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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JRAT</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Rehabil Assist Technol</journal-id>
      <journal-title>JMIR Rehabilitation and Assistive Technologies</journal-title>
      <issn pub-type="epub">2369-2529</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="publisher-id">v8i2e24276</article-id>
      <article-id pub-id-type="pmid">34106086</article-id>
      <article-id pub-id-type="doi">10.2196/24276</article-id>
      <article-categories>
        <subj-group subj-group-type="heading">
          <subject>Original Paper</subject>
        </subj-group>
        <subj-group subj-group-type="article-type">
          <subject>Original Paper</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Feasibility of an Internet-Based Intervention to Promote Exercise for People With Spinal Cord Injury: Observational Pilot Study</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="editor">
          <name>
            <surname>Eysenbach</surname>
            <given-names>Gunther</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Bechard</surname>
            <given-names>Lauren</given-names>
          </name>
        </contrib>
        <contrib contrib-type="reviewer">
          <name>
            <surname>Villarino</surname>
            <given-names>Resti Tito</given-names>
          </name>
        </contrib>
      </contrib-group>
      <contrib-group>
        <contrib id="contrib1" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Ochoa</surname>
            <given-names>Christa</given-names>
          </name>
          <degrees>MPH</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-9252-5247</ext-link>
        </contrib>
        <contrib id="contrib2" contrib-type="author" equal-contrib="yes">
          <name name-style="western">
            <surname>Cole</surname>
            <given-names>Maria</given-names>
          </name>
          <degrees>MPH</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0003-3285-0774</ext-link>
        </contrib>
        <contrib id="contrib3" contrib-type="author" corresp="yes" equal-contrib="yes">
          <name name-style="western">
            <surname>Froehlich-Grobe</surname>
            <given-names>Katherine</given-names>
          </name>
          <degrees>PhD</degrees>
          <xref rid="aff1" ref-type="aff">1</xref>
          <xref rid="aff2" ref-type="aff">2</xref>
          <address>
            <institution>Craig Hospital</institution>
            <addr-line>3425 S Clarkson Street</addr-line>
            <addr-line>Englewood, CO, 80113</addr-line>
            <country>United States</country>
            <phone>1 2145317260</phone>
            <email>KFroehlich-Grobe@Craighospital.org</email>
          </address>
          <ext-link ext-link-type="orcid">https://orcid.org/0000-0002-3274-5109</ext-link>
        </contrib>
      </contrib-group>
      <aff id="aff1">
        <label>1</label>
        <institution>Baylor Scott &#38; White Institute for Rehabilitation</institution>
        <institution>Baylor Scott &#38; White Research Institute</institution>
        <institution>Baylor Scott &#38; White Health</institution>
        <addr-line>Dallas, TX</addr-line>
        <country>United States</country>
      </aff>
      <aff id="aff2">
        <label>2</label>
        <institution>Craig Hospital</institution>
        <addr-line>Englewood, CO</addr-line>
        <country>United States</country>
      </aff>
      <author-notes>
        <corresp>Corresponding Author: Katherine Froehlich-Grobe <email>KFroehlich-Grobe@Craighospital.org</email></corresp>
      </author-notes>
      <pub-date pub-type="collection">
        <season>Apr-Jun</season>
        <year>2021</year>
      </pub-date>
      <pub-date pub-type="epub">
        <day>9</day>
        <month>6</month>
        <year>2021</year>
      </pub-date>
      <volume>8</volume>
      <issue>2</issue>
      <elocation-id>e24276</elocation-id>
      <history>
        <date date-type="received">
          <day>11</day>
          <month>9</month>
          <year>2020</year>
        </date>
        <date date-type="rev-request">
          <day>3</day>
          <month>11</month>
          <year>2020</year>
        </date>
        <date date-type="rev-recd">
          <day>29</day>
          <month>3</month>
          <year>2021</year>
        </date>
        <date date-type="accepted">
          <day>13</day>
          <month>4</month>
          <year>2021</year>
        </date>
      </history>
      <copyright-statement>©Christa Ochoa, Maria Cole, Katherine Froehlich-Grobe. Originally published in JMIR Rehabilitation and Assistive Technology (https://rehab.jmir.org), 09.06.2021.</copyright-statement>
      <copyright-year>2021</copyright-year>
      <license license-type="open-access" xlink:href="https://creativecommons.org/licenses/by/4.0/">
        <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Rehabilitation and Assistive Technology, is properly cited. The complete bibliographic information, a link to the original publication on https://rehab.jmir.org/, as well as this copyright and license information must be included.</p>
      </license>
      <self-uri xlink:href="https://rehab.jmir.org/2021/2/e24276" xlink:type="simple"/>
      <abstract>
        <sec sec-type="background">
          <title>Background</title>
          <p>People with spinal cord injury (SCI) are less likely to be physically active and have higher chronic disease risk than those in the general population due to physical and metabolic changes that occur postinjury. Few studies have investigated approaches to promote increased physical activity (PA) for people with SCI despite evidence that they face unique barriers, including lack of accessible transportation and exercise equipment. To address these obstacles, we adapted an evidence-based phone-delivered intervention that promoted increased PA among people with SCI into a web-based platform, titled the Workout on Wheels internet intervention (WOW<italic>ii</italic>). The adapted program provides participants with weekly skill-building information and activities, basic exercise equipment, and ongoing support through weekly group videoconferencing.</p>
        </sec>
        <sec sec-type="objective">
          <title>Objective</title>
          <p>This pilot study was conducted to assess the feasibility of using a web-based and virtual format to deliver the WOW<italic>ii</italic> program in a randomized controlled trial.</p>
        </sec>
        <sec sec-type="methods">
          <title>Methods</title>
          <p>We assessed the feasibility of the web-based program by delivering an abbreviated, 4-week version to 10 participants with SCI. Rates of weekly videoconference attendance, activity completion, and exercise activity as tracked by an arm-based activity monitor were recorded for all participants.</p>
        </sec>
        <sec sec-type="results">
          <title>Results</title>
          <p>Participants averaged 3.3 of 4 (83%) weekly group videoconferences attended, 3.4 of 4 (85%) web-based module activities completed, and 2.3 of 4 (58%) weeks of using the arm-based activity monitor. The majority of the sample (9/10, 90%) synced their arm-based PA monitor at least once, and overall engagement as an average of each component across the 4 weeks was 75%.</p>
        </sec>
        <sec sec-type="conclusions">
          <title>Conclusions</title>
          <p>The intervention had sufficiently high levels of engagement to be used in a full randomized controlled trial to test its effectiveness in improving levels of PA among people with SCI. The knowledge we gained from this pilot study informed improvements that were made in the full randomized controlled trial.</p>
        </sec>
      </abstract>
      <kwd-group>
        <kwd>spinal cord injury</kwd>
        <kwd>lifestyle intervention</kwd>
        <kwd>physical activity</kwd>
        <kwd>health promotion</kwd>
        <kwd>eHealth</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>People living with spinal cord injury (SCI) experience increased risk for obesity, excessive fat mass, abnormal lipid metabolism, and glucose intolerance than the general population [<xref ref-type="bibr" rid="ref1">1</xref>-<xref ref-type="bibr" rid="ref5">5</xref>]. At the same time, people with SCI have lower activity levels by as much as 45% to 66% than those without disability and still lower levels than groups with other disabilities, such as cerebral palsy, leg amputation, and chronic heart failure [<xref ref-type="bibr" rid="ref6">6</xref>,<xref ref-type="bibr" rid="ref7">7</xref>]. Accumulating evidence has demonstrated the positive effects of physical activity (PA) among people with SCI on their fitness, muscle strength, body composition, function, psychological well-being, and quality of life, all of which may mitigate the risk of developing chronic disease in the long term [<xref ref-type="bibr" rid="ref8">8</xref>-<xref ref-type="bibr" rid="ref11">11</xref>]. Evidence supports the need to increase PA levels among people with SCI, while a previous review has demonstrated the lack of effective options to increase PA among this population [<xref ref-type="bibr" rid="ref12">12</xref>].</p>
      <p>People with SCI face unique barriers to PA and exercise, including lack of reliable and accessible transportation, which also limits their ability to use community-based recreation centers [<xref ref-type="bibr" rid="ref13">13</xref>,<xref ref-type="bibr" rid="ref14">14</xref>]. The lack of recreation facilities with accessible equipment and knowledgeable staff who can assist people with mobility impairments reduces options for exercise [<xref ref-type="bibr" rid="ref15">15</xref>]. Other barriers include lack of funds to purchase appropriate exercise equipment or gym memberships, plus low self-efficacy for exercise among people with disabilities [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref16">16</xref>-<xref ref-type="bibr" rid="ref19">19</xref>]. The internet offers a way to overcome these barriers and meet the needs of people with SCI and other disabilities through instant access to information, on demand from the location of their choice, including at home, with the added benefit of connecting with others remotely. Although internet access is lower among those with lower income and racial/ethnic groups, recent US data show that 69.2% of people with traumatic SCI use a computer regularly, and of those, 99.8% have internet access [<xref ref-type="bibr" rid="ref20">20</xref>]. Despite the lack of access among some groups, current data demonstrate that an internet-based intervention has the potential to reach many participants who would benefit from increasing their PA.</p>
      <p>As we have previously detailed [<xref ref-type="bibr" rid="ref21">21</xref>], internet- or phone-based methods to connect with people with SCI are not yet in widespread use; however, the few reports in existence before this study demonstrated efficacy in providing health education [<xref ref-type="bibr" rid="ref22">22</xref>], developing self-management skills [<xref ref-type="bibr" rid="ref23">23</xref>], and reducing depressive symptoms along with pain [<xref ref-type="bibr" rid="ref24">24</xref>] among people with SCI. Although these studies offer evidence of efficacy that technology-mediated interventions can improve health, to our knowledge, none have focused on using regularly scheduled teleconferencing to overcome transportation barriers and increase PA while facilitating social support among peers. We identified one study from the literature that attempted to facilitate social support virtually through online message boards while investigating the effectiveness of using a web-based intervention to increase PA among adults with physical disability [<xref ref-type="bibr" rid="ref25">25</xref>]. However, the participants’ use of the boards was almost nonexistent, and the overall effectiveness of the intervention was inconclusive [<xref ref-type="bibr" rid="ref25">25</xref>]. Although the authors noted that the exact reason for low use of the message boards was unknown, some participants stated that they were uncomfortable sharing personal information with strangers on the web [<xref ref-type="bibr" rid="ref25">25</xref>].</p>
      <p>Our team created the Workout on Wheels internet intervention (WOW<italic>ii</italic>) program to meet the unique needs of people with SCI while delivering a theory-based health behavior intervention that facilitates videoconference meetings among groups of people with SCI interested in increasing PA [<xref ref-type="bibr" rid="ref26">26</xref>]. This intervention was adapted from the Workout on Wheels (WOW) program, a telephone-based program that yielded significant increases in time spent performing aerobic exercise [<xref ref-type="bibr" rid="ref27">27</xref>]. The WOW program was rooted in relapse prevention and social cognitive theories, both of which have been successfully implemented in interventions to increase PA [<xref ref-type="bibr" rid="ref28">28</xref>]. <xref rid="figure1" ref-type="fig">Figure 1</xref> depicts how each theory informs key components of the WOW<italic>ii</italic> interventions.</p>
      <p>Although the WOW successfully increased PA, the one-on-one meetings conducted by telephone were very time intensive per participant and did not allow the participants to connect with one another, which was a highly requested feature [<xref ref-type="bibr" rid="ref27">27</xref>]. The Workout on Wheels internet intervention (WOW<italic>ii</italic>) program translates the telephone-based WOW program into a web-based format delivered using web-based modules and virtual, group-based videoconference sessions. The advantages of WOW<italic>ii</italic> include leveraging technology to target groups of people with SCI to make resources available on demand while offering opportunities for participants to make personal connections throughout the intervention. This pilot study sought to characterize the feasibility of delivering the WOW<italic>ii</italic> program to 10 individuals with SCI based on the participants’ engagement in the program, defined as their attending weekly videoconference sessions, completing weekly online modules, and syncing their arm-based activity monitors weekly.</p>
      <fig id="figure1" position="float">
        <label>Figure 1</label>
        <caption>
          <p>Theoretical constructs and key components of the Workout on Wheels internet intervention (WOW<italic>ii</italic>) program.</p>
        </caption>
        <graphic xlink:href="rehab_v8i2e24276_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
      </fig>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <sec>
        <title>Recruitment</title>
        <p>This study was conducted at Baylor Scott &#38; White Institute for Rehabilitation in Dallas, Texas. Recruitment began in late 2016, and the study activities were concluded by May 2017. The Baylor Scott &#38; White Research Institute human subjects committee approved the study activities (Institutional Review Board #016-091), and all participants provided informed consent prior to beginning study participation. Eligible participants were between 18 and 70 years of age and were not pregnant; lived with an SCI at the level of C5 or below for more than 6 months; used a wheelchair; spoke and read English; had a computer and internet access; and could independently navigate the study website. Former patients with SCI from our inpatient rehabilitation hospital who agreed to be contacted for future studies were invited to participate in the study via telephone call or email, and staff handed out fliers at the outpatient clinic and the monthly support group for people with SCI. Study staff screened potential participants for eligibility by telephone. For those deemed eligible to enroll, study staff obtained a medical clearance by fax to participate in an intervention targeting physical activity from each participant’s primary care provider. Participants in this pilot study were not eligible to continue to participate in the full randomized controlled trial (RCT) study, which is currently under review.</p>
      </sec>
      <sec>
        <title>Intervention and Data Collection</title>
        <p>The WOW<italic>ii</italic> intervention comprises three key components: (1) the WOW<italic>ii</italic> exercise program provided via modules on the WOW<italic>ii</italic> website, (2) a starter package of exercise equipment, and (3) weekly virtual videoconference meetings led by the study staff to facilitate support for exercise. Study staff who led the videoconference meetings held master’s degrees in public health. They were trained to deliver the intervention and supervised by the principal investigator, an applied behavioral psychologist who has delivered exercise interventions to people with disabilities for over 20 years.</p>
        <p>For this pilot study, participants were given a username and password to access 4 weeks of the WOW<italic>ii</italic> website modules, which addressed getting started (eg, importance of exercise to health, benefits for people with disabilities, progression and safety, exercise basics), goal setting, identifying and addressing barriers to activity, and enlisting support (<xref rid="figure2" ref-type="fig">Figure 2</xref>). There was an activity at the end of each module that was designed to reinforce the material covered. Screenshots of the website and activities are available to view in <xref ref-type="supplementary-material" rid="app1">Multimedia Appendices 1</xref>-<xref ref-type="supplementary-material" rid="app4">4</xref>. The WOW<italic>ii</italic> website uses an application programming interface to collect data from each participant’s Polar account, allowing the study staff to download participant exercise data weekly in addition to their completed module activities.</p>
        <fig id="figure2" position="float">
          <label>Figure 2</label>
          <caption>
            <p>Workout on Wheels internet intervention (WOW<italic>ii</italic>) website and module topics covered during the pilot study.</p>
          </caption>
          <graphic xlink:href="rehab_v8i2e24276_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <p>The starter package of exercise equipment included resistance bands, an aerobic exercise DVD, and a pedal exerciser. Participants were also given Polar A300 wristwatch activity monitors [<xref ref-type="bibr" rid="ref29">29</xref>] and Polar H7 heart rate monitors [<xref ref-type="bibr" rid="ref29">29</xref>] (Polar Electro Oy) for recording the frequency and intensity of exercise bouts. These devices operate with proprietary Polar software, Polar Flow [<xref ref-type="bibr" rid="ref30">30</xref>], which tracks and displays its data on the watch that can be downloaded through a compatible smartphone app or a web browser directly from the Polar Flow website.</p>
        <p>Weekly videoconference meetings conducted over Skype were facilitated by a study coordinator and/or the principal investigator. The content of these discussions was designed to reinforce the information covered during each weekly module from the website. The format of each session provided time for the leader to briefly review the key points of the web-based module while facilitating conversation among the group regarding their experiences with each module topic. At the end of each session, leaders prompted the participants to complete the weekly module activity that reinforced the material discussed and asked participants to share their activity responses with the group. Session leaders recorded weekly attendance in a web-based spreadsheet.</p>
      </sec>
      <sec>
        <title>Analyses</title>
        <p>Summary statistics were generated to describe the levels of individual and overall participant engagement as measured by percentage of sessions attended, percentage of weeks of exercise tracking via the Polar device, and percentage of website module activities completed. The data were summarized using SAS, version 9.4 (SAS Institute).</p>
      </sec>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <p>A convenience sample of 10 people were enrolled in the pilot trial and provided engagement data for analysis. The sample was mostly male (6/10, 60%) and White (9/10, 90%) with an average age of 38.8 years (SD 16.6), and the participants had lived with their SCI for an average of 4.2 years (SD 2.6) (<xref ref-type="table" rid="table1">Table 1</xref>). A slight majority (6/10, 60%) were not currently employed, and most reported education levels of technical school/some college or a high school diploma (6/10, 60%). Of the 10 participants, 7 (70%) reported cervical-level injuries, with equal numbers of power and manual wheelchair users.</p>
      <table-wrap position="float" id="table1">
        <label>Table 1</label>
        <caption>
          <p>Participant demographics (N=10).</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="30"/>
          <col width="480"/>
          <col width="490"/>
          <thead>
            <tr valign="top">
              <td colspan="2">Variable</td>
              <td>Value</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td colspan="2">Age (years), mean (SD)</td>
              <td>38.8 (4.2)</td>
            </tr>
            <tr valign="top">
              <td colspan="2">Time with Injury (years), mean (SD)</td>
              <td>16.6 (2.6)</td>
            </tr>
            <tr valign="top">
              <td colspan="3">
                <bold>Sex, n (%)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Male</td>
              <td>6 (60)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Female</td>
              <td>4 (40)</td>
            </tr>
            <tr valign="top">
              <td colspan="3">
                <bold>Race, n (%)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>White</td>
              <td>9 (90)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Other</td>
              <td>1 (10)</td>
            </tr>
            <tr valign="top">
              <td colspan="3">
                <bold>Ethnicity, n (%)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Non-Hispanic</td>
              <td>10 (100)</td>
            </tr>
            <tr valign="top">
              <td colspan="3">
                <bold>Education level, n (%)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Bachelor's degree or higher</td>
              <td>4 (40)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>High school or below</td>
              <td>3 (30)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Technical school/some college</td>
              <td>3 (30)</td>
            </tr>
            <tr valign="top">
              <td colspan="3">
                <bold>Employment status, n (%)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Employed full- or part-time</td>
              <td>4 (40)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Not currently working</td>
              <td>6 (60)</td>
            </tr>
            <tr valign="top">
              <td colspan="3">
                <bold>Income level (US $), n (%)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>0-39,000</td>
              <td>6 (60)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>40,000-69,000</td>
              <td>1 (10)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>&#62;100,000</td>
              <td>3 (30)</td>
            </tr>
            <tr valign="top">
              <td colspan="3">
                <bold>Injury level, n (%)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Cervical</td>
              <td>7 (70)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Thoracic</td>
              <td>3 (30)</td>
            </tr>
            <tr valign="top">
              <td colspan="3">
                <bold>Wheelchair type, n (%)</bold>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Manual</td>
              <td>5 (50)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Power</td>
              <td>5 (50)</td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
      <p><xref ref-type="table" rid="table2">Tables 2</xref> and <xref ref-type="table" rid="table3">3</xref> demonstrate the level of overall engagement across the 10 participants. A total of 2 participants had low program engagement in the key components (2/12, 17%, and 5/12, 42%, respectively), with the other 8 demonstrating engagement rates of 75% to 100%. All participants attended at least 2 sessions; average videoconference session attendance ranged from 80% to 90% over the first 3 weeks and dropped to 70% in the fourth week. Most participants (9/10, 90%) completed the weekly web-based activities; however, only 70% (7/10) completed the final week’s activity. Of the total sample, 90% (9/10) synced their arm-based Polar activity monitors, with at least 60% (6/10) syncing the first 3 weeks; however, only 40% (4/10) synced the watch in the fourth week. The participants’ overall engagement as an average of each component across the 4 weeks was 75%. One participant only attended 2 virtual videoconference sessions and did not engage with the other components, and one participant completed 100% of the activities.</p>
      <table-wrap position="float" id="table2">
        <label>Table 2</label>
        <caption>
          <p>Participant engagement in key intervention components (N=12) over the 4-week pilot.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="150"/>
          <col width="230"/>
          <col width="100"/>
          <col width="110"/>
          <col width="110"/>
          <col width="100"/>
          <col width="200"/>
          <thead>
            <tr valign="top">
              <td>Participant #</td>
              <td>Activities</td>
              <td>Week 1</td>
              <td>Week 2</td>
              <td>Week 3</td>
              <td>Week 4</td>
              <td>Overall engagement, n (%)</td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td>201</td>
              <td>Attended session</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>11 (92)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Completed activity</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Tracked exercise</td>
              <td> </td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>202</td>
              <td>Attended session</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>11 (92)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Completed activity</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Tracked exercise</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td> </td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>203</td>
              <td>Attended session</td>
              <td>✓</td>
              <td> </td>
              <td>✓</td>
              <td> </td>
              <td>2 (17)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Completed activity</td>
              <td> </td>
              <td> </td>
              <td> </td>
              <td> </td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Tracked exercise</td>
              <td> </td>
              <td> </td>
              <td> </td>
              <td> </td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>204</td>
              <td>Attended session</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>12 (100)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Completed activity</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Tracked exercise</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>205</td>
              <td>Attended session</td>
              <td> </td>
              <td>✓</td>
              <td>✓</td>
              <td> </td>
              <td>5 (42)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Completed activity</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td> </td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Tracked exercise</td>
              <td> </td>
              <td> </td>
              <td> </td>
              <td> </td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>206</td>
              <td>Attended session</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>11 (92)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Completed activity</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Tracked exercise</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td> </td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>207</td>
              <td>Attended session</td>
              <td>✓</td>
              <td>✓</td>
              <td> </td>
              <td>✓</td>
              <td>10 (83)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Completed activity</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Tracked exercise</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td> </td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>208</td>
              <td>Attended session</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>10 (83)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Completed activity</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Tracked exercise</td>
              <td> </td>
              <td> </td>
              <td>✓</td>
              <td>✓</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>209</td>
              <td>Attended session</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td> </td>
              <td>9 (75)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Completed activity</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td> </td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Tracked exercise</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td> </td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>210</td>
              <td>Attended session</td>
              <td>✓</td>
              <td>✓</td>
              <td> </td>
              <td>✓</td>
              <td>9 (75)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Completed activity</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>✓</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Tracked exercise</td>
              <td>✓</td>
              <td>✓</td>
              <td> </td>
              <td> </td>
              <td>
                <break/>
              </td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
      <table-wrap position="float" id="table3">
        <label>Table 3</label>
        <caption>
          <p>Average engagement for the 3 components of the intervention.</p>
        </caption>
        <table width="1000" cellpadding="5" cellspacing="0" border="1" rules="groups" frame="hsides">
          <col width="420"/>
          <col width="110"/>
          <col width="110"/>
          <col width="110"/>
          <col width="110"/>
          <col width="140"/>
          <thead>
            <tr valign="top">
              <td>Component</td>
              <td colspan="6">Average engagement, n (%)</td>
            </tr>
            <tr valign="top">
              <td>
                <break/>
              </td>
              <td>Week 1</td>
              <td>Week 2</td>
              <td>Week 3</td>
              <td>Week 4</td>
              <td>Overall</td>
              <td>
                <break/>
              </td>
            </tr>
          </thead>
          <tbody>
            <tr valign="top">
              <td>All components (total=30)</td>
              <td>24 (80)</td>
              <td>25 (83.3)</td>
              <td>24 (80)</td>
              <td>17 (56.7)</td>
              <td>22.5 (75)</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>Session attendance </td>
              <td>9 (90)</td>
              <td>9 (90)</td>
              <td>8 (80)</td>
              <td>7 (70)</td>
              <td>33 (82.5)</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>Online activity completion</td>
              <td>9 (90)</td>
              <td>9 (90)</td>
              <td>9 (90)</td>
              <td>7 (70)</td>
              <td>34 (85)</td>
              <td>
                <break/>
              </td>
            </tr>
            <tr valign="top">
              <td>Exercising tracking rate </td>
              <td>6 (60)</td>
              <td>7 (70)</td>
              <td>6 (60)</td>
              <td>4 (40)</td>
              <td>23 (57.5)</td>
              <td>
                <break/>
              </td>
            </tr>
          </tbody>
        </table>
      </table-wrap>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>Although individual participation levels varied from week to week, the participants demonstrated consistent engagement during the 4-week pilot, with an overall engagement rate among the sample of 75% for attending the weekly videoconference meetings, completing the web-based activities, and wearing and syncing the arm-based Polar activity monitor. The participants showed the highest rates of engagement for completing the web-based module activities (85%) and attending the videoconference sessions (83%). These activities offer participants the space to learn about behavioral skills critical to successful behavior change and to discuss with the group their plans and personal experiences implementing those plans. The rate of syncing the Polar activity monitors was lower at 56%, although 90% of participants synced the watch in at least 1 week. It was unclear whether participants had trouble syncing their watches or were not exercising each week.</p>
        <p>This pilot study offers preliminary evidence that a web-based platform may be feasible for delivering a PA intervention program to meet the unique needs of people with SCI. Feedback from participants in this feasibility study was vital in implementing changes to the final website used during the RCT. For example, participants recommended incorporating a more robust peer mentoring component than we originally envisioned. The participants emphasized the importance of having individuals with SCI available to discuss their successes in increasing PA as a motivational piece for those starting the program. Additionally, participants advocated for adding cost-effective resources to the website, such as equipment and fitness programs, to best accommodate those whose disability may have limited access to disposable income. After conducting this initial feasibility study, the research team initiated testing the full 16-week theory- and evidence-based program in a randomized controlled trial with 168 total participants with SCI. That trial offered a more robust test of the effectiveness of the program in promoting increased moderate-intensity PA among a large SCI sample as well as the program’s effects on the participants’ self-reported self-efficacy and barriers to engaging in health promoting behaviors.</p>
        <p>In contrast with the study by Kosma et al [<xref ref-type="bibr" rid="ref25">25</xref>], which included a web-based message board that received only 6 postings over the course of the study, attendance at the virtual videoconference sessions was relatively high at 83%. During these weekly sessions, we observed that the participants were actively engaged in the conversation, and several reported that their favorite part of the program was connecting with other people with SCI. We believe that the high engagement we observed was due to participants being able to see one another and connect by videoconference, which mitigated any discomfort participants may have felt with sharing information on the web. Notably, a study published in 2019 that obtained qualitative feedback regarding a web-based portal aimed at increasing self-efficacy for exercise among a population with SCI reported that participants endorsed many of the features present in our program, such as self-regulation strategies, knowledge, and action planning [<xref ref-type="bibr" rid="ref31">31</xref>].</p>
        <p>Our observed attrition rate of 20% falls within an expected and acceptable range based on the previous WOW trial and research on weight loss and internet-based interventions. The WOW trial saw a 33% attrition rate [<xref ref-type="bibr" rid="ref27">27</xref>], while a 2011 systematic review examining dropout among participants of intensive lifestyle weight loss interventions (61 total studies) found that the reported attrition rates among participants ranged from 9% to 90% depending on the length and type of the intervention [<xref ref-type="bibr" rid="ref32">32</xref>]. Other systematic reviews examining participation in internet-based interventions for anxiety and depression found attrition rates of up to 83% [<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref34">34</xref>].</p>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>A potential study limitation was the lack of racial diversity among the participants despite good diversity in terms of education and income. Additionally, initial problems with Polar watch data exports limited our ability to accurately measure exercise in minutes. However, this pilot study yielded valuable knowledge that was implemented in the full RCT. For example, due to confusion regarding the difference between PA and exercise, more information was added to the first website module. Changes were also made to bolster the participants’ interaction by having peer mentors with SCI join virtual sessions, content was conveyed by adding more informational videos, and other content was added about important disability-related legislation.</p>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>The WOW<italic>ii</italic> program incorporated the following three novel components to increase PA among people with SCI: (1) group videoconferencing to leverage social support, (2) a web-based portal for information related to increasing PA, and (3) provision of exercise equipment to facilitate PA while mitigating barriers. Our pilot study showed promise regarding the ability of WOW<italic>ii</italic> to engage participants. The pilot study also led to improvements that were made before implementing the full RCT to study the effectiveness of the intervention. Given the prevalence of transportation issues and computer use among people with SCI, this intervention may be a valuable contribution to address the scarcity of lifestyle interventions which are accessible to this population.</p>
      </sec>
    </sec>
  </body>
  <back>
    <app-group>
      <supplementary-material id="app1">
        <label>Multimedia Appendix 1</label>
        <p>Screenshot of Module 1 (Getting Started) activity.</p>
        <media xlink:href="rehab_v8i2e24276_app1.png" xlink:title="PNG File , 107 KB"/>
      </supplementary-material>
      <supplementary-material id="app2">
        <label>Multimedia Appendix 2</label>
        <p>Screenshot of Module 2 (SMART Goals) activity.</p>
        <media xlink:href="rehab_v8i2e24276_app2.png" xlink:title="PNG File , 75 KB"/>
      </supplementary-material>
      <supplementary-material id="app3">
        <label>Multimedia Appendix 3</label>
        <p>Screenshot of Module 3 (Barriers) activity.</p>
        <media xlink:href="rehab_v8i2e24276_app3.png" xlink:title="PNG File , 31 KB"/>
      </supplementary-material>
      <supplementary-material id="app4">
        <label>Multimedia Appendix 4</label>
        <p>Screenshot of Module 4 (Enlisting Support) activity.</p>
        <media xlink:href="rehab_v8i2e24276_app4.png" xlink:title="PNG File , 40 KB"/>
      </supplementary-material>
    </app-group>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">PA</term>
          <def>
            <p>physical activity</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">RCT</term>
          <def>
            <p>randomized controlled trial</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">SCI</term>
          <def>
            <p>spinal cord injury</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">WOW</term>
          <def>
            <p>Workout on Wheels</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">WOW<italic>ii</italic></term>
          <def>
            <p>Workout on Wheels internet intervention</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <ack>
      <p>This work was funded by the National Institute for Disability, Independent Living, and Rehabilitation Research (NIDILRR, 90IF0091-01-00). NIDILRR is a center within the Administration for Community Living (ACL), Department of Health and Human Services (HHS). The content of this paper does not necessarily represent the policy of NIDILRR, ACL, and HHS, and it is not endorsed by the US Federal Government. Skype is a trademark or other intellectual property of the Microsoft group of companies, and this publication is not affiliated, sponsored, authorized, or otherwise associated with or by the Microsoft group of companies.</p>
    </ack>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
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