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The PMIS (Pearson r=−0.76; P
As we examined the sensitivity and specificity data to choose cut scores, we chose to favor sensitivity to minimize missing individuals with true disease in this sample of patients considered high risk because of their cognitive concerns. The cut scores for a positive result on the 5-Cog components were as follows: PMIS ≤6 (range 0-8), Symbol Match ≤25 (range 0-65), and s MCR >5 (range 0-7).
JMIR Res Protoc 2025;14:e60471
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For example, assume a field “Sex” is provided with the value “M,” and this has previously been manually mapped to the OMOP concept 8507 “Male” in one scan R=report. In the case where a later scan report is uploaded with another field “Gender” and the value “M,” the system automatically applies the previous mapping rule to this value in this field in the new scan report.
JMIR Res Protoc 2025;14:e60917
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The application of this mapping to the data was performed using R version 4.3.2 (R Foundation for Statistical Computing). The full list of diagnosis names corresponding to ADRD diagnosis categories is provided in Multimedia Appendix 1.
To assess associations between clusters and sex, as well as ADRD diagnoses, we used the chi-square test.
JMIR Aging 2025;8:e65178
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The visualization procedures were conducted via the “qgraph” package in R (R Core Team) [34]. To enhance visual clarity, we adjusted the scaling of edge widths and color saturation using the cut argument. The improved visual representation of the network is available (Figure S5 in Multimedia Appendix 1).
We used the “networktools” package [32] to quantify to what extent each compulsivity dimension was related to the PUI symptom cluster and identify influential bridge nodes.
J Med Internet Res 2025;27:e66191
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