural balance during the past year, (3) having access to a smartphone or tablet and using it regularly, (4) having own email address and using it, (5) being able to understand verbal and written instructions in Swedish, (6) being able to rise from a standard height chair without a person helping, and (7) being able to walk independently without a walking aid indoors.

Beatrice Pettersson, Lillemor Lundin-Olsson, Dawn A Skelton, Per Liv, Magnus Zingmark, Erik Rosendahl, Marlene Sandlund

J Med Internet Res 2025;27:e67539

Examining Quality of Work Life in Atlantic Canadian Long-Term Care Homes: Protocol for a Cross-Sectional Survey Study

Examining Quality of Work Life in Atlantic Canadian Long-Term Care Homes: Protocol for a Cross-Sectional Survey Study

Additionally, according to the 2021 census, between 96% to 99% of the population in Nova Scotia, Prince Edward Island, Newfoundland and Labrador spoke English as a first language, and as a bilingual province, nearly 70% of the New Brunswick population spoke English as a first language while the remaining 30% spoke French [9].

Janice M Keefe, Rose McCloskey, Marilyn J Hodgins, Caitlin McArthur, Adrian MacKenzie, Lori E Weeks, Carole A Estabrooks

JMIR Res Protoc 2025;14:e66338

Mental Health Professionals’ Technology Usage and Attitudes Toward Digital Health for Psychosis: Comparative Cross-Sectional Survey Study

Mental Health Professionals’ Technology Usage and Attitudes Toward Digital Health for Psychosis: Comparative Cross-Sectional Survey Study

Characteristics of survey participants. a Not available. Participants from survey 2 had a median age of 40 (IQR 31‐50) years and a median time working of 4 (IQR 1.5‐10) years in their current role. Most responders were female (244/352, 69.32%) and White (276/352, 78.41%). Around a third held a university bachelor’s degree (129/352, 36.65%), worked in a community mental health team (119/352, 33.81%), and practiced as a mental health nurse (99/352, 28.12%).

Xiaolong Zhang, Natalie Berry, Daniela Di Basilio, Cara Richardson, Emily Eisner, Sandra Bucci

JMIR Ment Health 2025;12:e68362

Breast Cancer Vlogs on YouTube: Descriptive and Content Analyses

Breast Cancer Vlogs on YouTube: Descriptive and Content Analyses

A popular subset of vlogs are created by women with breast cancer, in which they document their breast cancer experiences in a publicly accessible digital format. As videos that tend to invite viewers into the lives of their creators, vlogs typically receive high levels of engagement and draw audiences who will continue watching in order to keep up with what creators are doing next.

Nina Morena, Elly Dimya Htite, Yitzchok Ahisar, Victoria Hayman, Carrie A Rentschler, Ari N Meguerditchian

JMIR Infodemiology 2025;5:e66812