<?xml version="1.0" encoding="utf-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v2.0 20040830//EN" "http://dtd.nlm.nih.gov/publishing/2.0/journalpublishing.dtd">
<article xmlns:xlink="http://www.w3.org/1999/xlink" article-type="research-article" dtd-version="2.0">
  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">JRAT</journal-id>
      <journal-id journal-id-type="nlm-ta">JMIR Rehabil Assist Technol</journal-id>
      <journal-title>JMIR Rehabilitation and Assistive Technologies</journal-title>
      <issn pub-type="epub">2369-2529</issn>
      <publisher>
        <publisher-name>JMIR Publications</publisher-name>
        <publisher-loc>Toronto, Canada</publisher-loc>
      </publisher>
    </journal-meta>
    <article-meta>
    <article-id pub-id-type="publisher-id">v4i1e1</article-id>
    <article-id pub-id-type="pmid">28582262</article-id>
    <article-id pub-id-type="doi">10.2196/rehab.6376</article-id>
    <article-categories>
      <subj-group subj-group-type="heading">
        <subject>Original Paper</subject>
      </subj-group>
      <subj-group subj-group-type="article-type">
        <subject>Original Paper</subject>
      </subj-group>
    </article-categories>
    <title-group>
      <article-title>Technologies to Support Community-Dwelling Persons With Dementia: A Position Paper on Issues Regarding Development, Usability, Effectiveness and Cost-Effectiveness, Deployment, and Ethics</article-title>
    </title-group>
    <contrib-group>
      <contrib contrib-type="editor">
        <name>
          <surname>Eysenbach</surname>
          <given-names>Gunther</given-names>
        </name>
      </contrib>
    </contrib-group>
    <contrib-group>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Davies</surname>
          <given-names>Richard</given-names>
        </name>
      </contrib>
      <contrib contrib-type="reviewer">
        <name>
          <surname>Pino</surname>
          <given-names>Maribel</given-names>
        </name>
      </contrib>
    </contrib-group>
    <contrib-group>
      <contrib contrib-type="author" id="contrib1" corresp="yes">
      <name name-style="western">
        <surname>Meiland</surname>
        <given-names>Franka</given-names>
      </name>
      <degrees>PhD</degrees>
      <xref rid="aff01" ref-type="aff">1</xref>
      <address>
        <institution>Department of Psychiatry</institution>
        <institution>VU University medical centre</institution>
        <addr-line>AJ Ernststraat 1187</addr-line>
        <addr-line>Amsterdam, 1081 HL</addr-line>
        <country>Netherlands</country>
        <phone>31 207885623</phone>
        <fax>31 207885623</fax>
        <email>fj.meiland@vumc.nl</email>
      </address>  
      <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-6219-5390</ext-link></contrib>
      <contrib contrib-type="author" id="contrib2">
        <name name-style="western">
          <surname>Innes</surname>
          <given-names>Anthea</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff02" ref-type="aff">2</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-5591-4083</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib3">
        <name name-style="western">
          <surname>Mountain</surname>
          <given-names>Gail</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff03" ref-type="aff">3</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-5417-7691</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib4">
        <name name-style="western">
          <surname>Robinson</surname>
          <given-names>Louise</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff04" ref-type="aff">4</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0003-0209-2503</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib5">
        <name name-style="western">
          <surname>van der Roest</surname>
          <given-names>Henriëtte</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff05" ref-type="aff">5</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-9898-923X</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib6">
        <name name-style="western">
          <surname>García-Casal</surname>
          <given-names>J Antonio</given-names>
        </name>
        <degrees>DClinPsy</degrees>
        <xref rid="aff06" ref-type="aff">6</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0003-0533-4918</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib7">
        <name name-style="western">
          <surname>Gove</surname>
          <given-names>Dianne</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff07" ref-type="aff">7</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-4281-3494</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib8">
        <name name-style="western">
          <surname>Thyrian</surname>
          <given-names>Jochen René</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff08" ref-type="aff">8</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-6889-693X</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib9">
        <name name-style="western">
          <surname>Evans</surname>
          <given-names>Shirley</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff09" ref-type="aff">9</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-6158-1433</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib10">
        <name name-style="western">
          <surname>Dröes</surname>
          <given-names>Rose-Marie</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff01" ref-type="aff">1</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-4812-1229</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib11">
        <name name-style="western">
          <surname>Kelly</surname>
          <given-names>Fiona</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff10" ref-type="aff">10</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-5608-0332</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib12">
        <name name-style="western">
          <surname>Kurz</surname>
          <given-names>Alexander</given-names>
        </name>
        <degrees>MD, PhD</degrees>
        <xref rid="aff11" ref-type="aff">11</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-5042-7614</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib13">
        <name name-style="western">
          <surname>Casey</surname>
          <given-names>Dympna</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff12" ref-type="aff">12</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-5341-597X</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib14">
        <name name-style="western">
          <surname>Szcześniak</surname>
          <given-names>Dorota</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff13" ref-type="aff">13</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-8899-8842</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib15">
        <name name-style="western">
          <surname>Dening</surname>
          <given-names>Tom</given-names>
        </name>
        <degrees>MD, FRCPsych</degrees>
        <xref rid="aff14" ref-type="aff">14</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0003-3387-4241</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib16">
        <name name-style="western">
          <surname>Craven</surname>
          <given-names>Michael P</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff15" ref-type="aff">15</xref>
        <xref rid="aff16" ref-type="aff">16</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0001-5682-6360</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib17">
        <name name-style="western">
          <surname>Span</surname>
          <given-names>Marijke</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff17" ref-type="aff">17</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-7977-8776</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib18">
        <name name-style="western">
          <surname>Felzmann</surname>
          <given-names>Heike</given-names>
        </name>
        <degrees>PhD</degrees>
        <xref rid="aff18" ref-type="aff">18</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-7355-6451</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib19">
        <name name-style="western">
          <surname>Tsolaki</surname>
          <given-names>Magda</given-names>
        </name>
        <degrees>MD, PhD</degrees>
        <xref rid="aff19" ref-type="aff">19</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-2072-8010</ext-link>
      </contrib>
      <contrib contrib-type="author" id="contrib20">
        <name name-style="western">
          <surname>Franco-Martin</surname>
          <given-names>Manuel</given-names>
        </name>
        <degrees>MD, PhD</degrees>
        <xref rid="aff20" ref-type="aff">20</xref>
        <ext-link ext-link-type="orcid">http://orcid.org/0000-0002-3639-2523</ext-link>
      </contrib>
    </contrib-group>
    <aff id="aff01">
    <sup>1</sup>
    <institution>Department of Psychiatry</institution>
    <institution>VU University medical centre</institution>  
    <addr-line>Amsterdam</addr-line>
    <country>Netherlands</country></aff>
    <aff id="aff02">
      <sup>2</sup>
      <institution>Universities of Salford and Stirling UK</institution>
      <addr-line>Manchester, Stirling</addr-line>
      <country>United Kingdom</country>
    </aff>
    <aff id="aff03">
    <sup>3</sup>
    <institution>School of Health and Related Research (ScHARR)</institution>
    <institution>University of Sheffield</institution>  
    <addr-line>Sheffield</addr-line>
    <country>United Kingdom</country></aff>
    <aff id="aff04">
    <sup>4</sup>
    <institution>Institute for Ageing</institution>
    <institution>Newcastle University</institution>  
    <addr-line>Newcastle</addr-line>
    <country>United Kingdom</country></aff>
    <aff id="aff05">
    <sup>5</sup>
    <institution>Department of General Practice and Elderly Care Medicine</institution>
    <institution>VU university medical centre</institution>  
    <addr-line>Amsterdam</addr-line>
    <country>Netherlands</country></aff>
    <aff id="aff06">
    <sup>6</sup>
    <institution>Iberian Research Psychosciences Institute</institution>
    <institution>Psychosocial Rehabilitation Centre, Intras Foundation</institution>  
    <addr-line>Zamora</addr-line>
    <country>Spain</country></aff>
    <aff id="aff07">
      <sup>7</sup>
      <institution>Alzheimer Europe</institution>
      <addr-line>Luxembourg</addr-line>
      <country>Luxembourg</country>
    </aff>
    <aff id="aff08">
      <sup>8</sup>
      <institution>German Center for Neurodegenerative Diseases (DZNE), Site Rostock</institution>
      <addr-line>Greifswald</addr-line>
      <country>Germany</country>
    </aff>
    <aff id="aff09">
    <sup>9</sup>
    <institution>Association for Dementia Studies</institution>
    <institution>University of Worcester</institution>  
    <addr-line>Worcester</addr-line>
    <country>United Kingdom</country></aff>
    <aff id="aff10">
    <sup>10</sup>
    <institution>Centre for Person-centred Practice Research</institution>
    <institution>Queen Margaret University</institution>  
    <addr-line>Edinburgh</addr-line>
    <country>United Kingdom</country></aff>
    <aff id="aff11">
      <sup>11</sup>
      <institution>Technische Universität München</institution>
      <addr-line>Munchen</addr-line>
      <country>Germany</country>
    </aff>
    <aff id="aff12">
    <sup>12</sup>
    <institution>School of Nursing and Midwifery</institution>
    <institution>National University of Ireland Galway</institution>  
    <addr-line>Galway</addr-line>
    <country>Ireland</country></aff>
    <aff id="aff13">
    <sup>13</sup>
    <institution>Department of Psychiatry</institution>
    <institution>Wroclaw Medical University</institution>  
    <addr-line>Wroclaw</addr-line>
    <country>Poland</country></aff>
    <aff id="aff14">
    <sup>14</sup>
    <institution>Division of Psychiatry &#38; Applied Psychology</institution>
    <institution>University of Nottingham</institution>  
    <addr-line>Nottingham</addr-line>
    <country>United Kingdom</country></aff>
    <aff id="aff15">
    <sup>15</sup>
    <institution>NIHR MindTech Healthcare Technology Co-operative</institution>
    <institution>Institute of Mental Health</institution>  
    <institution>University of Nottingham Innovation Park</institution>  
    <addr-line>Nottingham</addr-line>
    <country>United Kingdom</country></aff>
    <aff id="aff16">
    <sup>16</sup>
    <institution>Bioengineering Research Group</institution>
    <institution>Faculty of Engineering</institution>  
    <institution>University of Nottingham</institution>  
    <addr-line>Nottingham</addr-line>
    <country>United Kingdom</country></aff>
    <aff id="aff17">
      <sup>17</sup>
      <institution>Windesheim University of Applied Sciences</institution>
      <addr-line>Zwolle</addr-line>
      <country>Netherlands</country>
    </aff>
    <aff id="aff18">
      <sup>18</sup>
      <institution>National University of Ireland Galway</institution>
      <addr-line>Galway</addr-line>
      <country>Ireland</country>
    </aff>
    <aff id="aff19">
    <sup>19</sup>
    <institution>Memory and dementia outpatient clinic</institution>
    <institution>3rd Department of Neurology</institution>  
    <institution>Aristotle University of Thessaloniki</institution>  
    <addr-line>Thessaloniki</addr-line>
    <country>Greece</country></aff>
    <aff id="aff20">
    <sup>20</sup>
    <institution>Iberian Research Psychosciences Institute</institution>
    <institution>Psychiatric Department in Zamora Hospital</institution>  
    <institution>Salamanca University</institution>  
    <addr-line>Zamora</addr-line>
    <country>Spain</country></aff>
    <author-notes>
      <corresp>Corresponding Author: Franka Meiland 
      <email>fj.meiland@vumc.nl</email></corresp>
    </author-notes>
    <pub-date pub-type="collection"><season>Jan-Jun</season><year>2017</year></pub-date>
    <pub-date pub-type="epub">
      <day>16</day>
      <month>01</month>
      <year>2017</year>
    </pub-date>
    <volume>4</volume>
    <issue>1</issue>
    <elocation-id>e1</elocation-id>
    <!--history from ojs - api-xml-->
    <history>
      <date date-type="received">
        <day>20</day>
        <month>7</month>
        <year>2016</year>
      </date>
      <date date-type="rev-request">
        <day>25</day>
        <month>8</month>
        <year>2016</year>
      </date>
      <date date-type="rev-recd">
        <day>16</day>
        <month>10</month>
        <year>2016</year>
      </date>
      <date date-type="accepted">
        <day>24</day>
        <month>10</month>
        <year>2016</year>
      </date>
    </history>
    <!--(c) the authors - correct author names and publication date here if necessary. Date in form ', dd.mm.yyyy' after jmir.org-->
    <copyright-statement>©Franka Meiland, Anthea Innes, Gail Mountain, Louise Robinson, Henriëtte van der Roest, J Antonio García-Casal, Dianne Gove, Jochen René Thyrian, Shirley Evans, Rose-Marie Dröes, Fiona Kelly, Alexander Kurz, Dympna Casey, Dorota Szcześniak, Tom Dening, Michael P Craven, Marijke Span, Heike Felzmann, Magda Tsolaki, Manuel Franco-Martin. Originally published in JMIR Rehabilitation and Assistive Technology (http://rehab.jmir.org), 16.01.2017.</copyright-statement>
    <copyright-year>2017</copyright-year>
    <license license-type="open-access" xlink:href="http://creativecommons.org/licenses/by/2.0/">
      <p>This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Rehabilitation and Assistive Technology, is properly cited. The complete bibliographic information, a link to the original publication on http://rehab.jmir.org/, as well as this copyright and license information must be included.</p>
    </license>  
    <self-uri xlink:href="http://rehab.jmir.org/2017/1/e1/" xlink:type="simple"/>
    <abstract>
      <sec sec-type="background">
        <title>Background</title>
        <p>With the expected increase in the numbers of persons with dementia, providing timely, adequate, and affordable care and support is challenging. Assistive and health technologies may be a valuable contribution in dementia care, but new challenges may emerge.</p>
      </sec>
      <sec sec-type="objective">
        <title>Objective</title>
        <p>The aim of our study was to review the state of the art of technologies for persons with dementia regarding issues on development, usability, effectiveness and cost-effectiveness, deployment, and ethics in 3 fields of application of technologies: (1) support with managing everyday life, (2) support with participating in pleasurable and meaningful activities, and (3) support with dementia health and social care provision. The study also aimed to identify gaps in the evidence and challenges for future research.</p>
      </sec>
      <sec sec-type="methods">
        <title>Methods</title>
        <p>Reviews of literature and expert opinions were used in our study. Literature searches were conducted on usability, effectiveness and cost-effectiveness, and ethics using PubMed, Embase, CINAHL, and PsycINFO databases with no time limit. Selection criteria in our selected technology fields were reviews in English for community-dwelling persons with dementia. Regarding deployment issues, searches were done in Health Technology Assessment databases.</p>
      </sec>
      <sec sec-type="results">
        <title>Results</title>
        <p>According to our results, persons with dementia want to be included in the development of technologies; there is little research on the usability of assistive technologies; various benefits are reported but are mainly based on low-quality studies; barriers to deployment of technologies in dementia care were identified, and ethical issues were raised by researchers but often not studied. Many challenges remain such as including the target group more often in development, performing more high-quality studies on usability and effectiveness and cost-effectiveness, creating and having access to high-quality datasets on existing technologies to enable adequate deployment of technologies in dementia care, and ensuring that ethical issues are considered an important topic for researchers to include in their evaluation of assistive technologies.</p>
      </sec>
      <sec sec-type="conclusions">
        <title>Conclusions</title>
        <p>Based on these findings, various actions are recommended for development, usability, effectiveness and cost-effectiveness, deployment, and ethics of assistive and health technologies across Europe. These include avoiding replication of technology development that is unhelpful or ineffective and focusing on how technologies succeed in addressing individual needs of persons with dementia. Furthermore, it is suggested to include these recommendations in national and international calls for funding and assistive technology research programs. Finally, practitioners, policy makers, care insurers, and care providers should work together with technology enterprises and researchers to prepare strategies for the implementation of assistive technologies in different care settings. This may help future generations of persons with dementia to utilize available and affordable technologies and, ultimately, to benefit from them.</p>
      </sec>
    </abstract>
    <kwd-group>
      <kwd>dementia</kwd>
      <kwd>technology</kwd>
      <kwd>evaluation studies</kwd>
      <kwd>diffusion of innovation</kwd>
      <kwd>ethics</kwd>
    </kwd-group></article-meta>
  </front>
  <body>
    <sec sec-type="introduction">
      <title>Introduction</title>
      <p>Due to our aging societies, dementia has become a 21st-century global public health concern, placing considerable burden on not only the individual and their family but also current and future service provision [<xref ref-type="bibr" rid="ref1">1</xref>]. Worldwide prevalence is around 46 million, a figure predicted to treble to 131.5 million by 2050, with current care costs recently estimated at US $818 billion [<xref ref-type="bibr" rid="ref2">2</xref>]. Among all chronic diseases, dementia is one of the most important contributors to dependence, disability, and care home placement [<xref ref-type="bibr" rid="ref3">3</xref>]. Despite a global policy push toward more timely diagnosis and earlier intervention, considerable geographical inequalities in the provision of post-diagnostic care and support services exist [<xref ref-type="bibr" rid="ref4">4</xref>]. One aspect of postdiagnostic support, which may enable persons with dementia to remain independent for a longer time and thus potentially leading to cost savings by delaying entry into care and nursing homes [<xref ref-type="bibr" rid="ref2">2</xref>,<xref ref-type="bibr" rid="ref3">3</xref>], is assistive technology. Assistive technology for persons with dementia can be defined as “Any item, piece of equipment, product or system driven by electronics, whether acquired commercially, off-the-shelf, modified or customized, that is used to help persons with dementia in dealing with the consequences of dementia” (see also Marshall [<xref ref-type="bibr" rid="ref5">5</xref>]; Assistive Technology Industry Association [<xref ref-type="bibr" rid="ref6">6</xref>]; ISO9999 [<xref ref-type="bibr" rid="ref7">7</xref>]). The technology does not necessarily need to be “purposely designed” [<xref ref-type="bibr" rid="ref8">8</xref>] for persons with dementia, as many mainstream technologies can be adapted to their changing needs. Important need areas in dementia are memory support, information, company, reducing psychological distress, and engaging in daytime activities [<xref ref-type="bibr" rid="ref9">9</xref>,<xref ref-type="bibr" rid="ref10">10</xref>]. Various technologies have been developed to address these needs, such as electronic calendars, Web-based information systems, video-calling, and electronic activity support systems [<xref ref-type="bibr" rid="ref11">11</xref>-<xref ref-type="bibr" rid="ref13">13</xref>].</p>
      <p>Evaluation studies have found that persons with dementia are positive about using electronic devices to facilitate their independence and reduce family stress [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref14">14</xref>]. Furthermore, small-scale studies have found that assistive technologies improve independence [<xref ref-type="bibr" rid="ref15">15</xref>], behavioral symptoms in persons with dementia [<xref ref-type="bibr" rid="ref16">16</xref>], and quality of life [<xref ref-type="bibr" rid="ref15">15</xref>], and stress in carers [<xref ref-type="bibr" rid="ref16">16</xref>].</p>
      <p>Despite the promising benefits of technological support systems, several issues remain before they will really make a difference in the field of dementia care. For example, the predominant use of technological solutions for safety and security and carer reassurance rather than for lifestyle in general [<xref ref-type="bibr" rid="ref17">17</xref>]; the slow uptake and implementation of assistive technologies; the lack of high-quality scientific research into the effectiveness and cost-effectiveness of assistive technologies in dementia care [<xref ref-type="bibr" rid="ref18">18</xref>,<xref ref-type="bibr" rid="ref19">19</xref>], the lack of successful commercialization of prototype technologies; and the limited attention to aesthetics, which can make many technological support systems feel stigmatizing [<xref ref-type="bibr" rid="ref20">20</xref>]. Furthermore, professionals and society also seem to lack an applied understanding of the potential of assistive technology in dementia because it is not being integrated into mainstream dementia care practice [<xref ref-type="bibr" rid="ref20">20</xref>,<xref ref-type="bibr" rid="ref21">21</xref>].</p>
      <p>The need to address these issues has been widely acknowledged. For example, joint research efforts on assistive technologies in dementia were identified via a taskforce on Assistive Technology setup within INTERDEM (an interdisciplinary European research network of more than 160 members, collaborating to develop and carry out pan-European research on early, timely, and quality psychosocial interventions in dementia [<xref ref-type="bibr" rid="ref22">22</xref>]). Experts from this taskforce worked together to discuss and reach consensus regarding the current state of affairs regarding (assistive) technologies for community-dwelling people with dementia. This resulted in this position paper.</p>
      <p>Based on literature and expert opinions, key areas were considered including development issues, usability, effectiveness and cost-effectiveness, deployment, and ethics of (assistive) technologies for community-dwelling people with dementia. The term “assistive technology” included a wide range of aids, appliances, and whole-system applications; consequently, discussions were focused on technologies that addressed the following 3 areas of global need:</p>
      <p>1. Devices intended to help persons living with dementia to manage their everyday life across the disease journey, such as electronic calendars and reminders for activities, medication reminders, aids to perform activities of daily life, robots, and navigation systems.</p>
      <p>2. Technologies to help people engage in meaningful and pleasurable activities such as cognitive stimulation and physical activities, as well as technologies to improve social participation, contact, and support.</p>
      <p>3. Health care technologies that aim to support professional organizations and systems within dementia health and social care, such as behavior monitoring, shared decision making, and Global Positioning System (GPS) tracking systems.</p>
      <p>We concluded with a set of recommendations for key stakeholders including the research community, technology developers (industry and business), care commissioners, and care providers to better prepare them to ensure the ongoing delivery of high-quality, efficient care and support to the growing numbers of persons living with dementia and their families.</p>
    </sec>
    <sec sec-type="methods">
      <title>Methods</title>
      <p>Literature reviews were performed by members of the taskforce Assistive Technology, who met twice (Ljubljana, September 2015; Berlin, October 2015) to discuss the aim and methodology of this study and divide the work. Each subsequent section was led by 2 taskforce members and prepared by a subgroup of the taskforce Assistive Technology.</p>
      <p>The section on technology development was based on expert opinion and relevant literature, among other previous reviews of taskforce members [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref24">24</xref>]. For the sections on usability, effectiveness and cost-effectiveness, and ethical issues, separate literature searches were conducted in PubMed, CINAHL, PsycINFO, and Embase databases. Common search terms were used for dementia (“Dementia”[Mesh]) OR (dement* OR alzheimer* OR lewy OR CJD OR JCD OR creutzfeldt OR binswanger OR korsakoff OR frontotemporal OR FTD OR “vascular dementia” OR VaD OR “pick disease” OR “picks disease”) and technology ((assistiv* OR orthotic* OR supportiv* OR electronic*) AND (technolog* OR device*)) OR telecare OR “Self-Help Devices”[Mesh] OR (“information communication technology” OR ICT), added with specific terms for the sections on usability ((usability AND (computer OR technology OR software OR virtual reality)) and ethics (ethic*). Inclusion criteria were reviews in English, reporting (partly) on persons with dementia living in the community, and technologies in 1 or more of the 3 selected areas (daily living, meaningful and pleasurable activities, and health care technology). There was no restriction on publication dates, and the searches were finalized in January 2016.</p>
      <p>All records from the searches were reviewed by at least two independent researchers in each section to check whether they should be included. Another researcher was involved to reach consensus in cases of disagreement. Reviews that met the inclusion criteria were included, and the results of the reviews (or single studies in the reviews if relevant) were summarized. For the section on deployment, searches were conducted in specific Health Technology Assessment databases, using the search terms: assistive technology dementia.</p>
    </sec>
    <sec sec-type="results">
      <title>Results</title>
      <sec>
        <title>Development Issues Regarding Assistive Technologies for Daily Living, Meaningful and Pleasurable Activities, and Health Care Technology</title>
        <p>In the past, devices for older people were generally created by technologists with little attention to the specific needs of older end users, and thus the users’ requirements of devices. Nowadays, there is wider understanding of the importance of engaging end users at all stages of technology development to ensure their needs are addressed and to promote acceptance of technological aids. However, challenges in the development of technological devices were identified as follows: How can technologies address the heterogeneous needs of persons with dementia? Should technologies be designed specifically for dementia or adapted from mainstream technology? What methods are more efficacious when developing technologies for persons living with dementia? Finally, we addressed what challenges are to be faced regarding developmental issues in the 3 selected application areas of assistive technology.</p>
        <sec>
          <title>Technologies to Address the Heterogeneous Needs of Persons With Dementia</title>
          <p>To develop technologies that are useful and valuable for persons with dementia, it is important to know what kind of assistance is needed. This requires a thorough understanding of the different types of dementia and associated impairments, individual experiences and coping mechanisms, and the continuous changing situation during the dementia “journey.” It is also important to be attentive to needs such as a sense of self-esteem and feeling respected, which are related to higher levels of well-being and quality of life, as highlighted in Maslow’s “hierarchy of needs” [<xref ref-type="bibr" rid="ref25">25</xref>,<xref ref-type="bibr" rid="ref17">17</xref>]. People with dementia can express their needs [<xref ref-type="bibr" rid="ref26">26</xref>] and preferences [<xref ref-type="bibr" rid="ref27">27</xref>] consistently, even in an advanced stage of dementia [<xref ref-type="bibr" rid="ref28">28</xref>]. Therefore, to really understand what it is to live with dementia and which needs should be addressed, people with dementia should be asked about their needs and experiences and be involved early in the process of development of supportive tools and interventions. Till now, very few technologies have actually been designed to meet the specific needs of people living with dementia [<xref ref-type="bibr" rid="ref29">29</xref>], and only few of these prototypes have been adopted for commercial development.</p>
        </sec>
        <sec>
          <title>Technologies Designed Purposively for Dementia or Adapted From Mainstream Technology</title>
          <p>Technologies can be divided into those designed specifically for persons with dementia as opposed to technologies that have been developed in the mainstream and lend themselves well to support people with cognitive difficulties. For example, the functionality of some forms of telecare technology, such as GPS, webcams, and apps (Joint Improvement Team, 2016), is being superseded by readily accessible off-the-shelf devices that can successfully assist people to navigate their day. Also, recent work has confirmed that persons with dementia can be supported to use touchscreen computing for leisure and recreation in line with the rest of society [<xref ref-type="bibr" rid="ref29">29</xref>]. Nevertheless, the complex sensory, perceptual, and cognitive changes caused by dementia can make using mainstream devices problematic for some persons with dementia, and therefore for the foreseeable future, some demand for bespoke devices will continue.</p>
        </sec>
        <sec>
          <title>Methods of Technology Development in Dementia</title>
          <p>In developing assistive technologies in health care, there has been a shift from expert- and technology-led design toward a user-driven approach, and it is more common to now involve end users.</p>
          <p>Examples of methods that support end user involvement and aim for sustainable eHealth innovations are the holistic approaches of the roadmap of the Centre for eHealth Research and Disease Management (CeHRes) [<xref ref-type="bibr" rid="ref30">30</xref>] and Contextual Design [<xref ref-type="bibr" rid="ref31">31</xref>]. Both methods are rooted in human-centered design (HCD) and emphasize 3 interrelated components: technology, people, and organization (health care environment). The CeHRes roadmap focuses, in particular, on the health domain and combines HCD principles with business modeling.</p>
          <p>For dementia, the drive to ensure engagement at all stages of technology development is underpinned by the principles of person-centered care and, in a broader perspective, by a social inclusive society. This includes the coproduction of new innovations for research and for practice, with the involvement of end users from the outset [<xref ref-type="bibr" rid="ref32">32</xref>,<xref ref-type="bibr" rid="ref33">33</xref>]. In practice, however, people with dementia have rarely been involved in technology development, with user acceptability tending to be assessed via family carers and others [<xref ref-type="bibr" rid="ref11">11</xref>,<xref ref-type="bibr" rid="ref24">24</xref>,<xref ref-type="bibr" rid="ref34">34</xref>]. Successful examples of collaborative working with people with mild-to-moderate dementia are emerging [<xref ref-type="bibr" rid="ref14">14</xref>,<xref ref-type="bibr" rid="ref33">33</xref>,<xref ref-type="bibr" rid="ref35">35</xref>-<xref ref-type="bibr" rid="ref37">37</xref>]. However, people with more severe dementia are less often included in development of assistive technologies.</p>
        </sec>
        <sec>
          <title>Challenges in the Development of Assistive Technology</title>
          <p>Challenges in the development of assistive technology include the need for personalized and tailored technologies in dementia. A “one size fits all” is not an optimal solution because of the individual variations in needs and abilities. The development of sustainable assistive technology for persons with more severe dementia is a challenge, as is how to develop technologies in a way that will help to make the world a more “dementia-friendly” place [<xref ref-type="bibr" rid="ref38">38</xref>]. Examples of assistive technologies that can help persons with dementia in their daily life are simple aids such as calendars and reminders but also more complicated devices such as robots that perform a social role or augment individual human capabilities through cognitive prosthetics [<xref ref-type="bibr" rid="ref39">39</xref>]. There are companies who anticipate providing inclusive assistive technology solutions for older people, including those with dementia, for example, Alcove [<xref ref-type="bibr" rid="ref40">40</xref>]. One research challenge is how to develop assistive technologies that address the emotional state of persons with dementia during everyday tasks [<xref ref-type="bibr" rid="ref41">41</xref>]. One of the challenges in the field of health care technology, which supports organizational and supportive systems of dementia care, is to integrate technology into the built environment, such as lighting, floor coverings, and improved way-finding (eg, via improved signage), taking into account the varying and changing needs of the residents [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>]. Another challenge is to integrate technology into the routine health care, using information and communication technology (ICT) in the clinical assessment of cognitive, behavioral, and physical functioning of persons with dementia [<xref ref-type="bibr" rid="ref44">44</xref>].</p>
        </sec>
        <sec>
          <title>Conclusion on State of Affairs Development of (Assistive) Technologies in Dementia</title>
          <p>Research has revealed that persons with dementia are enthusiastic about using assistive technology to remain independent and also about taking part in technology design [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref33">33</xref>]. At the same time, some challenges remain, such as how to personalize and tailor technologies to the individual and changing needs and abilities of persons with dementia. We envisage that the involvement of end users in developing new assistive technologies will continue to grow, and that more applications of existing technology using mobile phones or apps will be put to use to benefit persons with dementia.</p>
        </sec>
      </sec>
      <sec>
        <title>Usability of Assistive and Health Technology in Dementia</title>
        <p>The International Organization for Standardization defines usability as “the extent to which a product can be used by specified users to achieve specified goals with effectiveness, efficiency and satisfaction in a specified context of use” [<xref ref-type="bibr" rid="ref45">45</xref>]. Thus, usability refers to the capability of the technology to be understood, learned, and used under specified conditions. The literature review on usability issues in dementia resulted in 89 papers (<xref ref-type="fig" rid="figure1">Figure 1</xref>). The main results are discussed in the following sections.</p>
        <fig id="figure1" position="float">
          <label>Figure 1</label>
          <caption>
            <p>Flowchart of systematic review on usability.</p>
          </caption>
          <graphic xlink:href="rehab_v4i1e1_fig1.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <sec>
          <title>Usability of Technologies to Support Persons With Dementia in Everyday Life</title>
          <p>Little research so far has been conducted in the field of assistive technologies in community dementia care and support, with only 3 studies exploring usability in supporting everyday life with a Day Navigator [<xref ref-type="bibr" rid="ref46">46</xref>], a GPS [<xref ref-type="bibr" rid="ref47">47</xref>] and a timer device [<xref ref-type="bibr" rid="ref48">48</xref>]. In the study by Meiland et al, 42 participants and carers considered the Day Navigator to be mainly user-friendly, but conclusions about usefulness were limited due to insufficient duration of the testing period [<xref ref-type="bibr" rid="ref46">46</xref>]. The GPS system was tested among 33 dyads, with only 1 leaving the study because of technical reasons. Participants with dementia who went outside unaccompanied took the GPS with them 67% of the time. Also, 80% (20/25) of the caregivers said that the use of the technology was not difficult, and almost all of them felt that they were in control of the secured website where they could track and trace their relatives (92%; 23/25). The study does not provide specific information about usability outcomes apart from ease and frequency of use and the fact that the participants with dementia did not seem to mind that they heard a voice from their GPS without notification [<xref ref-type="bibr" rid="ref47">47</xref>]. The timer device was used for a stove and tested with 9 older adults with cognitive impairment or dementia and 5 relatives. The authors found that end users scarcely participated in the process of choosing and adapting the device. Although the device provided increased safety, there were also some unforeseen problems, such as not fully understanding how the device worked. The authors stressed the importance of actively involving users in home modifications with assistive technologies and providing medium- and longer-term follow-up of the technological support [<xref ref-type="bibr" rid="ref48">48</xref>].</p>
        </sec>
        <sec>
          <title>Usability of Technologies to Support Participation in Meaningful and Pleasurable Activities</title>
          <p>In research on technology to participate in meaningful and pleasurable activities, for example, cognitive interventions for persons with dementia, usability issues are often not mentioned. Jelcic et al [<xref ref-type="bibr" rid="ref49">49</xref>] reported a positive perception of technology-based cognitive therapy, as participants would recommend it to others and were satisfied with the utility and appeal of this intervention. Zaccarelli et al [<xref ref-type="bibr" rid="ref50">50</xref>] found that the educational level of users was important, as results of the studies on people with Alzheimer’s disease, mild cognitive impairment and healthy adults showed that participants with a higher education level found it easier to learn how to use the ICT platform. Lee et al [<xref ref-type="bibr" rid="ref51">51</xref>] reported that the usability of their computer-based cognitive intervention was good. Persons with dementia were highly motivated in using it, and their sense of achievement was enhanced; they took pride in showing others that they could operate the computer [<xref ref-type="bibr" rid="ref51">51</xref>]. Gillespie et al [<xref ref-type="bibr" rid="ref52">52</xref>] suggested that large-scale studies of assistive technology to improve cognition should also focus on functional areas, for example, prompting, navigating, and reminding, rather than on the specific content of the devices itself.</p>
        </sec>
        <sec>
          <title>Factors Influencing Usability</title>
          <p>Over time, persons with dementia may have reduced ability for new learning, which may impact actual use of technology because learning and technology use are inseparable and proceed together [<xref ref-type="bibr" rid="ref53">53</xref>]. Understanding how persons with dementia access and embrace technology is vital in order to develop usable and acceptable technological solutions. Technology use by older adults has been criticized for not eliciting and including their interests [<xref ref-type="bibr" rid="ref54">54</xref>]. Devices should be adjusted to each individual, achieving better tailored interventions, and assistive technologies should be embedded in a person-centred model [<xref ref-type="bibr" rid="ref55">55</xref>]. A good example of this is the provision of feedback sessions to ensure that the person with dementia and carer understand the assistive technologies, to answer questions, and to collaboratively discuss recommendations for improvement [<xref ref-type="bibr" rid="ref56">56</xref>]. A recent review (not limited to dementia) on mHealth applications suggested the adoption of automated evaluation mechanisms to improve the empirical methods to assess usability [<xref ref-type="bibr" rid="ref57">57</xref>].</p>
          <p>Furthermore, a good match between the person and the technology is required because if this is not achieved well from the end user’s perspective, the technology may be ignored or not be used optimally [<xref ref-type="bibr" rid="ref58">58</xref>]. Bardram et al [<xref ref-type="bibr" rid="ref59">59</xref>] emphasized the importance of deploying assistive technologies in a real-world setting, outside the laboratory, and also the need to perform longitudinal studies that assess the evolution of the relationship between the end user and the technology [<xref ref-type="bibr" rid="ref59">59</xref>]. A person’s acceptance of assistive technologies can vary during the course of dementia. For example, acceptance can improve when symptoms start to threaten the independence of the person [<xref ref-type="bibr" rid="ref60">60</xref>]. The ability to use assistive technology may also vary. Over time, a decreasing use of technology is seen in people with cognitive impairment [<xref ref-type="bibr" rid="ref61">61</xref>].</p>
          <p>It has been suggested that usability studies of assistive technologies should be designed in several stages: predeployment (observation sessions, focus groups with people with dementia, carers, and professionals); deployment (carrying out long-term observations and quantitative and qualitative assessments in real settings); and postdeployment (feedback sessions) in close partnership with end users, carers, and specialists [<xref ref-type="bibr" rid="ref62">62</xref>].</p>
        </sec>
        <sec>
          <title>Usability in the Area of Computer Technologies</title>
          <p>In the area of computer technologies, usability of interfaces has received special attention. Research on the preferences of persons with dementia has indicated that touchscreen devices are preferred over mouse or keyboard input devices [<xref ref-type="bibr" rid="ref63">63</xref>]. Direct response devices using a touchscreen reduce the distance between the subject (seeing the stimuli) and the causal effect (providing the answer), which enhances the person´s involvement in the task. The previous experience of people with dementia with computers affects which type of interface device they prefer, with experienced users preferring the mouse. However, although the mouse is the most demanding device in terms of cognitive and motor demands, there can also be problems with touchscreens in terms of accuracy that may be frustrating for the end user [<xref ref-type="bibr" rid="ref64">64</xref>]. Computer literacy has an important role in usability: lack of computer experience was reported to decrease the odds of successful use of technology [<xref ref-type="bibr" rid="ref65">65</xref>]. Thus, pretest, treatment, or intervention training sessions could be used to enable persons with mild cognitive impairments and early dementia to become familiar with novel technologies [<xref ref-type="bibr" rid="ref66">66</xref>-<xref ref-type="bibr" rid="ref69">69</xref>]. The need for including performance tests to enhance the ecological validity of assistive technologies has been highlighted, such as measuring the user’s motivation [<xref ref-type="bibr" rid="ref54">54</xref>]. Although there is a prejudice that assistive technologies are not “elderly friendly,” in fact the evidence points in the opposite direction: when older adults get the opportunity to use computers, they regard them as a “status symbol” often associated with youth; as a consequence, the use of computers could have a positive effect on self-confidence and self-esteem [<xref ref-type="bibr" rid="ref70">70</xref>].</p>
          <p>Regarding the assessment of the usability of assistive technologies and user satisfaction, various tools were used, for example, the usefulness, satisfaction and ease of use questionnaire [<xref ref-type="bibr" rid="ref71">71</xref>]; the Everyday Technology Use Questionnaire [<xref ref-type="bibr" rid="ref72">72</xref>]; the Quebec User Evaluation of Satisfaction with Assistive Technology [<xref ref-type="bibr" rid="ref51">51</xref>]; and the model of technology acceptance, specifically developed to test the acceptance of assistive social agents by older adults [<xref ref-type="bibr" rid="ref73">73</xref>]. There is a lack of tools to evaluate the usability of assistive technologies in persons with severe dementia.</p>
          <p>To conclude, despite advances in the field of technology-based interventions for persons living with dementia, few applications have been analyzed for their usability. Technologies can be used by many persons with dementia, but additional support is often needed from informal caregivers or professionals. To promote better utilization of technologies in dementia care, a better understanding is needed of their usability for persons with dementia, people’s preferences for specific interfaces, and their acceptance of different technologies.</p>
        </sec>
      </sec>
      <sec>
        <title>Effectiveness and Cost-Effectiveness of Assistive and Health Care Technologies in Dementia</title>
        <p>The flowchart in <xref ref-type="fig" rid="figure2">Figure 2</xref> illustrates the literature retrieved on effectiveness and cost-effectiveness of assistive and health care technologies. Eighteen reviews met our inclusion criteria, most of which (n=10) described a combination of the 3 technology domains we focused on in this study. One review focused on technologies to support persons with dementia in everyday life, 3 on technologies for engagement in pleasant and meaningful activities, and 4 on health care technology to support organizational and supportive systems. From the selected reviews, 55 individual studies described the effects of technologies on persons with dementia, the results of which are described in the following sections. None of the empirical studies described the cost-effectiveness of assistive and health care technologies for community-dwelling persons with dementia.</p>
        <fig id="figure2" position="float">
          <label>Figure 2</label>
          <caption>
            <p>Flowchart of systematic review on effectiveness and cost-effectiveness.</p>
          </caption>
          <graphic xlink:href="rehab_v4i1e1_fig2.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <sec>
          <title>Assistive Technologies to Support Persons With Dementia in Everyday Life</title>
          <p>Within this domain, many devices have been tested for their effectiveness. For example, a calendar was positively evaluated by more than half of the 21 participants [<xref ref-type="bibr" rid="ref74">74</xref>]; a training device (based on errorless learning) to guide people with dementia in using a mobile phone was reportedly effective [<xref ref-type="bibr" rid="ref75">75</xref>]; prompting devices to support in activities of daily life or in memory were found useful [<xref ref-type="bibr" rid="ref76">76</xref>,<xref ref-type="bibr" rid="ref77">77</xref>] and effective [<xref ref-type="bibr" rid="ref76">76</xref>-<xref ref-type="bibr" rid="ref80">80</xref>]; and prompts were found effective for traveling [<xref ref-type="bibr" rid="ref81">81</xref>-<xref ref-type="bibr" rid="ref84">84</xref>]. However, another prompting device found no impact on quality of life [<xref ref-type="bibr" rid="ref85">85</xref>], which might have resulted from the many technological problems encountered during the effect pilot study. The NeuroPage [<xref ref-type="bibr" rid="ref86">86</xref>] was tested in a randomized controlled trial (RCT) and showed a significant reduction in memory and planning failures by providing prompts; however, this study included patients with brain injury, and only a small number had dementia. Although tracking devices are said to be effective [<xref ref-type="bibr" rid="ref87">87</xref>,<xref ref-type="bibr" rid="ref88">88</xref>], 1 study showed that only a minority used such devices successfully, and 1 patient was injured by a passing vehicle [<xref ref-type="bibr" rid="ref89">89</xref>]. Two studies also identified positive effects of tracking devices for caregivers (relief or reduction of emotional distress) [<xref ref-type="bibr" rid="ref87">87</xref>,<xref ref-type="bibr" rid="ref90">90</xref>].</p>
        </sec>
        <sec>
          <title>Assistive Technologies to Support People With Dementia in Meaningful and Pleasurable Activities</title>
          <p>Within the domain of technologies for meaningful or pleasurable activities, computer programs with cognitive training applications showed improvements in task performance or cognition in persons with Alzheimer’s dementia [<xref ref-type="bibr" rid="ref70">70</xref>,<xref ref-type="bibr" rid="ref91">91</xref>], recall [<xref ref-type="bibr" rid="ref92">92</xref>], global cognitive functioning, and emotion [<xref ref-type="bibr" rid="ref93">93</xref>,<xref ref-type="bibr" rid="ref94">94</xref>]. However, devices with prompts for creative activities were found to be not effective [<xref ref-type="bibr" rid="ref95">95</xref>,<xref ref-type="bibr" rid="ref96">96</xref>], although participants liked the activities with an ePAD (Engaging Platform for Art Development) [<xref ref-type="bibr" rid="ref95">95</xref>]. Social robot therapy for stimulating interaction showed an improvement in brain activity in half of the 14 participants [<xref ref-type="bibr" rid="ref97">97</xref>]. Research into the use of multimedia tools to support people with dementia has reported improvements in well-being [<xref ref-type="bibr" rid="ref98">98</xref>,<xref ref-type="bibr" rid="ref99">99</xref>], mood [<xref ref-type="bibr" rid="ref100">100</xref>], psychological stability [<xref ref-type="bibr" rid="ref101">101</xref>], and social interaction and engagement [<xref ref-type="bibr" rid="ref100">100</xref>,<xref ref-type="bibr" rid="ref102">102</xref>-<xref ref-type="bibr" rid="ref107">107</xref>]. In another study, a music tool was enjoyed by its users, but the prompts proved difficult to understand for the person with dementia [<xref ref-type="bibr" rid="ref96">96</xref>]. Telephones or videophones have been reported as being easy to use for persons with dementia and helpful for maintaining social contacts, and they positively affected self-esteem [<xref ref-type="bibr" rid="ref108">108</xref>-<xref ref-type="bibr" rid="ref110">110</xref>].</p>
        </sec>
        <sec>
          <title>Health Care Technologies</title>
          <p>Health care technologies to facilitate health care delivery for people with dementia included sensors to monitor behavior, virtual reality, and video conferences. Sensors and smart home technologies are said to provide a good image of performed activities [<xref ref-type="bibr" rid="ref111">111</xref>] and were reportedly successful in preventing major incidents [<xref ref-type="bibr" rid="ref48">48</xref>,<xref ref-type="bibr" rid="ref112">112</xref>,<xref ref-type="bibr" rid="ref113">113</xref>]. Reported effectiveness of these tools in helping persons with dementia to live longer in the community varied [<xref ref-type="bibr" rid="ref114">114</xref>,<xref ref-type="bibr" rid="ref115">115</xref>]. One large controlled study [<xref ref-type="bibr" rid="ref15">15</xref>] concluded that smart home technologies helped persons with dementia by improving confidence, ability to maintain community living for a longer time, and reducing need for care visits. A single case study found a reduction in required support, perceived anxiety, and confusion by the person with dementia [<xref ref-type="bibr" rid="ref116">116</xref>]. Comparison of the use of video conferences for, for example, clinical assessment showed no differences compared with face-to-face assessments [<xref ref-type="bibr" rid="ref117">117</xref>-<xref ref-type="bibr" rid="ref119">119</xref>]. Clinical improvements were found for almost half of the study sample that received telecare, which consisted of telemedicine, tele-education, and telecounseling services [<xref ref-type="bibr" rid="ref120">120</xref>], and this kind of telecare could be promising for rural populations [<xref ref-type="bibr" rid="ref119">119</xref>].</p>
        </sec>
        <sec>
          <title>Conclusion of Effectiveness and Cost-Effectiveness Assistive and Health Technology in Dementia</title>
          <p>To summarize, various benefits of assistive technologies for persons with dementia have been reported. However, the results described need to be interpreted with caution because the majority of the included studies were uncontrolled studies with relatively small sample sizes. Reviews on cost-effectiveness studies of assistive and health care technologies in dementia were not found.</p>
        </sec>
      </sec>
      <sec>
        <title>Deployment of Assistive and Health Technology</title>
        <p>Results regarding deployment were based on (1) recommendations for deployment of health technology identified by an expert panel and (2) a literature search using databases regarding health technology assessments (HTAs) and health services or technology assessments (HSTAs). These databases were chosen because they are specifically designed to give evidence-based recommendations and are directed at a nonscientific audience, for example, stakeholders who want to deploy health technology. The search resulted in 17 papers, of which 5 were relevant for the issues under consideration.</p>
        <sec>
          <title>Deployment Issues</title>
          <p>According to the Ambient Assisted Living Association (AALA) [<xref ref-type="bibr" rid="ref121">121</xref>], “the market is growing beyond its traditional boundaries and this is attracting a growing interest by potential investors, the ICT industry and all service and care providers.” The landscape of the market will be deeply modified by a combination of a demand pull (by the rapidly growing population of older persons) and a technology push (through development of new ICT solutions and services) ([<xref ref-type="bibr" rid="ref121">121</xref>], p. 76). A key recommendation of the AALA was to develop a European observatory with the mission to become the main source of trusted and high-quality information and data on the market to inform all stakeholders.</p>
          <p>The next 3 paragraphs consider factors that influence deployment related to demand pull of stakeholders in general, health care professionals, and persons living with dementia.</p>
        </sec>
        <sec>
          <title>Deployment Factors: Stakeholders in General</title>
          <p>Stakeholders need trusted and high-quality information from HTAs or HSTAs. However, reviewing the current situation of HTA or HSTA delivers disappointing results in that these data, mainly provided by national bodies, are often incomplete, with many variations in definitions, information provided, and quality and reliability of the data [<xref ref-type="bibr" rid="ref121">121</xref>].</p>
          <p>The users of these data include health care providers, health service researchers, policy makers, funders, consumers, and information professionals (eg, in United States [<xref ref-type="bibr" rid="ref122">122</xref>]; United Kingdom [<xref ref-type="bibr" rid="ref123">123</xref>]; Germany [<xref ref-type="bibr" rid="ref124">124</xref>]). Solely searching the HTA databases that provide English literature with the search term “assistive technology dementia” reveals few results (ie, United States: 14 books; United Kingdom: 3 items). Two of them provide facilitators and barriers (expanded upon later) to the deployment of technology: Jimison et al [<xref ref-type="bibr" rid="ref125">125</xref>] and Finkelstein et al [<xref ref-type="bibr" rid="ref126">126</xref>]. One is a systematic review on the effectiveness of assistive technology which does identify some of the barriers that are also mentioned in Jimison et al [<xref ref-type="bibr" rid="ref125">125</xref>] and Finkelstein et al [<xref ref-type="bibr" rid="ref126">126</xref>], and the other is a bibliographic record of an ongoing health technology assessment being undertaken [<xref ref-type="bibr" rid="ref127">127</xref>]. One result was a Cochrane protocol focusing on the efficacy of assistive technology for memory support in dementia [<xref ref-type="bibr" rid="ref128">128</xref>]. The other results were either not related to dementia or were not focusing on assistive technology.</p>
        </sec>
        <sec>
          <title>Deployment Factors: Health Care Professionals</title>
          <p>A range of constraints limiting deployment and related to the technology and health care sectors were identified at a workshop (2014) involving Ambient Assistive Living (AAL) and Joint Programme for Neurodegenerative Diseases (JPND) stakeholders; 25% of the projects funded by AAL and JPND are about developing ICT-based solutions for support and care of older adults with cognitive impairments [<xref ref-type="bibr" rid="ref129">129</xref>]. These constraints came from a range of sectors including health and social care and business, covering aspects such as open standards, finance and business models, skills, and simply knowing what is available and where there are gaps in the market.</p>
          <p>When assistive technology is used to enable support and care processes, barriers include the following: lack of usability; problems with access to the health IT application, low computer literacy in patients and clinicians, insufficient basic formal training in health IT applications; physicians’ concerns about more work; workflow issues; problems related to new system deployment, including concerns about confidentiality of patient information; depersonalization; incompatibility with current health care practices; lack of standardization; and problems with reimbursement [<xref ref-type="bibr" rid="ref121">121</xref>]. Facilitators for the utilization of health IT included ease of use, perceived usefulness, efficiency of use, availability of support, comfort in use, and site location [<xref ref-type="bibr" rid="ref126">126</xref>].</p>
        </sec>
        <sec>
          <title>Deployment Factors: Persons Living With Dementia</title>
          <p>Barriers for deployment of assistive technologies for the end user, which might also apply to a wider audience than dementia, include the following: usability problems, unreliable technology, the lack of consumers’ perceived benefit from using the system, inconvenience, data entry being cumbersome, and the intervention not fitting into the user’s daily routine. Deployment appeared to be more successful if the intervention could be delivered by technology that consumers already use daily for other purposes, and that satisfactorily meet their needs [<xref ref-type="bibr" rid="ref125">125</xref>].</p>
          <p>In conclusion, to promote successful deployment of assistive and health technologies in dementia care, it is essential that the technologies are reliable, user friendly, and useful; and that there is a single centrally funded access point to high-quality information regarding assistive technology products relating to dementia for all stakeholders. The Assistive Technology Dementia website [<xref ref-type="bibr" rid="ref130">130</xref>] provides such a platform but is reliant on short-term funding (donations and grants), which means that optimization of information and sustainability are compromised. Furthermore, education and training in the field of technologies in dementia care should be available for all stakeholders.</p>
        </sec>
      </sec>
      <sec>
        <title>Ethical Considerations</title>
        <p>The analyses of the literature search regarding ethical considerations resulted in 33 references in which ethical issues were discussed linked to the use of assistive technology by or for persons with dementia living at home (see flowchart in <xref ref-type="fig" rid="figure3">Figure 3</xref>). The documents reviewed all covered at least one of the 3 assistive technology domains in the following numbers: technologies to support people in managing everyday life (13), to support in pleasurable and meaningful activities (1), health care technologies (1), and a combination of domains 1 and 2 (5), domains 1 and 3 (1), and all 3 domains (12). There was variation in the terminology used to cover ethical issues in relationship to assistive technology and in the coverage and the depth of consideration of such issues. <xref ref-type="table" rid="table1">Table 1</xref> shows 7 categories of ethical issues resulting from the analysis and the reference numbers of the articles or studies in which they were addressed.</p>
        <fig id="figure3" position="float">
          <label>Figure 3</label>
          <caption>
            <p>Flow chart of systematic review on ethics.</p>
          </caption>
          <graphic xlink:href="rehab_v4i1e1_fig3.png" alt-version="no" mimetype="image" position="float" xlink:type="simple"/>
        </fig>
        <table-wrap position="float" id="table1">
          <label>Table 1</label>
          <caption>
            <p>Ethical issues addressed in the articles reviewed.</p>
          </caption>
          <table width="602" cellpadding="7" cellspacing="0" border="1" rules="groups" frame="hsides">
            <col width="115"/>
            <col width="156"/>
            <col width="287"/>
            <thead>
              <tr valign="top">
                <td>Category of ethical issue</td>
                <td>Additional topics included</td>
                <td>Articles or studies that addressed these ethical issues</td>
              </tr>
            </thead>
            <tbody>
              <tr valign="top">
                <td>Autonomy, freedom // paternalism, disempowerment</td>
                <td>Informed consent, independence, the right to take risks, individuality, self-esteem and identity versus the use of restraint and coercive measures, over-protection</td>
                <td>Cash [<xref ref-type="bibr" rid="ref131">131</xref>]; Kang et al [<xref ref-type="bibr" rid="ref132">132</xref>]; Landau et al [<xref ref-type="bibr" rid="ref133">133</xref>]; Landau et al [<xref ref-type="bibr" rid="ref134">134</xref>]; Landau et al [<xref ref-type="bibr" rid="ref135">135</xref>]; Landau and Werner [<xref ref-type="bibr" rid="ref136">136</xref>]; Lindqvist et al [<xref ref-type="bibr" rid="ref137">137</xref>]; Mahoney et al [<xref ref-type="bibr" rid="ref138">138</xref>]; Mao et al [<xref ref-type="bibr" rid="ref139">139</xref>]; Martin and Cunningham [<xref ref-type="bibr" rid="ref140">140</xref>]; McCabe and Innes [<xref ref-type="bibr" rid="ref141">141</xref>]; McKinstry and Sheikh [<xref ref-type="bibr" rid="ref142">142</xref>]; Mehrabian et al [<xref ref-type="bibr" rid="ref143">143</xref>]; Miskelly [<xref ref-type="bibr" rid="ref88">88</xref>]; Olsson et al [<xref ref-type="bibr" rid="ref144">144</xref>]; Pino et al [<xref ref-type="bibr" rid="ref145">145</xref>]; Plastow [<xref ref-type="bibr" rid="ref146">146</xref>]; Pot et al [<xref ref-type="bibr" rid="ref47">47</xref>]; Rauhala and Topo [<xref ref-type="bibr" rid="ref12">12</xref>]; Robinson et al [<xref ref-type="bibr" rid="ref14">14</xref>]; Robinson et al [<xref ref-type="bibr" rid="ref147">147</xref>]; Robinson et al [<xref ref-type="bibr" rid="ref148">148</xref>]; Siotia and Simpson [<xref ref-type="bibr" rid="ref149">149</xref>]; Sorell and Draper [<xref ref-type="bibr" rid="ref150">150</xref>]; Van Berlo [<xref ref-type="bibr" rid="ref151">151</xref>]; Welsh et al [<xref ref-type="bibr" rid="ref152">152</xref>]; Werner and Landau [<xref ref-type="bibr" rid="ref134">134</xref>]; White and Montgomery [<xref ref-type="bibr" rid="ref153">153</xref>]; Zwijsen et al [<xref ref-type="bibr" rid="ref154">154</xref>]</td>
              </tr>
              <tr valign="top">
                <td>Dignity, personhood // stigma, discrimination</td>
                <td>Devaluation</td>
                <td>Hughes et al [<xref ref-type="bibr" rid="ref155">155</xref>]; Kang et al [<xref ref-type="bibr" rid="ref132">132</xref>]; Landau et al [<xref ref-type="bibr" rid="ref135">135</xref>]; Landau and Werner [<xref ref-type="bibr" rid="ref136">136</xref>]; Mahoney et al [<xref ref-type="bibr" rid="ref138">138</xref>]; Mao et al [<xref ref-type="bibr" rid="ref139">139</xref>]; Marshall [<xref ref-type="bibr" rid="ref156">156</xref>]; McCabe and Innes [<xref ref-type="bibr" rid="ref141">141</xref>]; Plastow [<xref ref-type="bibr" rid="ref146">146</xref>]; Robinson et al [<xref ref-type="bibr" rid="ref14">14</xref>]; Robinson et al [<xref ref-type="bibr" rid="ref147">147</xref>]; Robinson et al [<xref ref-type="bibr" rid="ref148">148</xref>]; Sorell and Draper [<xref ref-type="bibr" rid="ref150">150</xref>]; Werner and Landau [<xref ref-type="bibr" rid="ref157">157</xref>]; White and Montgomery [<xref ref-type="bibr" rid="ref153">153</xref>]; Zwijsen et al [<xref ref-type="bibr" rid="ref154">154</xref>]</td>
              </tr>
              <tr valign="top">
                <td>Social inclusion // replacement or loss of human contact</td>
                <td>Simulated presence, staffing issues, and deception</td>
                <td>Cash [<xref ref-type="bibr" rid="ref131">131</xref>]; Kang et al [<xref ref-type="bibr" rid="ref132">132</xref>]; Landau [<xref ref-type="bibr" rid="ref133">133</xref>]; Landau et al [<xref ref-type="bibr" rid="ref135">135</xref>]; Mahoney et al [<xref ref-type="bibr" rid="ref138">138</xref>]; Marshall [<xref ref-type="bibr" rid="ref156">156</xref>]; Martin and Cunningham [<xref ref-type="bibr" rid="ref140">140</xref>]; Pino et al [<xref ref-type="bibr" rid="ref145">145</xref>]; Plastow [<xref ref-type="bibr" rid="ref146">146</xref>]; Robinson et al [<xref ref-type="bibr" rid="ref147">147</xref>]; Siotia and Simpson [<xref ref-type="bibr" rid="ref149">149</xref>]; Van Berlo [<xref ref-type="bibr" rid="ref151">151</xref>]; Welsh et al [<xref ref-type="bibr" rid="ref152">152</xref>]; Werner and Landau [<xref ref-type="bibr" rid="ref157">157</xref>]; Zwijsen et al [<xref ref-type="bibr" rid="ref154">154</xref>]</td>
              </tr>
              <tr valign="top">
                <td>Privacy and data security</td>
                <td>Confidentiality</td>
                <td>Frisardi and Imbimbo [<xref ref-type="bibr" rid="ref158">158</xref>]; Kearns and Fozard [<xref ref-type="bibr" rid="ref159">159</xref>]; Landau et al [<xref ref-type="bibr" rid="ref133">133</xref>]; Landau et al [<xref ref-type="bibr" rid="ref134">134</xref>]; Landau et al [<xref ref-type="bibr" rid="ref135">135</xref>]; Landau and Werner [<xref ref-type="bibr" rid="ref136">136</xref>]; Mahoney et al [<xref ref-type="bibr" rid="ref138">138</xref>]; McCabe and Innes [<xref ref-type="bibr" rid="ref141">141</xref>]; McKinstry and Sheikh [<xref ref-type="bibr" rid="ref142">142</xref>]; Mehrabian et al [<xref ref-type="bibr" rid="ref143">143</xref>]; Rauhala and Topo [<xref ref-type="bibr" rid="ref12">12</xref>]; Sorell and Draper [<xref ref-type="bibr" rid="ref150">150</xref>]; White and Montgomery [<xref ref-type="bibr" rid="ref153">153</xref>]; Zwijsen et al [<xref ref-type="bibr" rid="ref154">154</xref>]</td>
              </tr>
              <tr valign="top">
                <td>Overreliance on technology, new risks, false security</td>
                <td><break/></td>
                <td>Landau et al [<xref ref-type="bibr" rid="ref135">135</xref>]; Mao et al [<xref ref-type="bibr" rid="ref139">139</xref>]; Marshall [<xref ref-type="bibr" rid="ref156">156</xref>]; Martin and Cunningham [<xref ref-type="bibr" rid="ref140">140</xref>]</td>
              </tr>
              <tr valign="top">
                <td>Beneficence // nonmaleficence</td>
                <td>Wellbeing, minimizing distress and harm (not only for people with dementia), for whose benefit the AT is used</td>
                <td>Cash [<xref ref-type="bibr" rid="ref131">131</xref>]; Hughes et al [<xref ref-type="bibr" rid="ref155">155</xref>]) Kang et al [<xref ref-type="bibr" rid="ref132">132</xref>]; Landau et al [<xref ref-type="bibr" rid="ref133">133</xref>]; Landau et al [<xref ref-type="bibr" rid="ref135">135</xref>]; Landau and Werner [<xref ref-type="bibr" rid="ref136">136</xref>]; Lindqvist et al [<xref ref-type="bibr" rid="ref137">137</xref>]; Mahoney et al [<xref ref-type="bibr" rid="ref138">138</xref>]; Marshall [<xref ref-type="bibr" rid="ref156">156</xref>]; McCabe and Innes [<xref ref-type="bibr" rid="ref141">141</xref>]; Mehrabian et al [<xref ref-type="bibr" rid="ref143">143</xref>]; Pino et al [<xref ref-type="bibr" rid="ref145">145</xref>]; Pot et al [<xref ref-type="bibr" rid="ref47">47</xref>]; Robinson et al [<xref ref-type="bibr" rid="ref147">147</xref>]; Robinson et al [<xref ref-type="bibr" rid="ref148">148</xref>]; Siotia and Simpson [<xref ref-type="bibr" rid="ref149">149</xref>]; Sorell and Draper [<xref ref-type="bibr" rid="ref150">150</xref>]</td>
              </tr>
              <tr valign="top">
                <td>Equity or justice</td>
                <td>Issues related to the individual and society (including costs)</td>
                <td>Cash [<xref ref-type="bibr" rid="ref131">131</xref>]; Mahoney et al [<xref ref-type="bibr" rid="ref138">138</xref>]; Martin and Cunningham [<xref ref-type="bibr" rid="ref140">140</xref>]; Mehrabian et al [<xref ref-type="bibr" rid="ref143">143</xref>]; Rauhala and Topo [<xref ref-type="bibr" rid="ref12">12</xref>]; Siotia and Simpson [<xref ref-type="bibr" rid="ref149">149</xref>]; Van Berlo [<xref ref-type="bibr" rid="ref151">151</xref>]; Welsh et al [<xref ref-type="bibr" rid="ref152">152</xref>]; Werner and Landau [<xref ref-type="bibr" rid="ref157">157</xref>]; Zwijsen et al [<xref ref-type="bibr" rid="ref154">154</xref>]</td>
              </tr>
            </tbody>
          </table>
        </table-wrap>
        <p>A wide range of ethical issues were addressed but with a focus primarily on 3 of the 4 biomedical ethical principles (respect for autonomy, beneficence, and nonmaleficence) as well as on issues associated with care ethics and human rights (eg, social inclusion, human contact, personhood, dignity, and discrimination). Most researchers addressed a comprehensive range of ethical issues in the introduction to their article (ie, to contextualize their study or argument), but some gave much less attention to them when reporting their findings.</p>
        <p>Several researchers (eg, Hughes et al [<xref ref-type="bibr" rid="ref155">155</xref>]; Landau et al [<xref ref-type="bibr" rid="ref133">133</xref>,<xref ref-type="bibr" rid="ref135">135</xref>]; and Pino et al [<xref ref-type="bibr" rid="ref145">145</xref>]) demonstrated a nuanced understanding of various ethical issues associated with the use of assistive technologies specifically for or by persons with dementia. This involved, for example, reflection on opposing concepts and concerns, such as social inclusion versus loss of human contact, or respect for autonomy versus concerns about safety (touching on coercion and paternalism). Some authors (McCabe and Innes [<xref ref-type="bibr" rid="ref141">141</xref>]; Robinson et al [<xref ref-type="bibr" rid="ref14">14</xref>]) emphasized that ethical issues are related to the way assistive technologies are used rather than inherent in particular devices or systems (eg, a device is not inherently stigmatizing; tracking devices may, depending on the situation and the individual, be experienced as either promoting or reducing freedom and autonomy).</p>
        <p>Issues were frequently described in terms of ethical dilemmas of which 2 are notable. The first is about privacy and respect for autonomy versus safety and minimizing risks. The more safety a person with dementia wishes to have, the more it may be necessary for them (or others on their behalf) to accept some loss of privacy or autonomy and with various possible negative consequences (eg, safety at the expense of reduced quality of life, some risk but possibility to delay entry into residential care, deterioration of carer’s quality of life or health). The second ethical dilemma is about obtaining informed consent from persons with dementia due to possible difficulties understanding complex technology and loss of awareness over time of the presence or purpose of assistive technology, or that data is being collected on them.</p>
      </sec>
    </sec>
    <sec sec-type="discussion">
      <title>Discussion</title>
      <sec>
        <title>Principal Findings</title>
        <p>The aim of our study was to describe the state of the art regarding development issues, usability, effectiveness and cost-effectiveness, deployment, and ethics of (assistive) technologies for community-dwelling persons with dementia, and based on that, to recommend a roadmap for development, research, and practice to support and promote the use of assistive technology, thus preparing society for the growing number of people with dementia.</p>
        <p>A literature review was performed in the fields of usability, effectiveness and cost-effectiveness, and ethics. Most reviews were found in the field of usability, with the majority of these papers evaluating technologies to support daily living. In the field of effectiveness and cost-effectiveness, most reviews described a combination of the 3 technology domains we focused on in this study, and in the field of ethics, topics were addressed that were less related to the domain of technology, but rather to the way technology was used and the consequences for the user regarding, for example, autonomy and dignity.</p>
        <p>Based on the results of the literature reviews and expert opinions, the following can be concluded about the state of the art of assistive technology for persons with dementia:</p>
        <p>Development issues: Research has revealed that people with dementia are enthusiastic about using assistive technology to remain independent and also about taking part in technology design [<xref ref-type="bibr" rid="ref23">23</xref>,<xref ref-type="bibr" rid="ref33">33</xref>]. It is envisaged that the involvement of end users in the development of new assistive technologies will continue to grow, and that more applications of existing technology, using, for example, mobile phones and apps, will be put to use to benefit persons with dementia. We also anticipate that more companies will show an interest in this market, thus promoting the daily use of assistive technologies in dementia care. However there are also challenges such as how to personalize and tailor technologies to the individual needs and abilities of the person with dementia, how to address the emotional state of persons with dementia during everyday tasks [<xref ref-type="bibr" rid="ref41">41</xref>], and how to integrate technology into the built environment and routine health care.</p>
        <p>Usability issues: Little research so far has been conducted in community dementia care and support, with only a few studies exploring the usability of assistive technology in supporting everyday life [<xref ref-type="bibr" rid="ref37">37</xref>,<xref ref-type="bibr" rid="ref47">47</xref>,<xref ref-type="bibr" rid="ref48">48</xref>]. The results showed that people with dementia were able to use the technology, but that additional support by informal caregivers or professionals was often needed. Furthermore, research showed that successful use of technology was related to computer literacy [<xref ref-type="bibr" rid="ref65">65</xref>], and level of education of the users [<xref ref-type="bibr" rid="ref50">50</xref>]. In the field of meaningful and pleasurable technology-based interventions, such as cognitive interventions for people with dementia, usability is generally not mentioned. However, a recent review showed promising findings for these activities using touchscreen technologies [<xref ref-type="bibr" rid="ref160">160</xref>]. More research on usability in all areas of assistive technology is needed.</p>
        <p>Effectiveness and cost-effectiveness: Various benefits of assistive technologies for people with dementia have been reported, such as cognitive and social functioning, mood and well-being, and reduction in service use. However, these findings need to be interpreted with caution because the majority of the included studies were uncontrolled, with half of them having included less than 10 persons with dementia. Most of the controlled studies included between 10 and 30 participants, and there were only 2 RCTs (1 with 46 and 1 with 143 participants of which less than 8% were people with dementia). No studies were found on the cost-effectiveness of assistive technologies or health technology interventions.</p>
        <p>Deployment: Many barriers were identified ranging from a lack of knowledge about technology solutions, lack of usability and training, low computer literacy to incompatibility with current health care practices and reimbursement issues. Future projects should therefore focus more on the deployment of assistive technology, and appropriate business plans and scenarios need to be developed for bringing these technologies to the market. Looking to the future of the implementation of assistive technology in general, Peterson et al [<xref ref-type="bibr" rid="ref161">161</xref>] concluded that future assistive technologies would be more integrated into the environment, combined with ambient and intelligent technologies, the potential of cloud computing, and the Internet of Things (a global network of physical objects that contain embedded technology to communicate and sense or interact with their internal states or the external environment). Assistive technologies will also become more personalized to individual needs and user requirements. These developments, however, will bring new challenges (see below).</p>
        <p>Ethical issues: Many ethical issues were addressed by authors in the introduction of their papers, but less were described in the description of the results. With regard to assistive technologies in dementia, several authors stressed that ethical issues were not in the first place related to the technologies themselves but rather to how people use them. Ethical issues that were often described in this field are the dilemmas between autonomy and risk versus privacy reduction and increased safety and difficulties obtaining informed consent when persons with dementia do not understand or are not aware of the presence of the technology.</p>
      </sec>
      <sec>
        <title>The Identified Challenges</title>
        <p>We identified several challenges for research into the selected research topics in the next few years.</p>
        <p>Challenges in the development of assistive technology include how to develop these technologies in a way that meets individual variations in needs and abilities of persons with dementia, so that they really help to maintain autonomy, provide meaningful activities, and promote social inclusion. Another challenge is how to develop assistive technologies that address the emotional state of persons with dementia during everyday tasks [<xref ref-type="bibr" rid="ref41">41</xref>]. A challenge in the field of health care technology supporting organizational systems and services in dementia care is to integrate the technology into the built environment, such as lighting, floor coverings, and improved way-finding [<xref ref-type="bibr" rid="ref42">42</xref>,<xref ref-type="bibr" rid="ref43">43</xref>], and into the routine health care, for example, by using ICT in the clinical assessment of cognitive, behavioral, and physical functioning of persons with dementia [<xref ref-type="bibr" rid="ref44">44</xref>].</p>
        <p>A challenge regarding usability lies in identifying those applications that have particular relevance for people living with dementia. A reiterated theme out of each of the literature reviews is the essential requirement to involve those with a diagnosis of dementia in identifying which needs technologies should meet, and in the development and usability testing of technology that is intended for people with dementia.</p>
        <p>A challenge in effectiveness and cost-effectiveness research is to conduct methodologically sound scientific research in this field comparing assistive technology with care as usual. To conduct RCTs with large enough samples may be difficult because the assistive technologies may be expensive or it may be invasive to have them implemented in one’s home, for example, with sensors and cameras installed. Another challenge is to select adequate outcome measures that reflect the results of assistive technology interaction [<xref ref-type="bibr" rid="ref161">161</xref>]. A third challenge is rooted in the fact that technology is an ever-moving target [<xref ref-type="bibr" rid="ref20">20</xref>]. Everyday devices are continually developing with newer technologies coming to market, rendering evaluation of any one device obsolete within a short time frame. There is a clear need for new methods of rapid technology appraisal and evaluation to inform deployment [<xref ref-type="bibr" rid="ref162">162</xref>].</p>
        <p>Regarding deployment, the challenge lies in overcoming the barriers that will be faced as a result of the expected further integration of technologies within the built environment. These are challenges concerning, for example, data storage, system integrity, privacy and security, networked architecture, and service provision. Furthermore, having a good source of trusted and high-quality information on assistive and health care technologies to inform relevant stakeholders who may further implement them will be another challenge.</p>
        <p>As for ethical issues, a challenge will be obtaining informed consent of participants with dementia for research on assistive technologies. This may have to do with difficulties in understanding what the technologies encompass and a lack of awareness over time of the presence and use of technology, or with data that are collected on people with dementia. Another challenge is to ensure that ethical issues are considered an important topic for researchers to include in their evaluation of assistive technologies.</p>
      </sec>
      <sec>
        <title>Limitations</title>
        <p>The interpretation of assistive technologies used for the evidence reviews embraced bespoke devices developed to support persons living with dementia to manage their everyday life and participate in meaningful and enjoyable activities and health care technology. However, these reviews can only provide a retrospective snapshot of what has been researched rather than reflecting the current picture and what the future might hold. Also, the literature reviews were limited to (systematic) reviews rather than single studies because we aimed to get a global overview of the state of art. Furthermore, we did not consult persons living with dementia regarding their experiences and priorities.</p>
      </sec>
      <sec>
        <title>Recommendations</title>
        <p>Our work underscored the challenge of determining the current “state of the art” in technology development and deployment given the dynamic definitions and various understandings of what assistive technologies are. This complexity is magnified when assistive technologies are situated within dementia. Nevertheless, based on the current literature, we recommend the following actions for development, usability, effectiveness and cost-effectiveness research, deployment, and ethics of assistive and health technologies across Europe and suggest that they are included in national and international calls for funding and assistive technology research programs in the coming decade (<xref ref-type="boxed-text" rid="box1">Textboxes 1</xref>-<xref ref-type="boxed-text" rid="box4">4</xref>).</p>
        <boxed-text id="box1" position="float">
          <title>Actions to improve the development and usability of assistive technologies.</title>
          <list list-type="bullet">
            <list-item>
              <p>Persons with mild-to-moderate dementia or their supporters must be involved in all projects that aim to develop or test technologies for their ultimate benefit; this must be a prerequisite for project funding.</p>
            </list-item>
            <list-item>
              <p>Researchers involved in such technology development for persons with dementia must have adequate knowledge of dementia and, if not, receive specific training and support to enable full and meaningful engagement with persons with dementia; this should also be a prerequisite for funding.</p>
            </list-item>
            <list-item>
              <p>Steps must be taken to ensure that unnecessary replication of technology development that is proven unhelpful or ineffective does not occur.</p>
            </list-item>
          </list>
        </boxed-text>
        <boxed-text id="box2" position="float">
          <title>Actions regarding research into the effectiveness of assistive technologies.</title>
          <p>Research into the effectiveness of assistive technologies should move beyond explorative studies and include more and larger RCTs.</p>
          <p>The focus should be on how technological services succeed in addressing individual needs of persons with dementia, as the population is heterogeneous and many face comorbid conditions.</p>
          <p>Many different outcome measures are used in effect studies, making it difficult to synthesize the results of individual studies. Consensus on the use of outcome measures in this field is recommended [<xref ref-type="bibr" rid="ref163">163</xref>]. Also, other designs such as randomized block designs with sufficient power can be considered to study these effects.</p>
          <p>Research is needed on the cost-effectiveness of assistive technologies.</p>
          <p>New methods of technology evaluation are required so that the results can be rapidly obtained and translated into practice, such as logging use and electronic ecological momentary assessments.</p>
        </boxed-text>
        <boxed-text id="box3" position="float">
          <title>Actions regarding the deployment of assistive technologies.</title>
          <p>Persons living with dementia and those involved in providing treatment and support need clear information about what already exists, for whom, and in what situations (eg, via the websites of national Alzheimer associations). They also need examples of how everyday devices can be used effectively by persons with dementia to enable appropriate deployment.</p>
          <p>The benefits of new forms of technologies for persons with dementia have to be considered before they are brought on the market or disseminated; examples include robots for care and companionship and ubiquitous computing in the home and in society.</p>
        </boxed-text>
        <boxed-text id="box4" position="float">
          <title>Actions regarding ethics in using assistive technologies.</title>
          <p>Our review has demonstrated 3 important issues of relevance to researchers in this domain that ask for the following action:</p>
          <p>There should be greater consistency among researchers regarding the terms used to describe ethical issues. This will facilitate the comparison of findings and recommendations.</p>
          <p>Guidelines on ethical issues related to assistive technology use by or for people with dementia are available [<xref ref-type="bibr" rid="ref164">164</xref>,<xref ref-type="bibr" rid="ref165">165</xref>]. However, they are not widely applied in research exploring the role of assistive technology for community-dwelling persons with dementia. Researchers working in this area are advised to review and engage with these guidelines that provide a structured approach to addressing ethical dilemmas in the context of dementia care [<xref ref-type="bibr" rid="ref165">165</xref>] rather than simply highlighting such ethical dilemmas. This should ensure that not only the conduct of the research complies with ethical principles but that the future use of devices also promotes ethical practice.</p>
          <p>Researchers should strive to ensure that emerging reflection and findings on the ethical use of assistive technologies reach the general public, persons with dementia, informal carers, and health care professionals, and that for this wider dissemination, terms and explanations are understandable and meaningful to these targeted groups.</p>
        </boxed-text>
      </sec>
      <sec>
        <title>Conclusions</title>
        <p>Although this study shows that further research into the development and evaluation of assistive technologies for persons with dementia is needed, it also shows that they are enthusiastic about using technologies to remain their independency, that assistive technologies can improve cognition, mood, and social functioning and decrease service use, and that the use of technology is expected to improve with the increase in computer literacy and level of education, which will be the case in future generations of older people. It is therefore recommended that policy makers, care insurers, and care providers together with technology enterprises and researchers prepare strategies for the deployment of affordable assistive technologies in different care settings, to ensure that future generations of persons with dementia can derive benefit from this.</p>
      </sec>
    </sec>
  </body>
  <back>
    <glossary>
      <title>Abbreviations</title>
      <def-list>
        <def-item>
          <term id="abb1">AALA</term>
          <def>
            <p>Ambient Assisted Living Association</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb2">CeHRes</term>
          <def>
            <p>Centre for eHealth Research and Disease Management</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb3">GPS</term>
          <def>
            <p>Global Positioning System</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb4">HCD</term>
          <def>
            <p>human-centered design</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb5">HSTA</term>
          <def>
            <p>health services or technology assessment</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb6">HTA</term>
          <def>
            <p>health technology assessment</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb7">ICT</term>
          <def>
            <p>information and communication technology</p>
          </def>
        </def-item>
        <def-item>
          <term id="abb8">RCT</term>
          <def>
            <p>randomized controlled trial</p>
          </def>
        </def-item>
      </def-list>
    </glossary>
    <fn-group>
      <fn fn-type="conflict">
        <p>None declared.</p>
      </fn>
    </fn-group>
    <ref-list>
      <ref id="ref1">
        <label>1</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Prince</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Albanese</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Guerchet</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Prina</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <source>Alz.co</source>  
        <year>2014</year>  
        <publisher-loc>London, UK</publisher-loc>
        <publisher-name>Alzheimer's Disease International</publisher-name>
        <comment>World Alzheimer's Report 2014: Dementia and Risk Reduction: An analysis of protective and modifiable factors 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://www.alz.co.uk/research/WorldAlzheimerReport2014.pdf">https://www.alz.co.uk/research/WorldAlzheimerReport2014.pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6n4mbNcgX"/></comment> </nlm-citation>
      </ref>
      <ref id="ref2">
        <label>2</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Prince</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Wimo</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Guerchet</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>All</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Wu</surname>
            <given-names>Y</given-names>
          </name>
          <name name-style="western">
            <surname>Prina</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <source>Alz.co</source>  
        <year>2015</year>  
        <publisher-loc>London, UK</publisher-loc>
        <publisher-name>Alzheimer's Disease International</publisher-name>
        <comment>World Alzheimer's Report 2015: The Global Impact of Dementia: An analysis of prevalence, incidence, cost and trends 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.alz.co.uk/research/WorldAlzheimerReport2015.pdf">http://www.alz.co.uk/research/WorldAlzheimerReport2015.pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6n4msmO3n"/></comment> </nlm-citation>
      </ref>
      <ref id="ref3">
        <label>3</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Prince</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Prina</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Guerchet</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <source>Alz.co</source>  
        <year>2013</year>  
        <access-date>2016-12-28</access-date>
        <publisher-loc>London, UK</publisher-loc>
        <publisher-name>Alzheimer's Disease International</publisher-name>
        <comment>World Alzheimer's Report 2013: Journey of Caring: An analysis of long-term care for dementia 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://www.alz.co.uk/research/WorldAlzheimerReport2013.pdf">https://www.alz.co.uk/research/WorldAlzheimerReport2013.pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6n4nG6Z9x"/></comment> </nlm-citation>
      </ref>
      <ref id="ref4">
        <label>4</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Prince</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Bryce</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Ferri</surname>
            <given-names>C</given-names>
          </name>
        </person-group>
        <source>Alz.co</source>  
        <year>2011</year>  
        <access-date>2016-10-12</access-date>
        <publisher-loc>London, UK</publisher-loc>
        <publisher-name>Alzheimer's Disease International</publisher-name>
        <comment>World Alzheimer's Report 2011: The benefits of early diagnosis and intervention 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.alz.co.uk/research/WorldAlzheimerReport2011.pdf">http://www.alz.co.uk/research/WorldAlzheimerReport2011.pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lBbNqxOb"/></comment> </nlm-citation>
      </ref>
      <ref id="ref5">
        <label>5</label>
        <nlm-citation citation-type="book">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Marshall</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <source>State of the art in dementia care</source>  
        <year>1997</year>  
        <publisher-loc>London, UK</publisher-loc>
        <publisher-name>Centre For Policy on Ageing</publisher-name></nlm-citation>
      </ref>
      <ref id="ref6">
        <label>6</label>
        <nlm-citation citation-type="web">
        <source>ATiA</source>  
        <access-date>2016-10-15</access-date>
        <comment>What is AT? 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.atia.org/at-resources/what-is-at/">http://www.atia.org/at-resources/what-is-at/</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHhBGu7u"/></comment> </nlm-citation>
      </ref>
      <ref id="ref7">
        <label>7</label>
        <nlm-citation citation-type="web">
        <source>ISO</source>  
        <year>2011</year>  
        <access-date>2016-10-15</access-date>
        <comment>ISO 9999:2011. Assistive products for persons with disability -- Classification and terminology 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.iso.org/iso/catalogue_detail.htm?csnumber=50982">http://www.iso.org/iso/catalogue_detail.htm?csnumber=50982</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHhgafkj"/></comment> </nlm-citation>
      </ref>
      <ref id="ref8">
        <label>8</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Andrich</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Mathiassen</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Hoogerwerf</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Gelderblom</surname>
            <given-names>G</given-names>
          </name>
        </person-group>
        <article-title>Service delivery systems for assistive technology in Europe: An AAATE/EASTIN position paper</article-title>
        <source>Technol Disabil</source>  
        <year>2013</year>  
        <month>08</month>  
        <volume>25</volume>  
        <issue>3</issue>  
        <fpage>127</fpage>  
        <lpage>146</lpage>  
        <pub-id pub-id-type="doi">10.3233/TAD-130381</pub-id></nlm-citation>
      </ref>
      <ref id="ref9">
        <label>9</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Van der Roest</surname>
            <given-names>HG</given-names>
          </name>
          <name name-style="western">
            <surname>Meiland</surname>
            <given-names>FJ</given-names>
          </name>
          <name name-style="western">
            <surname>Comijs</surname>
            <given-names>HC</given-names>
          </name>
          <name name-style="western">
            <surname>Derksen</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Jansen</surname>
            <given-names>AP</given-names>
          </name>
          <name name-style="western">
            <surname>van Hout</surname>
            <given-names>HP</given-names>
          </name>
          <name name-style="western">
            <surname>Jonker</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Dröes</surname>
            <given-names>RM</given-names>
          </name>
        </person-group>
        <article-title>What do community-dwelling people with dementia need? A survey of those who are known to care and welfare services</article-title>
        <source>Int Psychogeriatr</source>  
        <year>2009</year>  
        <month>10</month>  
        <volume>21</volume>  
        <issue>5</issue>  
        <fpage>949</fpage>  
        <lpage>65</lpage>  
        <pub-id pub-id-type="doi">10.1017/S1041610209990147</pub-id>
        <pub-id pub-id-type="medline">19602305</pub-id>
        <pub-id pub-id-type="pii">S1041610209990147</pub-id></nlm-citation>
      </ref>
      <ref id="ref10">
        <label>10</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Miranda-Castillo</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Woods</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Orrell</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>The needs of people with dementia living at home from user, caregiver and professional perspectives: a cross-sectional survey</article-title>
        <source>BMC Health Serv Res</source>  
        <year>2013</year>  
        <month>02</month>  
        <day>04</day>  
        <volume>13</volume>  
        <fpage>43</fpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://bmchealthservres.biomedcentral.com/articles/10.1186/1472-6963-13-43"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1186/1472-6963-13-43</pub-id>
        <pub-id pub-id-type="medline">23379786</pub-id>
        <pub-id pub-id-type="pii">1472-6963-13-43</pub-id>
        <pub-id pub-id-type="pmcid">PMC3568411</pub-id></nlm-citation>
      </ref>
      <ref id="ref11">
        <label>11</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Topo</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Technology studies to meet the needs of people with dementia and their caregivers: a literature review</article-title>
        <source>J Appl Geront</source>  
        <year>2008</year>  
        <month>10</month>  
        <day>01</day>  
        <volume>28</volume>  
        <issue>1</issue>  
        <fpage>5</fpage>  
        <lpage>37</lpage>  
        <pub-id pub-id-type="doi">10.1177/0733464808324019</pub-id></nlm-citation>
      </ref>
      <ref id="ref12">
        <label>12</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Rauhala</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Topo</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Independent living, technology and ethics</article-title>
        <source>Technol Disabil</source>  
        <year>2003</year>  
        <volume>15</volume>  
        <issue>3</issue>  
        <fpage>205</fpage>  
        <lpage>14</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://content.iospress.com/articles/technology-and-disability/tad00134"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref13">
        <label>13</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Lauriks</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Reinersmann</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>van der Roest</surname>
            <given-names>HG</given-names>
          </name>
          <name name-style="western">
            <surname>Meiland</surname>
            <given-names>FJ</given-names>
          </name>
          <name name-style="western">
            <surname>Davies</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Moelaert</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Mulvenna</surname>
            <given-names>MD</given-names>
          </name>
          <name name-style="western">
            <surname>Nugent</surname>
            <given-names>CD</given-names>
          </name>
          <name name-style="western">
            <surname>Dröes</surname>
            <given-names>RM</given-names>
          </name>
        </person-group>
        <article-title>Review of ICT-based services for identified unmet needs in people with dementia</article-title>
        <source>Ageing Res Rev</source>  
        <year>2007</year>  
        <month>10</month>  
        <volume>6</volume>  
        <issue>3</issue>  
        <fpage>223</fpage>  
        <lpage>46</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.arr.2007.07.002</pub-id>
        <pub-id pub-id-type="medline">17869590</pub-id>
        <pub-id pub-id-type="pii">S1568-1637(07)00037-2</pub-id></nlm-citation>
      </ref>
      <ref id="ref14">
        <label>14</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Robinson</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Brittain</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Lindsay</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Jackson</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Olivier</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Keeping In Touch Everyday (KITE) project: developing assistive technologies with people with dementia and their carers to promote independence</article-title>
        <source>Int Psychogeriatr</source>  
        <year>2009</year>  
        <month>06</month>  
        <volume>21</volume>  
        <issue>3</issue>  
        <fpage>494</fpage>  
        <lpage>502</lpage>  
        <pub-id pub-id-type="doi">10.1017/S1041610209008448</pub-id>
        <pub-id pub-id-type="medline">19193255</pub-id>
        <pub-id pub-id-type="pii">S1041610209008448</pub-id></nlm-citation>
      </ref>
      <ref id="ref15">
        <label>15</label>
        <nlm-citation citation-type="book">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Woolham</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <source>Safe at home: the effectiveness of assistive technology in supporting the independence of people with dementia: the safe at home project</source>  
        <year>2005</year>  
        <publisher-loc>London</publisher-loc>
        <publisher-name>Hawker</publisher-name></nlm-citation>
      </ref>
      <ref id="ref16">
        <label>16</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Gitlin</surname>
            <given-names>LN</given-names>
          </name>
          <name name-style="western">
            <surname>Winter</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Dennis</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Assistive devices caregivers use and find helpful to manage problem behaviors of dementia</article-title>
        <source>Gerontechnology</source>  
        <year>2010</year>  
        <volume>9</volume>  
        <issue>3</issue>  
        <fpage>408</fpage>  
        <lpage>414</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/25429254"/>
        </comment>  
        <pub-id pub-id-type="doi">10.4017/gt.2010.09.03.006.00</pub-id>
        <pub-id pub-id-type="medline">25429254</pub-id>
        <pub-id pub-id-type="pmcid">PMC4241973</pub-id></nlm-citation>
      </ref>
      <ref id="ref17">
        <label>17</label>
        <nlm-citation citation-type="book">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Evans</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Brown</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Coughlan</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Lawson</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Craven</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <person-group person-group-type="editor">
          <name name-style="western">
            <surname>Kurosu</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>A Systematic Review of Dementia Focused Assistive Technology</article-title>
        <source>Human-Computer Interaction: Interaction Technologies</source>  
        <year>2015</year>  
        <publisher-loc>Cham</publisher-loc>
        <publisher-name>Springer</publisher-name></nlm-citation>
      </ref>
      <ref id="ref18">
        <label>18</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Fleming</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Sum</surname>
            <given-names>S</given-names>
          </name>
        </person-group>
        <article-title>Empirical studies on the effectiveness of assistive technology in the care of people with dementia: a systematic review</article-title>
        <source>J Assistive Technologies</source>  
        <year>2014</year>  
        <month>03</month>  
        <day>12</day>  
        <volume>8</volume>  
        <issue>1</issue>  
        <fpage>14</fpage>  
        <lpage>34</lpage>  
        <pub-id pub-id-type="doi">10.1108/JAT-09-2012-0021</pub-id></nlm-citation>
      </ref>
      <ref id="ref19">
        <label>19</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Bowes</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Dawson</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Greasley-Adams</surname>
            <given-names>C</given-names>
          </name>
        </person-group>
        <source>Dementia.stir</source>  
        <publisher-name>Dementia Services Development Centre, University of Stirling</publisher-name>
        <comment>Literature review: the cost effectiveness of assistive technology in supporting people with dementia. Report to the Dementia Services Development Trust 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://dementia.stir.ac.uk/system/files/filedepot/1/the_cost_effectiveness_of_assistive_technology_in_supporting_people_with_dementia_october_13_1.pdf">http://dementia.stir.ac.uk/system/files/filedepot/1/the_cost_effectiveness_of_assistive_technology_in_supporting_people_with_dementia_october_13_1.pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lBcWFl9v"/></comment> </nlm-citation>
      </ref>
      <ref id="ref20">
        <label>20</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Knapp</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Barlow</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Comras-Herrera</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Damant</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Freddolino</surname>
            <given-names>PP</given-names>
          </name>
          <name name-style="western">
            <surname>Hamblin</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Hu</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Lorenz</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Perkins</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Rehill</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <source>Eprints.lse</source>  
        <year>2015</year>  
        <access-date>2016-10-16</access-date>
        <comment>The case for investment in technology to manage the global costs of dementia 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://eprints.lse.ac.uk/66482/1/__lse.ac.uk_storage_LIBRARY_Secondary_libfile_shared_repository_Content_LSEE_The%20case%20for%20investment%20in%20technology.pdf">http://eprints.lse.ac.uk/66482/1/__lse.ac.uk_storage_LIBRARY_Secondary_libfile_shared_repository_Content_LSEE_The%20case%20for%20investment%20in%20technology.pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHhxiZMP"/></comment> </nlm-citation>
      </ref>
      <ref id="ref21">
        <label>21</label>
        <nlm-citation citation-type="web">
        <source>Alzheimer's Society</source>  
        <year>2014</year>  
        <access-date>2016-10-15</access-date>
        <comment>Dementia-friendly technology: Delivering the national dementia challenge 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://www.alzheimers.org.uk/site/scripts/download_info.php?fileID=1921">https://www.alzheimers.org.uk/site/scripts/download_info.php?fileID=1921</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHiN7VhX"/></comment> </nlm-citation>
      </ref>
      <ref id="ref22">
        <label>22</label>
        <nlm-citation citation-type="web">
        <source>Interdem</source>  
        <access-date>2016-10-15</access-date>
        <comment>About Interdem 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://interdem.org/">http://interdem.org/</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHiU0Gx2"/></comment> </nlm-citation>
      </ref>
      <ref id="ref23">
        <label>23</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Gibson</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Newton</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Pritchard</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Finch</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Brittain</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Robinson</surname>
            <given-names>L</given-names>
          </name>
        </person-group>
        <article-title>The provision of assistive technology products and services for people with dementia in the United Kingdom</article-title>
        <source>Dementia</source>  
        <year>2014</year>  
        <month>05</month>  
        <volume>15</volume>  
        <issue>4</issue>  
        <fpage>681</fpage>  
        <lpage>701</lpage>  
        <pub-id pub-id-type="doi">10.1177/1471301214532643</pub-id>
        <pub-id pub-id-type="medline">24803646</pub-id>
        <pub-id pub-id-type="pii">1471301214532643</pub-id></nlm-citation>
      </ref>
      <ref id="ref24">
        <label>24</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Span</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Hettinga</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Vernooij-Dassen</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Eefsting</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Smits</surname>
            <given-names>C</given-names>
          </name>
        </person-group>
        <article-title>Involving people with dementia in the development of supportive IT applications: a systematic review</article-title>
        <source>Ageing Res Rev</source>  
        <year>2013</year>  
        <month>03</month>  
        <volume>12</volume>  
        <issue>2</issue>  
        <fpage>535</fpage>  
        <lpage>51</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.arr.2013.01.002</pub-id>
        <pub-id pub-id-type="medline">23318684</pub-id>
        <pub-id pub-id-type="pii">S1568-1637(13)00003-2</pub-id></nlm-citation>
      </ref>
      <ref id="ref25">
        <label>25</label>
        <nlm-citation citation-type="book">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>De Filippis</surname>
            <given-names>ML</given-names>
          </name>
          <name name-style="western">
            <surname>Craven</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Dening</surname>
            <given-names>T</given-names>
          </name>
        </person-group>
        <person-group person-group-type="editor">
          <name name-style="western">
            <surname>Pecchia</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Chen</surname>
            <given-names>LL</given-names>
          </name>
          <name name-style="western">
            <surname>Nugent</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Bravo</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Informal carer role in the personalisation of assistive solutions connected to aspirations of people with dementia</article-title>
        <source>Ambient Assisted Living and Daily Activities</source>  
        <year>2014</year>  
        <publisher-loc>Cham</publisher-loc>
        <publisher-name>Springer International Publishing</publisher-name></nlm-citation>
      </ref>
      <ref id="ref26">
        <label>26</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Von Kutzleben</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Schmid</surname>
            <given-names>W</given-names>
          </name>
          <name name-style="western">
            <surname>Halek</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Holle</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Bartholomeyczik</surname>
            <given-names>S</given-names>
          </name>
        </person-group>
        <article-title>Community-dwelling persons with dementia: what do they need? What do they demand? What do they do? A systematic review on the subjective experiences of persons with dementia</article-title>
        <source>Aging Ment Health</source>  
        <year>2012</year>  
        <volume>16</volume>  
        <issue>3</issue>  
        <fpage>378</fpage>  
        <lpage>90</lpage>  
        <pub-id pub-id-type="doi">10.1080/13607863.2011.614594</pub-id>
        <pub-id pub-id-type="medline">22250961</pub-id></nlm-citation>
      </ref>
      <ref id="ref27">
        <label>27</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Miller</surname>
            <given-names>LM</given-names>
          </name>
          <name name-style="western">
            <surname>Whitlatch</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Lyons</surname>
            <given-names>K</given-names>
          </name>
        </person-group>
        <article-title>Shared decision-making in dementia: a review of patient and family carer involvement</article-title>
        <source>Dementia</source>  
        <year>2014</year>  
        <month>11</month>  
        <day>03</day>  
        <volume>15</volume>  
        <issue>5</issue>  
        <fpage>1141</fpage>  
        <lpage>57</lpage>  
        <pub-id pub-id-type="doi">10.1177/1471301214555542</pub-id>
        <pub-id pub-id-type="medline">25370075</pub-id>
        <pub-id pub-id-type="pii">1471301214555542</pub-id></nlm-citation>
      </ref>
      <ref id="ref28">
        <label>28</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Whitlatch</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Menne</surname>
            <given-names>H</given-names>
          </name>
        </person-group>
        <article-title>Don't forget about me! Decision making by people with dementia</article-title>
        <source>Generations</source>  
        <year>2009</year>  
        <volume>33</volume>  
        <issue>1</issue>  
        <fpage>66</fpage>  
        <lpage>73</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.ingentaconnect.com/content/asag/gen/2009/00000033/00000001/art00011#expand/collapse"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref29">
        <label>29</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Smith</surname>
            <given-names>SK</given-names>
          </name>
          <name name-style="western">
            <surname>Mountain</surname>
            <given-names>GA</given-names>
          </name>
        </person-group>
        <article-title>New forms of information and communication technology (ICT) and the potential to facilitate social and leisure activity for people living with dementia</article-title>
        <source>IJCIH</source>  
        <year>2012</year>  
        <volume>1</volume>  
        <issue>4</issue>  
        <fpage>332</fpage>  
        <lpage>345</lpage>  
        <pub-id pub-id-type="doi">10.1504/IJCIH.2012.051810</pub-id></nlm-citation>
      </ref>
      <ref id="ref30">
        <label>30</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Van Gemert-Pijnen</surname>
            <given-names>JE</given-names>
          </name>
          <name name-style="western">
            <surname>Nijland</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>van Limburg</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Ossebaard</surname>
            <given-names>HC</given-names>
          </name>
          <name name-style="western">
            <surname>Kelders</surname>
            <given-names>SM</given-names>
          </name>
          <name name-style="western">
            <surname>Eysenbach</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Seydel</surname>
            <given-names>ER</given-names>
          </name>
        </person-group>
        <article-title>A holistic framework to improve the uptake and impact of eHealth technologies</article-title>
        <source>J Med Internet Res</source>  
        <year>2011</year>  
        <month>12</month>  
        <day>05</day>  
        <volume>13</volume>  
        <issue>4</issue>  
        <fpage>e111</fpage>  
        <pub-id pub-id-type="doi">10.2196/jmir.1672</pub-id>
        <pub-id pub-id-type="medline">22155738</pub-id>
        <pub-id pub-id-type="pii">v13i4e111</pub-id>
        <pub-id pub-id-type="pmcid">PMC3278097</pub-id></nlm-citation>
      </ref>
      <ref id="ref31">
        <label>31</label>
        <nlm-citation citation-type="book">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Beyer</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Holtzblatt</surname>
            <given-names>K</given-names>
          </name>
        </person-group>
        <source>Contextual design: defining customer-centered systems</source>  
        <year>1998</year>  
        <publisher-loc>San Francisco, Calif</publisher-loc>
        <publisher-name>Morgan Kaufmann Publishers</publisher-name></nlm-citation>
      </ref>
      <ref id="ref32">
        <label>32</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Faife</surname>
            <given-names>D</given-names>
          </name>
        </person-group>
        <article-title>Assistive technology in dementia care: have we reached consensus?</article-title>
        <source>J Dem Care</source>  
        <year>2006</year>  
        <month>11</month>  
        <volume>14</volume>  
        <issue>6</issue>  
        <fpage>14</fpage>  
        <lpage>5</lpage> </nlm-citation>
      </ref>
      <ref id="ref33">
        <label>33</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Span</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <year>2016</year>  
        <publisher-loc>Amsterdam</publisher-loc>
        <publisher-name>Vrije Universiteit</publisher-name>
        <comment>Developing an interactive web tool to facilitate shared decision-making in dementia care networks: a participatory journey 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://hdl.handle.net/1871/54018">http://hdl.handle.net/1871/54018</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6n4tyNNHl"/></comment> </nlm-citation>
      </ref>
      <ref id="ref34">
        <label>34</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Robinson</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Hutchings</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Dickinson</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Corner</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Beyer</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Finch</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Hughes</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Vanoli</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Ballard</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Bond</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Effectiveness and acceptability of non-pharmacological interventions to reduce wandering in dementia: a systematic review</article-title>
        <source>Int J Geriatr Psychiatry</source>  
        <year>2007</year>  
        <month>01</month>  
        <volume>22</volume>  
        <issue>1</issue>  
        <fpage>9</fpage>  
        <lpage>22</lpage>  
        <pub-id pub-id-type="doi">10.1002/gps.1643</pub-id>
        <pub-id pub-id-type="medline">17096455</pub-id></nlm-citation>
      </ref>
      <ref id="ref35">
        <label>35</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Orpwood</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Bjørneby</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Hagen</surname>
            <given-names>I</given-names>
          </name>
          <name name-style="western">
            <surname>Mäki</surname>
            <given-names>O</given-names>
          </name>
          <name name-style="western">
            <surname>Faulkner</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Topo</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>User involvement in dementia product development</article-title>
        <source>Dementia</source>  
        <year>2004</year>  
        <month>10</month>  
        <day>01</day>  
        <volume>3</volume>  
        <issue>3</issue>  
        <fpage>263</fpage>  
        <lpage>79</lpage>  
        <pub-id pub-id-type="doi">10.1177/1471301204045160</pub-id></nlm-citation>
      </ref>
      <ref id="ref36">
        <label>36</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Evans</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Orpwood</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Adlam</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Chad</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Evaluation of an enabling smart flat for people with dementia</article-title>
        <source>J Dem Care</source>  
        <year>2007</year>  
        <month>11</month>  
        <volume>15</volume>  
        <issue>6</issue>  
        <fpage>33</fpage>  
        <lpage>7</lpage> </nlm-citation>
      </ref>
      <ref id="ref37">
        <label>37</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Meiland</surname>
            <given-names>FJ</given-names>
          </name>
          <name name-style="western">
            <surname>Hattink</surname>
            <given-names>BJ</given-names>
          </name>
          <name name-style="western">
            <surname>Overmars-Marx</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>de Boer</surname>
            <given-names>ME</given-names>
          </name>
          <name name-style="western">
            <surname>Jedlitschka</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Ebben</surname>
            <given-names>PW</given-names>
          </name>
          <name name-style="western">
            <surname>Stalpers-Croeze</surname>
            <given-names>II</given-names>
          </name>
          <name name-style="western">
            <surname>Flick</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>van der Leeuw</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Karkowski</surname>
            <given-names>IP</given-names>
          </name>
          <name name-style="western">
            <surname>Dröes</surname>
            <given-names>RM</given-names>
          </name>
        </person-group>
        <article-title>Participation of end users in the design of assistive technology for people with mild to severe cognitive problems; the European Rosetta project</article-title>
        <source>Int Psychogeriatr</source>  
        <year>2014</year>  
        <month>05</month>  
        <volume>26</volume>  
        <issue>5</issue>  
        <fpage>769</fpage>  
        <lpage>79</lpage>  
        <pub-id pub-id-type="doi">10.1017/S1041610214000088</pub-id>
        <pub-id pub-id-type="medline">24507571</pub-id>
        <pub-id pub-id-type="pii">S1041610214000088</pub-id></nlm-citation>
      </ref>
      <ref id="ref38">
        <label>38</label>
        <nlm-citation citation-type="web">
        <source>Alzheimer's Society</source>  
        <access-date>2016-10-15</access-date>
        <comment>Dementia Friendly Communities 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://www.alzheimers.org.uk/dementiafriendlycommunities">https://www.alzheimers.org.uk/dementiafriendlycommunities</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHj6BQHS"/></comment> </nlm-citation>
      </ref>
      <ref id="ref39">
        <label>39</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Nugent</surname>
            <given-names>CD</given-names>
          </name>
          <name name-style="western">
            <surname>Davies</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Donnelly</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Hallberg</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Hariz</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Craig</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Meiland</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Moelaert</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Bengtsson</surname>
            <given-names>JE</given-names>
          </name>
          <name name-style="western">
            <surname>Savenstedt</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Mulvenna</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Dröes</surname>
            <given-names>RM</given-names>
          </name>
        </person-group>
        <article-title>The development of personalised cognitive prosthetics</article-title>
        <source>Conf Proc IEEE Eng Med Biol Soc</source>  
        <year>2008</year>  
        <fpage>787</fpage>  
        <lpage>90</lpage>  
        <pub-id pub-id-type="doi">10.1109/IEMBS.2008.4649270</pub-id>
        <pub-id pub-id-type="medline">19162773</pub-id></nlm-citation>
      </ref>
      <ref id="ref40">
        <label>40</label>
        <nlm-citation citation-type="web">
        <source>Youralcove</source>  
        <access-date>2016-10-16</access-date>
        <comment>Alcove 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.youralcove.com/">http://www.youralcove.com/</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHjDkvFy"/></comment> </nlm-citation>
      </ref>
      <ref id="ref41">
        <label>41</label>
        <nlm-citation citation-type="confproc">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Malhotra</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Yu</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Schröder</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Hoey</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>An exploratory study into the use of an emotionally aware cognitive assistant</article-title>
        <year>2015</year>  
        <conf-name>Proceedings AAAI Workshop on artificial intelligence applied to assitive technologiessmart environments; ; Austin, TX. USA</conf-name>
        <conf-date>2015</conf-date>
        <conf-loc>Austing, Texas, USA</conf-loc></nlm-citation>
      </ref>
      <ref id="ref42">
        <label>42</label>
        <nlm-citation citation-type="web">
        <source>Kings Fund</source>  
        <access-date>2016-10-15</access-date>
        <comment>Environments of care for people with dementia 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.kingsfund.org.uk/projects/enhancing-healing-environment/ehe-in-dementia-care">http://www.kingsfund.org.uk/projects/enhancing-healing-environment/ehe-in-dementia-care</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHjSLhLL"/></comment> </nlm-citation>
      </ref>
      <ref id="ref43">
        <label>43</label>
        <nlm-citation citation-type="web">
        <source>Alzheimer's Society</source>  
        <access-date>2016-10-15</access-date>
        <comment>Dementia Friendly Technology Charter 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://www.alzheimers.org.uk/technologycharter">https://www.alzheimers.org.uk/technologycharter</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHjaxhpF"/></comment> </nlm-citation>
      </ref>
      <ref id="ref44">
        <label>44</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Robert</surname>
            <given-names>PH</given-names>
          </name>
          <name name-style="western">
            <surname>Konig</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Andrieu</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Bremond</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Chemin</surname>
            <given-names>I</given-names>
          </name>
          <name name-style="western">
            <surname>Chung</surname>
            <given-names>PC</given-names>
          </name>
          <name name-style="western">
            <surname>Dartigues</surname>
            <given-names>JF</given-names>
          </name>
          <name name-style="western">
            <surname>Dubois</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Feutren</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Guillemaud</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Kenisberg</surname>
            <given-names>PA</given-names>
          </name>
          <name name-style="western">
            <surname>Nave</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Vellas</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Verhey</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Yesavage</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Mallea</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Recommendations for ICT use in Alzheimer's disease assessment: Monaco CTAD expert meeting</article-title>
        <source>J Nutr Health Aging</source>  
        <year>2013</year>  
        <volume>17</volume>  
        <issue>8</issue>  
        <fpage>653</fpage>  
        <lpage>60</lpage>  
        <pub-id pub-id-type="doi">10.1007/s12603-013-0046-3</pub-id>
        <pub-id pub-id-type="medline">24097018</pub-id></nlm-citation>
      </ref>
      <ref id="ref45">
        <label>45</label>
        <nlm-citation citation-type="web">
        <source>ISO</source>  
        <year>2010</year>  
        <access-date>2016-10-12</access-date>
        <comment>ISO 9241-210:2010. Ergonomics of human-system interaction -- Part 210: Human-centred design for interactive systems 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.iso.org/iso/catalogue_detail.htm?csnumber=52075">http://www.iso.org/iso/catalogue_detail.htm?csnumber=52075</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lCUJ3OE9"/></comment> </nlm-citation>
      </ref>
      <ref id="ref46">
        <label>46</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Meiland</surname>
            <given-names>FJ</given-names>
          </name>
          <name name-style="western">
            <surname>Bouman</surname>
            <given-names>AI</given-names>
          </name>
          <name name-style="western">
            <surname>Sävenstedt</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Bentvelzen</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Davies</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Mulvenna</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Nugent</surname>
            <given-names>CD</given-names>
          </name>
          <name name-style="western">
            <surname>Moelaert</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Hettinga</surname>
            <given-names>ME</given-names>
          </name>
          <name name-style="western">
            <surname>Bengtsson</surname>
            <given-names>JE</given-names>
          </name>
          <name name-style="western">
            <surname>Dröes</surname>
            <given-names>RM</given-names>
          </name>
        </person-group>
        <article-title>Usability of a new electronic assistive device for community-dwelling persons with mild dementia</article-title>
        <source>Aging Ment Health</source>  
        <year>2012</year>  
        <volume>16</volume>  
        <issue>5</issue>  
        <fpage>584</fpage>  
        <lpage>91</lpage>  
        <pub-id pub-id-type="doi">10.1080/13607863.2011.651433</pub-id>
        <pub-id pub-id-type="medline">22360649</pub-id></nlm-citation>
      </ref>
      <ref id="ref47">
        <label>47</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Pot</surname>
            <given-names>AM</given-names>
          </name>
          <name name-style="western">
            <surname>Willemse</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Horjus</surname>
            <given-names>S</given-names>
          </name>
        </person-group>
        <article-title>A pilot study on the use of tracking technology: feasibility, acceptability, and benefits for people in early stages of dementia and their informal caregivers</article-title>
        <source>Aging Ment Health</source>  
        <year>2012</year>  
        <volume>16</volume>  
        <issue>1</issue>  
        <fpage>127</fpage>  
        <lpage>34</lpage>  
        <pub-id pub-id-type="doi">10.1080/13607863.2011.596810</pub-id>
        <pub-id pub-id-type="medline">21780960</pub-id></nlm-citation>
      </ref>
      <ref id="ref48">
        <label>48</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Starkhammar</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Nygard</surname>
            <given-names>L</given-names>
          </name>
        </person-group>
        <article-title>Using a timer device for the stovexperiences of older adults with memory impairment or dementia and their families</article-title>
        <source>Technol Disabil</source>  
        <year>2008</year>  
        <month>08</month>  
        <volume>20</volume>  
        <issue>3</issue>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://content.iospress.com/articles/technology-and-disability/tad00257"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref49">
        <label>49</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Jelcic</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Agostini</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Meneghello</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Bussè</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Parise</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Galano</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Tonin</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Dam</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Cagnin</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>Feasibility and efficacy of cognitive telerehabilitation in early Alzheimer's disease: a pilot study</article-title>
        <source>Clin Interv Aging</source>  
        <year>2014</year>  
        <volume>9</volume>  
        <fpage>1605</fpage>  
        <lpage>11</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://dx.doi.org/10.2147/CIA.S68145"/>
        </comment>  
        <pub-id pub-id-type="doi">10.2147/CIA.S68145</pub-id>
        <pub-id pub-id-type="medline">25284993</pub-id>
        <pub-id pub-id-type="pii">cia-9-1605</pub-id>
        <pub-id pub-id-type="pmcid">PMC4181448</pub-id></nlm-citation>
      </ref>
      <ref id="ref50">
        <label>50</label>
        <nlm-citation citation-type="confproc">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Zaccarelli</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Cirillo</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Passuti</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Annicchiarico</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Barban</surname>
            <given-names>F</given-names>
          </name>
        </person-group>
        <article-title>Computer-based cognitive intervention for dementia Sociable: motivating platform for elderly networking, mental reinforcement and social interaction</article-title>
        <year>2013</year>  
        <month>05</month>  
        <conf-name>3rd International Workshop on Pervasive Computing Paradigms for Mental Health</conf-name>
        <conf-date>May 5, 2013</conf-date>
        <conf-loc>Venice, Italy</conf-loc>
        <pub-id pub-id-type="doi">10.4108/icst.pervasivehealth.2013.252155</pub-id></nlm-citation>
      </ref>
      <ref id="ref51">
        <label>51</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Lee</surname>
            <given-names>GY</given-names>
          </name>
          <name name-style="western">
            <surname>Yip</surname>
            <given-names>CC</given-names>
          </name>
          <name name-style="western">
            <surname>Yu</surname>
            <given-names>EC</given-names>
          </name>
          <name name-style="western">
            <surname>Man</surname>
            <given-names>DW</given-names>
          </name>
        </person-group>
        <article-title>Evaluation of a computer-assisted errorless learning-based memory training program for patients with early Alzheimer's disease in Hong Kong: a pilot study</article-title>
        <source>Clin Interv Aging</source>  
        <year>2013</year>  
        <volume>8</volume>  
        <fpage>623</fpage>  
        <lpage>33</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://dx.doi.org/10.2147/CIA.S45726"/>
        </comment>  
        <pub-id pub-id-type="doi">10.2147/CIA.S45726</pub-id>
        <pub-id pub-id-type="medline">23766638</pub-id>
        <pub-id pub-id-type="pii">cia-8-623</pub-id>
        <pub-id pub-id-type="pmcid">PMC3679968</pub-id></nlm-citation>
      </ref>
      <ref id="ref52">
        <label>52</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Gillespie</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Best</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>O'Neill</surname>
            <given-names>B</given-names>
          </name>
        </person-group>
        <article-title>Cognitive function and assistive technology for cognition: a systematic review</article-title>
        <source>J Int Neuropsychol Soc</source>  
        <year>2012</year>  
        <month>01</month>  
        <volume>18</volume>  
        <issue>1</issue>  
        <fpage>1</fpage>  
        <lpage>19</lpage>  
        <pub-id pub-id-type="doi">10.1017/S1355617711001548</pub-id>
        <pub-id pub-id-type="medline">22152338</pub-id>
        <pub-id pub-id-type="pii">S1355617711001548</pub-id></nlm-citation>
      </ref>
      <ref id="ref53">
        <label>53</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Boman</surname>
            <given-names>IL</given-names>
          </name>
          <name name-style="western">
            <surname>Lundberg</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Starkhammar</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Nygård</surname>
            <given-names>L</given-names>
          </name>
        </person-group>
        <article-title>Exploring the usability of a videophone mock-up for persons with dementia and their significant others</article-title>
        <source>BMC Geriatr</source>  
        <year>2014</year>  
        <month>04</month>  
        <day>16</day>  
        <volume>14</volume>  
        <fpage>49</fpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://bmcgeriatr.biomedcentral.com/articles/10.1186/1471-2318-14-49"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1186/1471-2318-14-49</pub-id>
        <pub-id pub-id-type="medline">24739662</pub-id>
        <pub-id pub-id-type="pii">1471-2318-14-49</pub-id>
        <pub-id pub-id-type="pmcid">PMC4031376</pub-id></nlm-citation>
      </ref>
      <ref id="ref54">
        <label>54</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Roebuck-Spencer</surname>
            <given-names>TM</given-names>
          </name>
          <name name-style="western">
            <surname>Vincent</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Gilliland</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Johnson</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Cooper</surname>
            <given-names>D</given-names>
          </name>
        </person-group>
        <article-title>Initial clinical validation of an embedded performance validity measure within the automated neuropsychological metrics (ANAM)</article-title>
        <source>Arch Clin Neuropsychol</source>  
        <year>2013</year>  
        <month>11</month>  
        <volume>28</volume>  
        <issue>7</issue>  
        <fpage>700</fpage>  
        <lpage>10</lpage>  
        <pub-id pub-id-type="doi">10.1093/arclin/act055</pub-id>
        <pub-id pub-id-type="medline">23887185</pub-id>
        <pub-id pub-id-type="pii">act055</pub-id></nlm-citation>
      </ref>
      <ref id="ref55">
        <label>55</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Petersen</surname>
            <given-names>RC</given-names>
          </name>
          <name name-style="western">
            <surname>Stevens</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Ganguli</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Tangalos</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Cummings</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>DeKosky</surname>
            <given-names>S</given-names>
          </name>
        </person-group>
        <article-title>Practice parameter: early detection of dementia: mild cognitive impairment (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology</article-title>
        <source>Neurology</source>  
        <year>2001</year>  
        <month>05</month>  
        <day>08</day>  
        <volume>56</volume>  
        <issue>9</issue>  
        <fpage>1133</fpage>  
        <lpage>42</lpage>  
        <pub-id pub-id-type="medline">11342677</pub-id></nlm-citation>
      </ref>
      <ref id="ref56">
        <label>56</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Harrell</surname>
            <given-names>KM</given-names>
          </name>
          <name name-style="western">
            <surname>Wilkins</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Connor</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Chodosh</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Telemedicine and the evaluation of cognitive impairment: the additive value of neuropsychological assessment</article-title>
        <source>J Am Med Dir Assoc</source>  
        <year>2014</year>  
        <month>08</month>  
        <volume>15</volume>  
        <issue>8</issue>  
        <fpage>600</fpage>  
        <lpage>6</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.jamda.2014.04.015</pub-id>
        <pub-id pub-id-type="medline">24913209</pub-id>
        <pub-id pub-id-type="pii">S1525-8610(14)00259-X</pub-id></nlm-citation>
      </ref>
      <ref id="ref57">
        <label>57</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Zapata</surname>
            <given-names>BC</given-names>
          </name>
          <name name-style="western">
            <surname>Fernández-Alemán</surname>
            <given-names>JL</given-names>
          </name>
          <name name-style="western">
            <surname>Idri</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Toval</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>Empirical studies on usability of mHealth apps: a systematic literature review</article-title>
        <source>J Med Syst</source>  
        <year>2015</year>  
        <month>02</month>  
        <volume>39</volume>  
        <issue>2</issue>  
        <fpage>1</fpage>  
        <pub-id pub-id-type="doi">10.1007/s10916-014-0182-2</pub-id>
        <pub-id pub-id-type="medline">25600193</pub-id></nlm-citation>
      </ref>
      <ref id="ref58">
        <label>58</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Sun</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Burke</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Mao</surname>
            <given-names>Z</given-names>
          </name>
          <name name-style="western">
            <surname>Chen</surname>
            <given-names>Y</given-names>
          </name>
          <name name-style="western">
            <surname>Chen</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Bai</surname>
            <given-names>Y</given-names>
          </name>
          <name name-style="western">
            <surname>Li</surname>
            <given-names>Y</given-names>
          </name>
          <name name-style="western">
            <surname>Li</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Jia</surname>
            <given-names>W</given-names>
          </name>
        </person-group>
        <article-title>eButton: a wearable computer for health monitoring and personal assistance</article-title>
        <source>Proc Des Autom Conf</source>  
        <year>2014</year>  
        <volume>2014</volume>  
        <fpage>1</fpage>  
        <lpage>6</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/25340176"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1145/2593069.2596678</pub-id>
        <pub-id pub-id-type="medline">25340176</pub-id>
        <pub-id pub-id-type="pmcid">PMC4203446</pub-id></nlm-citation>
      </ref>
      <ref id="ref59">
        <label>59</label>
        <nlm-citation citation-type="confproc">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Bardram</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Hansen</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Mogensen</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Soegaard</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Experiences from Real-World Deployment of Context-Aware Technologies in a Hospital Environment</article-title>
        <source>UbiComp 2006: 8th International Conference on Ubiquitous Computing</source>  
        <year>2006</year>  
        <conf-name>Ubiquitous Computing: 8th International Conference, UbiComp</conf-name>
        <conf-date>September 17-21, 2006</conf-date>
        <conf-loc>Orange County, CA, USA</conf-loc>
        <publisher-loc>UbiComp 2006</publisher-loc>
        <publisher-name>Ubiquitous Computingth International Conference, UbiComp 2006 Orange County, CA, USA. September 17-21, 2006 Proceedings.Berlin, Heidelbergpringer Berlin Heidelberg</publisher-name>
        <fpage>8</fpage>  
        <lpage>86</lpage>  
        <pub-id pub-id-type="doi">10.1007/11853565_22</pub-id></nlm-citation>
      </ref>
      <ref id="ref60">
        <label>60</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Kramer</surname>
            <given-names>B</given-names>
          </name>
        </person-group>
        <article-title>Dementia caregivers in Germany and their acceptance of new technologies for care: the information gap</article-title>
        <source>Public Policy Aging Rep</source>  
        <year>2013</year>  
        <month>12</month>  
        <day>16</day>  
        <volume>24</volume>  
        <issue>1</issue>  
        <fpage>32</fpage>  
        <lpage>34</lpage>  
        <pub-id pub-id-type="doi">10.1093/ppar/prt002</pub-id></nlm-citation>
      </ref>
      <ref id="ref61">
        <label>61</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Hedman</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Nygård</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Almkvist</surname>
            <given-names>O</given-names>
          </name>
          <name name-style="western">
            <surname>Kottorp</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>Amount and type of everyday technology use over time in older adults with cognitive impairment</article-title>
        <source>Scand J Occup Ther</source>  
        <year>2015</year>  
        <month>05</month>  
        <volume>22</volume>  
        <issue>3</issue>  
        <fpage>196</fpage>  
        <lpage>206</lpage>  
        <pub-id pub-id-type="doi">10.3109/11038128.2014.982172</pub-id>
        <pub-id pub-id-type="medline">25580938</pub-id></nlm-citation>
      </ref>
      <ref id="ref62">
        <label>62</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Aloulou</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Mokhtari</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Tiberghien</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Biswas</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Phua</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Kenneth Lin</surname>
            <given-names>JH</given-names>
          </name>
          <name name-style="western">
            <surname>Yap</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Deployment of assistive living technology in a nursing home environment: methods and lessons learned</article-title>
        <source>BMC Med Inform Decis Mak</source>  
        <year>2013</year>  
        <month>04</month>  
        <day>08</day>  
        <volume>13</volume>  
        <fpage>42</fpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/1472-6947-13-42"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1186/1472-6947-13-42</pub-id>
        <pub-id pub-id-type="medline">23565984</pub-id>
        <pub-id pub-id-type="pii">1472-6947-13-42</pub-id>
        <pub-id pub-id-type="pmcid">PMC3691578</pub-id></nlm-citation>
      </ref>
      <ref id="ref63">
        <label>63</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Canini</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Battista</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Della Rosa</surname>
            <given-names>PA</given-names>
          </name>
          <name name-style="western">
            <surname>Catricalà</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Salvatore</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Gilardi</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Castiglioni</surname>
            <given-names>I</given-names>
          </name>
        </person-group>
        <article-title>Computerized neuropsychological assessment in aging: testing efficacy and clinical ecology of different interfaces</article-title>
        <source>Comput Math Methods Med</source>  
        <year>2014</year>  
        <volume>2014</volume>  
        <fpage>804723</fpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://dx.doi.org/10.1155/2014/804723"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1155/2014/804723</pub-id>
        <pub-id pub-id-type="medline">25147578</pub-id>
        <pub-id pub-id-type="pmcid">PMC4131509</pub-id></nlm-citation>
      </ref>
      <ref id="ref64">
        <label>64</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Wood</surname>
            <given-names>E</given-names>
          </name>
        </person-group>
        <article-title>Use of computer input devices by older adults</article-title>
        <source>J Appl Gerontol</source>  
        <year>2005</year>  
        <month>11</month>  
        <day>01</day>  
        <volume>24</volume>  
        <issue>5</issue>  
        <fpage>419</fpage>  
        <lpage>38</lpage>  
        <pub-id pub-id-type="doi">10.1177/0733464805278378</pub-id></nlm-citation>
      </ref>
      <ref id="ref65">
        <label>65</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Tierney</surname>
            <given-names>MC</given-names>
          </name>
          <name name-style="western">
            <surname>Naglie</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Upshur</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Moineddin</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Charles</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Jaakkimainen</surname>
            <given-names>R</given-names>
          </name>
        </person-group>
        <article-title>Feasibility and validity of the self-administered computerized assessment of mild cognitive impairment with older primary care patients</article-title>
        <source>Alzheimer Dis Assoc Disord</source>  
        <year>2014</year>  
        <volume>28</volume>  
        <issue>4</issue>  
        <fpage>311</fpage>  
        <lpage>9</lpage>  
        <pub-id pub-id-type="doi">10.1097/WAD.0000000000000036</pub-id>
        <pub-id pub-id-type="medline">24614274</pub-id></nlm-citation>
      </ref>
      <ref id="ref66">
        <label>66</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Allain</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Foloppe</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Besnard</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Yamaguchi</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Etcharry-Bouyx</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Le</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Nolin</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Richard</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Detecting everyday action deficits in Alzheimer's disease using a nonimmersive virtual reality kitchen</article-title>
        <source>J Int Neuropsychol Soc</source>  
        <year>2014</year>  
        <month>05</month>  
        <volume>20</volume>  
        <issue>5</issue>  
        <fpage>468</fpage>  
        <lpage>77</lpage>  
        <pub-id pub-id-type="doi">10.1017/S1355617714000344</pub-id>
        <pub-id pub-id-type="medline">24785240</pub-id>
        <pub-id pub-id-type="pii">S1355617714000344</pub-id></nlm-citation>
      </ref>
      <ref id="ref67">
        <label>67</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Plancher</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Tirard</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Gyselinck</surname>
            <given-names>V</given-names>
          </name>
          <name name-style="western">
            <surname>Nicolas</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Piolino</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Using virtual reality to characterize episodic memory profiles in amnestic mild cognitive impairment and Alzheimer's disease: influence of active and passive encoding</article-title>
        <source>Neuropsychologia</source>  
        <year>2012</year>  
        <month>04</month>  
        <volume>50</volume>  
        <issue>5</issue>  
        <fpage>592</fpage>  
        <lpage>602</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.neuropsychologia.2011.12.013</pub-id>
        <pub-id pub-id-type="medline">22261400</pub-id>
        <pub-id pub-id-type="pii">S0028-3932(11)00558-6</pub-id></nlm-citation>
      </ref>
      <ref id="ref68">
        <label>68</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Weniger</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Ruhleder</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Lange</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Wolf</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Irle</surname>
            <given-names>E</given-names>
          </name>
        </person-group>
        <article-title>Egocentric and allocentric memory as assessed by virtual reality in individuals with amnestic mild cognitive impairment</article-title>
        <source>Neuropsychologia</source>  
        <year>2011</year>  
        <month>02</month>  
        <volume>49</volume>  
        <issue>3</issue>  
        <fpage>518</fpage>  
        <lpage>27</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.neuropsychologia.2010.12.031</pub-id>
        <pub-id pub-id-type="medline">21185847</pub-id>
        <pub-id pub-id-type="pii">S0028-3932(10)00564-6</pub-id></nlm-citation>
      </ref>
      <ref id="ref69">
        <label>69</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Zygouris</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Giakoumis</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Votis</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Doumpoulakis</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Ntovas</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Segkouli</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Karagiannidis</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Tzovaras</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Tsolaki</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Can a virtual reality cognitive training application fulfill a dual role? Using the virtual supermarket cognitive training application as a screening tool for mild cognitive impairment</article-title>
        <source>J Alzheimers Dis</source>  
        <year>2015</year>  
        <volume>44</volume>  
        <issue>4</issue>  
        <fpage>1333</fpage>  
        <lpage>47</lpage>  
        <pub-id pub-id-type="doi">10.3233/JAD-141260</pub-id>
        <pub-id pub-id-type="medline">25428251</pub-id>
        <pub-id pub-id-type="pii">B1067J5440771V8H</pub-id></nlm-citation>
      </ref>
      <ref id="ref70">
        <label>70</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Hofmann</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Rösler</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Schwarz</surname>
            <given-names>W</given-names>
          </name>
          <name name-style="western">
            <surname>Müller-Spahn</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Kräuchi</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Hock</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Seifritz</surname>
            <given-names>E</given-names>
          </name>
        </person-group>
        <article-title>Interactive computer-training as a therapeutic tool in Alzheimer's disease</article-title>
        <source>Compr Psychiatry</source>  
        <year>2003</year>  
        <volume>44</volume>  
        <issue>3</issue>  
        <fpage>213</fpage>  
        <lpage>9</lpage>  
        <pub-id pub-id-type="doi">10.1016/S0010-440X(03)00006-3</pub-id>
        <pub-id pub-id-type="medline">12764709</pub-id>
        <pub-id pub-id-type="pii">S0010440X03000063</pub-id></nlm-citation>
      </ref>
      <ref id="ref71">
        <label>71</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Lund</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>Measuring usability with the USE questionnaire</article-title>
        <source>Usability Interface</source>  
        <year>2001</year>  
        <volume>8</volume>  
        <issue>2</issue>  
        <fpage>3</fpage>  
        <lpage>6</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.stcsig.org/usability/newsletter/index.html"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref72">
        <label>72</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Rosenberg</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Kottorp</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Winblad</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Nygård</surname>
            <given-names>L</given-names>
          </name>
        </person-group>
        <article-title>Perceived difficulty in everyday technology use among older adults with or without cognitive deficits</article-title>
        <source>Scand J Occup Ther</source>  
        <year>2009</year>  
        <volume>16</volume>  
        <issue>4</issue>  
        <fpage>216</fpage>  
        <lpage>26</lpage>  
        <pub-id pub-id-type="doi">10.3109/11038120802684299</pub-id>
        <pub-id pub-id-type="medline">19148847</pub-id>
        <pub-id pub-id-type="pii">907861236</pub-id></nlm-citation>
      </ref>
      <ref id="ref73">
        <label>73</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Heerink</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Kröse</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Evers</surname>
            <given-names>V</given-names>
          </name>
          <name name-style="western">
            <surname>Wielinga</surname>
            <given-names>B</given-names>
          </name>
        </person-group>
        <article-title>Assessing acceptance of assistive social agent technology by older adults: the Almere model</article-title>
        <source>Int J of Soc Robotics</source>  
        <year>2010</year>  
        <month>9</month>  
        <day>4</day>  
        <volume>2</volume>  
        <issue>4</issue>  
        <fpage>361</fpage>  
        <lpage>375</lpage>  
        <pub-id pub-id-type="doi">10.1007/s12369-010-0068-5</pub-id></nlm-citation>
      </ref>
      <ref id="ref74">
        <label>74</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Holthe</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Hagen</surname>
            <given-names>I</given-names>
          </name>
          <name name-style="western">
            <surname>Bjørneby</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Vollgate</surname>
            <given-names>Ø</given-names>
          </name>
        </person-group>
        <source>Forgetmenot</source>  
        <year>1998</year>  
        <access-date>2016-12-27</access-date>
        <publisher-name>Norwegian Centre for Dementia Research</publisher-name>
        <comment>Evaluation of an electronic calendar as helping aid for persons suffering from memory problems or cognitive impairment 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.forgetmenot.no/english/rapport-kalender.pdf">http://www.forgetmenot.no/english/rapport-kalender.pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHohS2r1"/></comment> </nlm-citation>
      </ref>
      <ref id="ref75">
        <label>75</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Lekeu</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Wojtasik</surname>
            <given-names>V</given-names>
          </name>
          <name name-style="western">
            <surname>Van der Linden</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Salmon</surname>
            <given-names>E</given-names>
          </name>
        </person-group>
        <article-title>Training early Alzheimer patients to use a mobile phone</article-title>
        <source>Acta Neurol Belg</source>  
        <year>2002</year>  
        <month>09</month>  
        <volume>102</volume>  
        <issue>3</issue>  
        <fpage>114</fpage>  
        <lpage>21</lpage>  
        <pub-id pub-id-type="medline">12400249</pub-id></nlm-citation>
      </ref>
      <ref id="ref76">
        <label>76</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Oriani</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Moniz-Cook</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Binetti</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Zanieri</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Frisoni</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Geroldi</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>De Vreese</surname>
            <given-names>LP</given-names>
          </name>
          <name name-style="western">
            <surname>Zanetti</surname>
            <given-names>O</given-names>
          </name>
        </person-group>
        <article-title>An electronic memory aid to support prospective memory in patients in the early stages of Alzheimer's disease: a pilot study</article-title>
        <source>Aging Ment Health</source>  
        <year>2003</year>  
        <month>01</month>  
        <volume>7</volume>  
        <issue>1</issue>  
        <fpage>22</fpage>  
        <lpage>7</lpage>  
        <pub-id pub-id-type="doi">10.1080/1360786021000045863</pub-id>
        <pub-id pub-id-type="medline">12554311</pub-id>
        <pub-id pub-id-type="pii">N5TY0048AXWJGV0U</pub-id></nlm-citation>
      </ref>
      <ref id="ref77">
        <label>77</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Cahill</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Begley</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Faulkner</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Hagen</surname>
            <given-names>I</given-names>
          </name>
        </person-group>
        <article-title>“It gives me a sense of independence” - Findings from Ireland on the use and usefulness of assistive technology for people with dementia</article-title>
        <source>Technol Disabil</source>  
        <year>2007</year>  
        <volume>19</volume>  
        <fpage>133</fpage>  
        <lpage>42</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://hdl.handle.net/2262/49836"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref78">
        <label>78</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Mihailidis</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Barbenel</surname>
            <given-names>JC</given-names>
          </name>
          <name name-style="western">
            <surname>Fernie</surname>
            <given-names>G</given-names>
          </name>
        </person-group>
        <article-title>The efficacy of an intelligent cognitive orthosis to facilitate handwashing by persons with moderate to severe dementia</article-title>
        <source>Neuropsychol Rehabil</source>  
        <year>2004</year>  
        <month>03</month>  
        <volume>14</volume>  
        <issue>1-2</issue>  
        <fpage>135</fpage>  
        <lpage>171</lpage>  
        <pub-id pub-id-type="doi">10.1080/09602010343000156</pub-id></nlm-citation>
      </ref>
      <ref id="ref79">
        <label>79</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Mihailidis</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Boger</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Craig</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Hoey</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>The COACH prompting system to assist older adults with dementia through handwashing: an efficacy study</article-title>
        <source>BMC Geriatr</source>  
        <year>2008</year>  
        <month>11</month>  
        <day>07</day>  
        <volume>8</volume>  
        <fpage>28</fpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://bmcgeriatr.biomedcentral.com/articles/10.1186/1471-2318-8-28"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1186/1471-2318-8-28</pub-id>
        <pub-id pub-id-type="medline">18992135</pub-id>
        <pub-id pub-id-type="pii">1471-2318-8-28</pub-id>
        <pub-id pub-id-type="pmcid">PMC2588599</pub-id></nlm-citation>
      </ref>
      <ref id="ref80">
        <label>80</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Bewernitz</surname>
            <given-names>MW</given-names>
          </name>
          <name name-style="western">
            <surname>Mann</surname>
            <given-names>W</given-names>
          </name>
          <name name-style="western">
            <surname>Dasler</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Belchior</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Feasibility of machine-based prompting to assist persons with dementia</article-title>
        <source>Assist Technol</source>  
        <year>2009</year>  
        <volume>21</volume>  
        <issue>4</issue>  
        <fpage>196</fpage>  
        <lpage>207</lpage>  
        <pub-id pub-id-type="doi">10.1080/10400430903246050</pub-id>
        <pub-id pub-id-type="medline">20066886</pub-id></nlm-citation>
      </ref>
      <ref id="ref81">
        <label>81</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Lancioni</surname>
            <given-names>GE</given-names>
          </name>
          <name name-style="western">
            <surname>Perilli</surname>
            <given-names>V</given-names>
          </name>
          <name name-style="western">
            <surname>Singh</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>O'Reilly</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Sigafoos</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Bosco</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>De Caro</surname>
            <given-names>MF</given-names>
          </name>
          <name name-style="western">
            <surname>Cassano</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Pinto</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Minervini</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Persons with mild or moderate Alzheimer's disease use a basic orientation technology to travel to different rooms within a day center</article-title>
        <source>Res Dev Disabil</source>  
        <year>2011</year>  
        <volume>32</volume>  
        <issue>5</issue>  
        <fpage>1895</fpage>  
        <lpage>901</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.ridd.2011.03.020</pub-id>
        <pub-id pub-id-type="medline">21501948</pub-id>
        <pub-id pub-id-type="pii">S0891-4222(11)00139-9</pub-id></nlm-citation>
      </ref>
      <ref id="ref82">
        <label>82</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Lancioni</surname>
            <given-names>GE</given-names>
          </name>
          <name name-style="western">
            <surname>Singh</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>O'Reilly</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Sigafoos</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Renna</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Ventrella</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Pinto</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Minervini</surname>
            <given-names>MG</given-names>
          </name>
          <name name-style="western">
            <surname>Oliva</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Groeneweg</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Supporting daily activities and indoor travel of persons with moderate Alzheimer's disease through standard technology resources</article-title>
        <source>Res Dev Disabil</source>  
        <year>2013</year>  
        <month>08</month>  
        <volume>34</volume>  
        <issue>8</issue>  
        <fpage>2351</fpage>  
        <lpage>9</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.ridd.2013.04.020</pub-id>
        <pub-id pub-id-type="medline">23711628</pub-id>
        <pub-id pub-id-type="pii">S0891-4222(13)00182-0</pub-id></nlm-citation>
      </ref>
      <ref id="ref83">
        <label>83</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Lancioni</surname>
            <given-names>GE</given-names>
          </name>
          <name name-style="western">
            <surname>Perilli</surname>
            <given-names>V</given-names>
          </name>
          <name name-style="western">
            <surname>O'Reilly</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Singh</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Sigafoos</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Bosco</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Caffò</surname>
            <given-names>AO</given-names>
          </name>
          <name name-style="western">
            <surname>Picucci</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Cassano</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Groeneweg</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Technology-based orientation programs to support indoor travel by persons with moderate Alzheimer's disease: impact assessment and social validation</article-title>
        <source>Res Dev Disabil</source>  
        <year>2013</year>  
        <month>01</month>  
        <volume>34</volume>  
        <issue>1</issue>  
        <fpage>286</fpage>  
        <lpage>93</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.ridd.2012.08.016</pub-id>
        <pub-id pub-id-type="medline">22982468</pub-id>
        <pub-id pub-id-type="pii">S0891-4222(12)00222-3</pub-id></nlm-citation>
      </ref>
      <ref id="ref84">
        <label>84</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Yasuda</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Beckman</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Yoneda</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Yoneda</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Iwamoto</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Nakamura</surname>
            <given-names>T</given-names>
          </name>
        </person-group>
        <article-title>Successful guidance by automatic output of music and verbal messages for daily behavioural disturbances of three individuals with dementia</article-title>
        <source>Neuropsychol Rehabil</source>  
        <year>2006</year>  
        <month>02</month>  
        <volume>16</volume>  
        <issue>1</issue>  
        <fpage>66</fpage>  
        <lpage>82</lpage>  
        <pub-id pub-id-type="doi">10.1080/09602010443000191</pub-id>
        <pub-id pub-id-type="medline">16509519</pub-id></nlm-citation>
      </ref>
      <ref id="ref85">
        <label>85</label>
        <nlm-citation citation-type="web">
        <source>Cogknow</source>  
        <access-date>2016-10-16</access-date>
        <comment>Cogknow: Overview 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://cogknow.eu/">http://cogknow.eu/</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHlKMK8Y"/></comment> </nlm-citation>
      </ref>
      <ref id="ref86">
        <label>86</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Wilson</surname>
            <given-names>BA</given-names>
          </name>
          <name name-style="western">
            <surname>Emslie</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Quirk</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Evans</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Reducing everyday memory and planning problems by means of a paging system: a randomised control crossover study</article-title>
        <source>J Neurol Neurosurg Psychiatry</source>  
        <year>2001</year>  
        <month>04</month>  
        <volume>70</volume>  
        <issue>4</issue>  
        <fpage>477</fpage>  
        <lpage>82</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://jnnp.bmj.com/cgi/pmidlookup?view=long&#38;pmid=11254770"/>
        </comment>  
        <pub-id pub-id-type="medline">11254770</pub-id>
        <pub-id pub-id-type="pmcid">PMC1737307</pub-id></nlm-citation>
      </ref>
      <ref id="ref87">
        <label>87</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Altus</surname>
            <given-names>DE</given-names>
          </name>
          <name name-style="western">
            <surname>Mathews</surname>
            <given-names>RM</given-names>
          </name>
          <name name-style="western">
            <surname>Xaverius</surname>
            <given-names>PK</given-names>
          </name>
          <name name-style="western">
            <surname>Engelman</surname>
            <given-names>KK</given-names>
          </name>
          <name name-style="western">
            <surname>Nolan</surname>
            <given-names>BAD</given-names>
          </name>
        </person-group>
        <article-title>Evaluating an electronic monitoring system for people who wander</article-title>
        <source>Am J Alzheimers Dis Other Demen</source>  
        <year>2000</year>  
        <month>03</month>  
        <day>01</day>  
        <volume>15</volume>  
        <issue>2</issue>  
        <fpage>121</fpage>  
        <lpage>25</lpage>  
        <pub-id pub-id-type="doi">10.1177/153331750001500201</pub-id></nlm-citation>
      </ref>
      <ref id="ref88">
        <label>88</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Miskelly</surname>
            <given-names>F</given-names>
          </name>
        </person-group>
        <article-title>A novel system of electronic tagging in patients with dementia and wandering</article-title>
        <source>Age Ageing</source>  
        <year>2004</year>  
        <month>05</month>  
        <volume>33</volume>  
        <issue>3</issue>  
        <fpage>304</fpage>  
        <lpage>6</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://ageing.oxfordjournals.org/cgi/pmidlookup?view=long&#38;pmid=15082438"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1093/ageing/afh084</pub-id>
        <pub-id pub-id-type="medline">15082438</pub-id>
        <pub-id pub-id-type="pii">33/3/304</pub-id></nlm-citation>
      </ref>
      <ref id="ref89">
        <label>89</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>McShane</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Gedling</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Kenward</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Kenward</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Hope</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Jacoby</surname>
            <given-names>R</given-names>
          </name>
        </person-group>
        <article-title>The feasibility of electronic tracking devices in dementia: a telephone survey and case series</article-title>
        <source>Int J Geriatr Psychiatry</source>  
        <year>1998</year>  
        <month>08</month>  
        <volume>13</volume>  
        <issue>8</issue>  
        <fpage>556</fpage>  
        <lpage>63</lpage>  
        <pub-id pub-id-type="medline">9733337</pub-id>
        <pub-id pub-id-type="pii">10.1002/(SICI)1099-1166(199808)13:8&#60;556::AID-GPS834&#62;3.0.CO;2-6</pub-id></nlm-citation>
      </ref>
      <ref id="ref90">
        <label>90</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Ikarashi</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Magara</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Nonaka</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Ohno</surname>
            <given-names>H</given-names>
          </name>
        </person-group>
        <article-title>The searching system for wandering demented aged person using GPS</article-title>
        <source>IEEJ Trans IA</source>  
        <year>2002</year>  
        <volume>122</volume>  
        <issue>6</issue>  
        <fpage>609</fpage>  
        <lpage>16</lpage>  
        <pub-id pub-id-type="doi">10.1541/ieejias.122.609</pub-id></nlm-citation>
      </ref>
      <ref id="ref91">
        <label>91</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Tárraga</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Boada</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Modinos</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Espinosa</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Diego</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Morera</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Guitart</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Balcells</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>López</surname>
            <given-names>OL</given-names>
          </name>
          <name name-style="western">
            <surname>Becker</surname>
            <given-names>JT</given-names>
          </name>
        </person-group>
        <article-title>A randomised pilot study to assess the efficacy of an interactive, multimedia tool of cognitive stimulation in Alzheimer's disease</article-title>
        <source>J Neurol Neurosurg Psychiatry</source>  
        <year>2006</year>  
        <month>10</month>  
        <volume>77</volume>  
        <issue>10</issue>  
        <fpage>1116</fpage>  
        <lpage>21</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/16820420"/>
        </comment>  
        <pub-id pub-id-type="doi">10.1136/jnnp.2005.086074</pub-id>
        <pub-id pub-id-type="medline">16820420</pub-id>
        <pub-id pub-id-type="pii">jnnp.2005.086074</pub-id>
        <pub-id pub-id-type="pmcid">PMC2077529</pub-id></nlm-citation>
      </ref>
      <ref id="ref92">
        <label>92</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Schreiber</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Potential of an interactive computer-based training in the rehabilitation of Dementia: an initial study</article-title>
        <source>Neuropsychol Rehabil</source>  
        <year>1999</year>  
        <month>04</month>  
        <volume>9</volume>  
        <issue>2</issue>  
        <fpage>155</fpage>  
        <lpage>167</lpage>  
        <pub-id pub-id-type="doi">10.1080/713755596</pub-id></nlm-citation>
      </ref>
      <ref id="ref93">
        <label>93</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Mate-Kole</surname>
            <given-names>CC</given-names>
          </name>
          <name name-style="western">
            <surname>Fellows</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Said</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>McDougal</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Catayong</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Dang</surname>
            <given-names>V</given-names>
          </name>
          <name name-style="western">
            <surname>Gianesini</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Use of computer assisted and interactive cognitive training programmes with moderate to severely demented individuals: a preliminary study</article-title>
        <source>Aging Ment Health</source>  
        <year>2007</year>  
        <month>09</month>  
        <volume>11</volume>  
        <issue>5</issue>  
        <fpage>485</fpage>  
        <lpage>95</lpage>  
        <pub-id pub-id-type="doi">10.1080/13607860701368422</pub-id>
        <pub-id pub-id-type="medline">17882586</pub-id>
        <pub-id pub-id-type="pii">782165437</pub-id></nlm-citation>
      </ref>
      <ref id="ref94">
        <label>94</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Burdea</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Rabin</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Rethage</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Damiani</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Hundal</surname>
            <given-names>JS</given-names>
          </name>
          <name name-style="western">
            <surname>Fitzpatrick</surname>
            <given-names>C</given-names>
          </name>
        </person-group>
        <source>Brightcloudint</source>  
        <year>2013</year>  
        <access-date>2016-10-11</access-date>
        <comment>BrightArm™ Therapy for Patients with Advanced Dementia 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://brightcloudint.com/wp-content/uploads/BrightArm%E2%84%A2-Therapy-for-Patients-with-Advanced-Dementia.pdf">http://brightcloudint.com/wp-content/uploads/BrightArm%E2%84%A2-Therapy-for-Patients-with-Advanced-Dementia.pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lBgdC7KN"/></comment> </nlm-citation>
      </ref>
      <ref id="ref95">
        <label>95</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Leuty</surname>
            <given-names>V</given-names>
          </name>
          <name name-style="western">
            <surname>Boger</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Young</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Hoey</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Mihailidis</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>Engaging older adults with dementia in creative occupations using artificially intelligent assistive technology</article-title>
        <source>Assist Technol</source>  
        <year>2013</year>  
        <volume>25</volume>  
        <issue>2</issue>  
        <fpage>72</fpage>  
        <lpage>9</lpage>  
        <pub-id pub-id-type="doi">10.1080/10400435.2012.715113</pub-id>
        <pub-id pub-id-type="medline">23923689</pub-id></nlm-citation>
      </ref>
      <ref id="ref96">
        <label>96</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Riley</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Alm</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Newell</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>An interactive tool to promote musical creativity in people with dementia</article-title>
        <source>Comput Human Behav</source>  
        <year>2009</year>  
        <month>5</month>  
        <volume>25</volume>  
        <issue>3</issue>  
        <fpage>599</fpage>  
        <lpage>608</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.chb.2008.08.014</pub-id></nlm-citation>
      </ref>
      <ref id="ref97">
        <label>97</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Wada</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Shibata</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Musha</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Kimura</surname>
            <given-names>S</given-names>
          </name>
        </person-group>
        <article-title>Robot therapy for elders affected by dementia</article-title>
        <source>IEEE Eng Med Biol Mag</source>  
        <year>2008</year>  
        <month>07</month>  
        <volume>27</volume>  
        <issue>4</issue>  
        <fpage>53</fpage>  
        <lpage>60</lpage>  
        <pub-id pub-id-type="doi">10.1109/MEMB.2008.919496</pub-id></nlm-citation>
      </ref>
      <ref id="ref98">
        <label>98</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Hanson</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Magnusson</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Arvidsson</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Claesson</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Keady</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Nolan</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Working together with persons with early stage dementia and their family members to design a user-friendly technology-based support service</article-title>
        <source>Dementia</source>  
        <year>2007</year>  
        <month>08</month>  
        <day>01</day>  
        <volume>6</volume>  
        <issue>3</issue>  
        <fpage>411</fpage>  
        <lpage>34</lpage>  
        <pub-id pub-id-type="doi">10.1177/1471301207081572</pub-id></nlm-citation>
      </ref>
      <ref id="ref99">
        <label>99</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Gilliard</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Editorial</article-title>
        <source>Dementia</source>  
        <year>2004</year>  
        <month>10</month>  
        <day>01</day>  
        <volume>3</volume>  
        <issue>3</issue>  
        <fpage>259</fpage>  
        <lpage>61</lpage>  
        <pub-id pub-id-type="doi">10.1177/1471301204045159</pub-id></nlm-citation>
      </ref>
      <ref id="ref100">
        <label>100</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Topo</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Mäki</surname>
            <given-names>O</given-names>
          </name>
          <name name-style="western">
            <surname>Saarikalle</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Clarke</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Begley</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Cahill</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Arenlind</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Holthe</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Morbey</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Hayes</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Gilliard</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Assessment of a music-Based multimedia program for People with Dementia</article-title>
        <source>Dementia</source>  
        <year>2004</year>  
        <month>10</month>  
        <day>01</day>  
        <volume>3</volume>  
        <issue>3</issue>  
        <fpage>331</fpage>  
        <lpage>50</lpage>  
        <pub-id pub-id-type="doi">10.1177/1471301204045164</pub-id></nlm-citation>
      </ref>
      <ref id="ref101">
        <label>101</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Kuwahara</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Yasuda</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Tetsutani</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Morimoto</surname>
            <given-names>K</given-names>
          </name>
        </person-group>
        <article-title>Remote assistance for people with dementia at home using reminiscence systems and a schedule prompter</article-title>
        <source>Int J Comp Healthcare</source>  
        <year>2010</year>  
        <volume>1</volume>  
        <issue>2</issue>  
        <fpage>126</fpage>  
        <pub-id pub-id-type="doi">10.1504/IJCIH.2010.037458</pub-id></nlm-citation>
      </ref>
      <ref id="ref102">
        <label>102</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Alm</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Astell</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Gowans</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Dye</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Ellis</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Vaughan</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Riley</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Engaging multimedia leisure for people with dementia</article-title>
        <source>Gerontechnology</source>  
        <year>2009</year>  
        <volume>8</volume>  
        <issue>4</issue>  
        <fpage>236</fpage>  
        <lpage>46</lpage>  
        <pub-id pub-id-type="doi">10.4017/gt.2009.08.04.006.00</pub-id></nlm-citation>
      </ref>
      <ref id="ref103">
        <label>103</label>
        <nlm-citation citation-type="confproc">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Alm</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Dye</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Gowans</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Campbell</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Astell</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Ellis</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Designing an interface usable by people with dementia</article-title>
        <source>CUU '03 Proceedings of the 2003 conference on Universal usability</source>  
        <year>2003</year>  
        <conf-name>Conference on Universal Usability</conf-name>
        <conf-date>November 10-11, 2003</conf-date>
        <conf-loc>Vancouver, British Columbia, Canada</conf-loc>
        <publisher-loc>New York, NY, USA</publisher-loc>
        <publisher-name>ACM</publisher-name>
        <fpage>156</fpage>  
        <lpage>7</lpage>  
        <pub-id pub-id-type="doi">10.1145/957205.957237</pub-id></nlm-citation>
      </ref>
      <ref id="ref104">
        <label>104</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Fleischmann</surname>
            <given-names>VS</given-names>
          </name>
          <name name-style="western">
            <surname>Tractinsky</surname>
            <given-names>N</given-names>
          </name>
        </person-group>
        <article-title>Development and evaluation of a personalised multimedia system for reminiscence therapy in Alzheimer's patients</article-title>
        <source>Int J Soc Hum Computing</source>  
        <year>2008</year>  
        <volume>1</volume>  
        <issue>1</issue>  
        <fpage>81</fpage>  
        <pub-id pub-id-type="doi">10.1504/IJSHC.2008.020482</pub-id></nlm-citation>
      </ref>
      <ref id="ref105">
        <label>105</label>
        <nlm-citation citation-type="confproc">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Astell</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Ellis</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Bernardi</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Alm</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Dye</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Gowans</surname>
            <given-names>G</given-names>
          </name>
        </person-group>
        <article-title>Developing technology to support the relationship between people with dementia and caregivers</article-title>
        <source>22nd Conference of Alzheimer's Disease International</source>  
        <year>2007</year>  
        <conf-name>Proceedings of the 22nd Conference of Alzheimer's Disease International</conf-name>
        <conf-date>2007</conf-date>
        <conf-loc>Berlin, Germany</conf-loc>
        <fpage>30</fpage>  
        <lpage>3</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://www.researchgate.net/profile/Arlene_Astell/publication/265192971_Developing_Technology_to_Support_the_Relationship_between_People_with_Dementia_and_Caregivers/links/548207a30cf2f5dd63a8961a.pdf"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref106">
        <label>106</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Astell</surname>
            <given-names>AJ</given-names>
          </name>
          <name name-style="western">
            <surname>Ellis</surname>
            <given-names>MP</given-names>
          </name>
          <name name-style="western">
            <surname>Bernardi</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Alm</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Dye</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Gowans</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Campbell</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Using a touch screen computer to support relationships between people with dementia and caregivers</article-title>
        <source>Interact Comput</source>  
        <year>2010</year>  
        <month>7</month>  
        <volume>22</volume>  
        <issue>4</issue>  
        <fpage>267</fpage>  
        <lpage>75</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.intcom.2010.03.003</pub-id></nlm-citation>
      </ref>
      <ref id="ref107">
        <label>107</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Olsen</surname>
            <given-names>RV</given-names>
          </name>
          <name name-style="western">
            <surname>Hutchings</surname>
            <given-names>BL</given-names>
          </name>
          <name name-style="western">
            <surname>Ehrenkrantz</surname>
            <given-names>E</given-names>
          </name>
        </person-group>
        <article-title>“Media Memory Lane” interventions in an Alzheimer's day care center</article-title>
        <source>Am J Alzheimers Dis Other Demen</source>  
        <year>2000</year>  
        <month>05</month>  
        <day>01</day>  
        <volume>15</volume>  
        <issue>3</issue>  
        <fpage>163</fpage>  
        <lpage>75</lpage>  
        <pub-id pub-id-type="doi">10.1177/153331750001500307</pub-id></nlm-citation>
      </ref>
      <ref id="ref108">
        <label>108</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Topo</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Jylhä</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Laine</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Can the telephone-using abilities of people with dementia be promoted? An evaluation of a simple-to-use telephone</article-title>
        <source>Technol Disabil</source>  
        <year>2002</year>  
        <month>2</month>  
        <volume>14</volume>  
        <issue>1</issue>  
        <fpage>3</fpage>  
        <lpage>13</lpage> </nlm-citation>
      </ref>
      <ref id="ref109">
        <label>109</label>
        <nlm-citation citation-type="book">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Kort</surname>
            <given-names>S</given-names>
          </name>
        </person-group>
        <article-title>Mobile Coaching. A pilot study into the user-friendliness and effects of Mobile Coaching on the wellbeing of people with dementia and their informal caregivers</article-title>
        <source>aculty of Psychology, Vrije Universteit, Amsterdam; 2005.</source> </nlm-citation>
      </ref>
      <ref id="ref110">
        <label>110</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Sävenstedt</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Brulin</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Sandman</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Family members' narrated experiences of communicating via video-phone with patients with dementia staying at a nursing home</article-title>
        <source>J Telemed Telecare</source>  
        <year>2003</year>  
        <volume>9</volume>  
        <issue>4</issue>  
        <fpage>216</fpage>  
        <lpage>20</lpage>  
        <pub-id pub-id-type="doi">10.1258/135763303322225544</pub-id>
        <pub-id pub-id-type="medline">12952692</pub-id></nlm-citation>
      </ref>
      <ref id="ref111">
        <label>111</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Chan</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Campo</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Estève</surname>
            <given-names>D</given-names>
          </name>
        </person-group>
        <article-title>Assessment of activity of elderly people using a home monitoring system</article-title>
        <source>Int J Rehabil Res</source>  
        <year>2005</year>  
        <month>03</month>  
        <volume>28</volume>  
        <issue>1</issue>  
        <fpage>69</fpage>  
        <lpage>76</lpage>  
        <pub-id pub-id-type="medline">15729100</pub-id>
        <pub-id pub-id-type="pii">00004356-200503000-00010</pub-id></nlm-citation>
      </ref>
      <ref id="ref112">
        <label>112</label>
        <nlm-citation citation-type="web">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Curry</surname>
            <given-names>RG</given-names>
          </name>
          <name name-style="western">
            <surname>Tinoco</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Wardle</surname>
            <given-names>D</given-names>
          </name>
        </person-group>
        <source>Citeseerx.ist</source>  
        <year>2002</year>  
        <access-date>2016-12-27</access-date>
        <publisher-loc>London</publisher-loc>
        <publisher-name>Department of Health</publisher-name>
        <comment>The use of information and communication technology (ICT) to support independent living for older and disabled people 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.199.17&#38;rep=rep1&#38;type=pdf">http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.199.17&#38;rep=rep1&#38;type=pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6n75i1sSu"/></comment> </nlm-citation>
      </ref>
      <ref id="ref113">
        <label>113</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Rowe</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Lane</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Phipps</surname>
            <given-names>C</given-names>
          </name>
        </person-group>
        <article-title>CareWatch: a home monitoring system for use in homes of persons with cognitive impairment</article-title>
        <source>Top Geriatr Rehabil</source>  
        <year>2007</year>  
        <month>01</month>  
        <day>01</day>  
        <volume>23</volume>  
        <issue>1</issue>  
        <fpage>3</fpage>  
        <lpage>8</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://europepmc.org/abstract/MED/20454554"/>
        </comment>  
        <pub-id pub-id-type="medline">20454554</pub-id>
        <pub-id pub-id-type="pmcid">PMC2865687</pub-id></nlm-citation>
      </ref>
      <ref id="ref114">
        <label>114</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Barlow</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Bayer</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Castleton</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Curry</surname>
            <given-names>R</given-names>
          </name>
        </person-group>
        <article-title>Meeting government objectives for telecare in moving from local implementation to mainstream services</article-title>
        <source>J Telemed Telecare</source>  
        <year>2005</year>  
        <volume>11</volume>  
        <issue>Suppl 1</issue>  
        <fpage>49</fpage>  
        <lpage>51</lpage>  
        <pub-id pub-id-type="medline">16124135</pub-id></nlm-citation>
      </ref>
      <ref id="ref115">
        <label>115</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Woolham</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Frisby</surname>
            <given-names>B</given-names>
          </name>
        </person-group>
        <article-title>How technology can help people feel safe at home</article-title>
        <source>J Dem Care</source>  
        <year>2002</year>  
        <volume>10</volume>  
        <issue>2</issue>  
        <fpage>27</fpage>  
        <lpage>8</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.careinfo.org/2002/03/"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref116">
        <label>116</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Moriarty</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Baruch</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Downs</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Baldwin</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Bruce</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Richardson</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Kitchen</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Livingston</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Freeman-Asthill</surname>
            <given-names>L</given-names>
          </name>
        </person-group>
        <article-title>Innovative practice</article-title>
        <source>Dementia</source>  
        <year>2004</year>  
        <month>10</month>  
        <day>01</day>  
        <volume>3</volume>  
        <issue>3</issue>  
        <fpage>371</fpage>  
        <lpage>92</lpage>  
        <pub-id pub-id-type="doi">10.1177/1471301204045192</pub-id></nlm-citation>
      </ref>
      <ref id="ref117">
        <label>117</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Loh</surname>
            <given-names>PK</given-names>
          </name>
          <name name-style="western">
            <surname>Donaldson</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Flicker</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Maher</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Goldswain</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Development of a telemedicine protocol for the diagnosis of Alzheimer's disease</article-title>
        <source>J Telemed Telecare</source>  
        <year>2007</year>  
        <volume>13</volume>  
        <issue>2</issue>  
        <fpage>90</fpage>  
        <lpage>4</lpage>  
        <pub-id pub-id-type="doi">10.1258/135763307780096159</pub-id>
        <pub-id pub-id-type="medline">17359573</pub-id></nlm-citation>
      </ref>
      <ref id="ref118">
        <label>118</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Poon</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Hui</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Dai</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Kwok</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Woo</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Cognitive intervention for community-dwelling older persons with memory problems: telemedicine versus face-to-face treatment</article-title>
        <source>Int J Geriatr Psychiatry</source>  
        <year>2005</year>  
        <month>03</month>  
        <volume>20</volume>  
        <issue>3</issue>  
        <fpage>285</fpage>  
        <lpage>6</lpage>  
        <pub-id pub-id-type="doi">10.1002/gps.1282</pub-id>
        <pub-id pub-id-type="medline">15717335</pub-id></nlm-citation>
      </ref>
      <ref id="ref119">
        <label>119</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Cullum</surname>
            <given-names>CM</given-names>
          </name>
          <name name-style="western">
            <surname>Weiner</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Gehrmann</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Hynan</surname>
            <given-names>L</given-names>
          </name>
        </person-group>
        <article-title>Feasibility of telecognitive assessment in dementia</article-title>
        <source>Assessment</source>  
        <year>2006</year>  
        <month>12</month>  
        <volume>13</volume>  
        <issue>4</issue>  
        <fpage>385</fpage>  
        <lpage>90</lpage>  
        <pub-id pub-id-type="doi">10.1177/1073191106289065</pub-id>
        <pub-id pub-id-type="medline">17050908</pub-id>
        <pub-id pub-id-type="pii">13/4/385</pub-id></nlm-citation>
      </ref>
      <ref id="ref120">
        <label>120</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Lee</surname>
            <given-names>JH</given-names>
          </name>
          <name name-style="western">
            <surname>Kim</surname>
            <given-names>JH</given-names>
          </name>
          <name name-style="western">
            <surname>Jhoo</surname>
            <given-names>JH</given-names>
          </name>
          <name name-style="western">
            <surname>Lee</surname>
            <given-names>KU</given-names>
          </name>
          <name name-style="western">
            <surname>Kim</surname>
            <given-names>KW</given-names>
          </name>
          <name name-style="western">
            <surname>Lee</surname>
            <given-names>DY</given-names>
          </name>
          <name name-style="western">
            <surname>Woo</surname>
            <given-names>JI</given-names>
          </name>
        </person-group>
        <article-title>A telemedicine system as a care modality for dementia patients in Korea</article-title>
        <source>Alzheimer Dis Assoc Disord</source>  
        <year>2000</year>  
        <volume>14</volume>  
        <issue>2</issue>  
        <fpage>94</fpage>  
        <lpage>101</lpage>  
        <pub-id pub-id-type="medline">10850748</pub-id></nlm-citation>
      </ref>
      <ref id="ref121">
        <label>121</label>
        <nlm-citation citation-type="web">
        <source>Ambient Assisted Living-Association</source>  
        <year>2014</year>  
        <access-date>2016-10-15</access-date>
        <comment>Study concerning a market observatory in the ambient assisted living field 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.aal-europe.eu/wp-content/uploads/2016/03/Final-report-SA-Market-observatory.pdf">http://www.aal-europe.eu/wp-content/uploads/2016/03/Final-report-SA-Market-observatory.pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHmDGRf5"/></comment> </nlm-citation>
      </ref>
      <ref id="ref122">
        <label>122</label>
        <nlm-citation citation-type="web">
        <source>National Library of Medicine (US)</source>  
        <access-date>2016-10-16</access-date>
        <comment>Health Services/Technology Assessment Texts (HSTAT) 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://www.ncbi.nlm.nih.gov/books/NBK16710/">https://www.ncbi.nlm.nih.gov/books/NBK16710/</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHmIQfQH"/></comment> </nlm-citation>
      </ref>
      <ref id="ref123">
        <label>123</label>
        <nlm-citation citation-type="web">
        <source>University of York</source>  
        <access-date>2016-10-15</access-date>
        <comment>Centre for Reviews and Dissemination 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.york.ac.uk/crd/">http://www.york.ac.uk/crd/</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHmL25K1"/></comment> </nlm-citation>
      </ref>
      <ref id="ref124">
        <label>124</label>
        <nlm-citation citation-type="web">
        <source>German Institute of Medical Documentation and Information</source>  
        <access-date>2016-10-16</access-date>
        <comment>DIMDI Medical Knowledge 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.dimdi.de/static/en/hta/index.htm">http://www.dimdi.de/static/en/hta/index.htm</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHmqXEH1"/></comment> </nlm-citation>
      </ref>
      <ref id="ref125">
        <label>125</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Jimison</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Gorman</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Woods</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Nygren</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Walker</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Norris</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Hersh</surname>
            <given-names>W</given-names>
          </name>
        </person-group>
        <article-title>Barriers and drivers of health information technology use for the elderly, chronically ill, and underserved</article-title>
        <source>Evid Rep Technol Assess (Full Rep)</source>  
        <year>2008</year>  
        <month>11</month>  
        <issue>175</issue>  
        <fpage>1</fpage>  
        <lpage>1422</lpage>  
        <pub-id pub-id-type="medline">19408968</pub-id>
        <pub-id pub-id-type="pmcid">PMC4781044</pub-id></nlm-citation>
      </ref>
      <ref id="ref126">
        <label>126</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Finkelstein</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Knight</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Marinopoulos</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Gibbons</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Berger</surname>
            <given-names>Z</given-names>
          </name>
          <name name-style="western">
            <surname>Aboumatar</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Wilson</surname>
            <given-names>RF</given-names>
          </name>
          <name name-style="western">
            <surname>Lau</surname>
            <given-names>BD</given-names>
          </name>
          <name name-style="western">
            <surname>Sharma</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Bass</surname>
            <given-names>E</given-names>
          </name>
        </person-group>
        <article-title>Enabling patient-centered care through health information technology</article-title>
        <source>Evid Rep Technol Assess (Full Rep)</source>  
        <year>2012</year>  
        <month>06</month>  
        <issue>206</issue>  
        <fpage>1</fpage>  
        <lpage>1531</lpage>  
        <pub-id pub-id-type="medline">24422882</pub-id>
        <pub-id pub-id-type="pmcid">PMC4781073</pub-id></nlm-citation>
      </ref>
      <ref id="ref127">
        <label>127</label>
        <nlm-citation citation-type="web">
        <source>NHS</source>  
        <comment>The ATTILA Trial: Assistive Technology and Telecare to maintain Independent Living At home for people with dementia 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.nets.nihr.ac.uk/__data/assets/pdf_file/0008/81665/PRO-10-50-02.pdf">http://www.nets.nihr.ac.uk/__data/assets/pdf_file/0008/81665/PRO-10-50-02.pdf</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHmuwmbN"/></comment> </nlm-citation>
      </ref>
      <ref id="ref128">
        <label>128</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Van der Roest</surname>
            <given-names>HG</given-names>
          </name>
          <name name-style="western">
            <surname>Wenborn</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Dröes</surname>
            <given-names>RM</given-names>
          </name>
          <name name-style="western">
            <surname>Orrell</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Assistive technology for memory support in dementia</article-title>
        <source>Cochrane Database Syst Rev</source>  
        <year>2012</year>  
        <month>02</month>  
        <issue>2</issue>  
        <pub-id pub-id-type="doi">10.1002/14651858.CD009627</pub-id></nlm-citation>
      </ref>
      <ref id="ref129">
        <label>129</label>
        <nlm-citation citation-type="web">
        <source>JPND Research</source>  
        <year>2014</year>  
        <access-date>2016-10-15</access-date>
        <comment>Assisted Living Technologies 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.neurodegenerationresearch.eu/initiatives/jpnd-alignment-actions/assisted-living-technologies/">http://www.neurodegenerationresearch.eu/initiatives/jpnd-alignment-actions/assisted-living-technologies/</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHmyiEVn"/></comment> </nlm-citation>
      </ref>
      <ref id="ref130">
        <label>130</label>
        <nlm-citation citation-type="web">
        <source>Trent Dementia Services Development Centre</source>  
        <access-date>2016-10-15</access-date>
        <comment>AT Dementia: Information on assistive technology for people with dementia 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://www.atdementia.org.uk/">https://www.atdementia.org.uk/</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHn8Nqq0"/></comment> </nlm-citation>
      </ref>
      <ref id="ref131">
        <label>131</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Cash</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Assistive technology and people with dementia</article-title>
        <source>Rev Clin Gerontol</source>  
        <year>1999</year>  
        <volume>13</volume>  
        <issue>4</issue>  
        <fpage>313</fpage>  
        <lpage>19</lpage>  
        <pub-id pub-id-type="doi">10.1017/S0959259804001169</pub-id></nlm-citation>
      </ref>
      <ref id="ref132">
        <label>132</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Kang</surname>
            <given-names>HG</given-names>
          </name>
          <name name-style="western">
            <surname>Mahoney</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Hoenig</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Hirth</surname>
            <given-names>V</given-names>
          </name>
          <name name-style="western">
            <surname>Bonato</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Hajjar</surname>
            <given-names>I</given-names>
          </name>
          <name name-style="western">
            <surname>Lipsitz</surname>
            <given-names>LA</given-names>
          </name>
          <collab>Center for Integration of Medicine and Innovative Technology Working Group on Advanced Approaches to Physiologic Monitoring for the Aged</collab>
        </person-group>
        <article-title>In situ monitoring of health in older adults: technologies and issues</article-title>
        <source>J Am Geriatr Soc</source>  
        <year>2010</year>  
        <month>08</month>  
        <volume>58</volume>  
        <issue>8</issue>  
        <fpage>1579</fpage>  
        <lpage>86</lpage>  
        <pub-id pub-id-type="doi">10.1111/j.1532-5415.2010.02959.x</pub-id>
        <pub-id pub-id-type="medline">20646105</pub-id>
        <pub-id pub-id-type="pii">JGS2959</pub-id></nlm-citation>
      </ref>
      <ref id="ref133">
        <label>133</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Landau</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Auslander</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Werner</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Shoval</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Heinik</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Families' and professional caregivers' views of using advanced technology to track people with dementia</article-title>
        <source>Qual Health Res</source>  
        <year>2010</year>  
        <month>03</month>  
        <volume>20</volume>  
        <issue>3</issue>  
        <fpage>409</fpage>  
        <lpage>19</lpage>  
        <pub-id pub-id-type="doi">10.1177/1049732309359171</pub-id>
        <pub-id pub-id-type="medline">20133506</pub-id>
        <pub-id pub-id-type="pii">20/3/409</pub-id></nlm-citation>
      </ref>
      <ref id="ref134">
        <label>134</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Landau</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Auslander</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Werner</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Shoval</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Heinik</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Who should make the decision on the use of GPS for people with dementia?</article-title>
        <source>Aging Ment Health</source>  
        <year>2011</year>  
        <month>01</month>  
        <volume>15</volume>  
        <issue>1</issue>  
        <fpage>78</fpage>  
        <lpage>84</lpage>  
        <pub-id pub-id-type="doi">10.1080/13607861003713166</pub-id>
        <pub-id pub-id-type="medline">20924823</pub-id>
        <pub-id pub-id-type="pii">927612720</pub-id></nlm-citation>
      </ref>
      <ref id="ref135">
        <label>135</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Landau</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Werner</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Auslander</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Shoval</surname>
            <given-names>N</given-names>
          </name>
          <name name-style="western">
            <surname>Heinik</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>What do cognitively intact older people think about the use of electronic tracking devices for people with dementia? A preliminary analysis</article-title>
        <source>Int Psychogeriatr</source>  
        <year>2010</year>  
        <month>12</month>  
        <volume>22</volume>  
        <issue>8</issue>  
        <fpage>1301</fpage>  
        <lpage>9</lpage>  
        <pub-id pub-id-type="doi">10.1017/S1041610210001316</pub-id>
        <pub-id pub-id-type="medline">20594387</pub-id>
        <pub-id pub-id-type="pii">S1041610210001316</pub-id></nlm-citation>
      </ref>
      <ref id="ref136">
        <label>136</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Landau</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Werner</surname>
            <given-names>S</given-names>
          </name>
        </person-group>
        <article-title>Ethical aspects of using GPS for tracking people with dementia: recommendations for practice</article-title>
        <source>Int Psychogeriatr</source>  
        <year>2012</year>  
        <month>03</month>  
        <volume>24</volume>  
        <issue>3</issue>  
        <fpage>358</fpage>  
        <lpage>66</lpage>  
        <pub-id pub-id-type="doi">10.1017/S1041610211001888</pub-id>
        <pub-id pub-id-type="medline">22014284</pub-id>
        <pub-id pub-id-type="pii">S1041610211001888</pub-id></nlm-citation>
      </ref>
      <ref id="ref137">
        <label>137</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Lindqvist</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Nygård</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Borell</surname>
            <given-names>L</given-names>
          </name>
        </person-group>
        <article-title>Significant junctures on the way towards becoming a user of assistive technology in Alzheimer's disease</article-title>
        <source>Scand J Occup Ther</source>  
        <year>2013</year>  
        <month>09</month>  
        <volume>20</volume>  
        <issue>5</issue>  
        <fpage>386</fpage>  
        <lpage>96</lpage>  
        <pub-id pub-id-type="doi">10.3109/11038128.2013.766761</pub-id>
        <pub-id pub-id-type="medline">23394183</pub-id></nlm-citation>
      </ref>
      <ref id="ref138">
        <label>138</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Mahoney</surname>
            <given-names>DF</given-names>
          </name>
          <name name-style="western">
            <surname>Purtilo</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Webbe</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Alwan</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Bharucha</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Adlam</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Jimison</surname>
            <given-names>HB</given-names>
          </name>
          <name name-style="western">
            <surname>Turner</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Becker</surname>
            <given-names>SA</given-names>
          </name>
          <collab>Working Group on Technology of the Alzheimer's Association</collab>
        </person-group>
        <article-title>In-home monitoring of persons with dementia: ethical guidelines for technology research and development</article-title>
        <source>Alzheimers Dement</source>  
        <year>2007</year>  
        <month>07</month>  
        <volume>3</volume>  
        <issue>3</issue>  
        <fpage>217</fpage>  
        <lpage>26</lpage>  
        <pub-id pub-id-type="doi">10.1016/j.jalz.2007.04.388</pub-id>
        <pub-id pub-id-type="medline">19595941</pub-id>
        <pub-id pub-id-type="pii">S1552-5260(07)00483-9</pub-id></nlm-citation>
      </ref>
      <ref id="ref139">
        <label>139</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Mao</surname>
            <given-names>HF</given-names>
          </name>
          <name name-style="western">
            <surname>Chang</surname>
            <given-names>LH</given-names>
          </name>
          <name name-style="western">
            <surname>Yao</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Chen</surname>
            <given-names>WY</given-names>
          </name>
          <name name-style="western">
            <surname>Huang</surname>
            <given-names>WN</given-names>
          </name>
        </person-group>
        <article-title>Indicators of perceived useful dementia care assistive technology: caregivers' perspectives</article-title>
        <source>Geriatr Gerontol Int</source>  
        <year>2015</year>  
        <month>08</month>  
        <volume>15</volume>  
        <issue>8</issue>  
        <fpage>1049</fpage>  
        <lpage>57</lpage>  
        <pub-id pub-id-type="doi">10.1111/ggi.12398</pub-id>
        <pub-id pub-id-type="medline">25407039</pub-id></nlm-citation>
      </ref>
      <ref id="ref140">
        <label>140</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Martin</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Cunningham</surname>
            <given-names>C</given-names>
          </name>
        </person-group>
        <article-title>Ethical considerations for integrating technology</article-title>
        <source>Alzheimers care today</source>  
        <year>2007</year>  
        <volume>8</volume>  
        <issue>3</issue>  
        <fpage>251</fpage>  
        <lpage>8</lpage>  
        <pub-id pub-id-type="doi">10.1097/01.ALCAT.0000281873.66023.7e</pub-id></nlm-citation>
      </ref>
      <ref id="ref141">
        <label>141</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>McCabe</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Innes</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>Supporting safe walking for people with dementia: user participation in the development of new technology</article-title>
        <source>Gerontechnology</source>  
        <year>2013</year>  
        <volume>12</volume>  
        <issue>1</issue>  
        <fpage>4</fpage>  
        <lpage>15</lpage>  
        <pub-id pub-id-type="doi">10.4017/gt.2013.12.1.006.00</pub-id></nlm-citation>
      </ref>
      <ref id="ref142">
        <label>142</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>McKinstry</surname>
            <given-names>B</given-names>
          </name>
          <name name-style="western">
            <surname>Sheikh</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>The use of global positioning systems in promoting safer walking for people with dementia</article-title>
        <source>J Telemed Telecare</source>  
        <year>2013</year>  
        <month>07</month>  
        <volume>19</volume>  
        <issue>5</issue>  
        <fpage>288</fpage>  
        <lpage>92</lpage>  
        <pub-id pub-id-type="doi">10.1177/1357633X13495481</pub-id>
        <pub-id pub-id-type="medline">24163239</pub-id>
        <pub-id pub-id-type="pii">19/5/288</pub-id></nlm-citation>
      </ref>
      <ref id="ref143">
        <label>143</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Mehrabian</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Extra</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Wu</surname>
            <given-names>Y</given-names>
          </name>
          <name name-style="western">
            <surname>Pino</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Traykov</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Rigaud</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>The perceptions of cognitively impaired patients and their caregivers of a home telecare system</article-title>
        <source>Med Devices (Auckl)</source>  
        <year>2015</year>  
        <volume>8</volume>  
        <fpage>21</fpage>  
        <lpage>9</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://dx.doi.org/10.2147/MDER.S70520"/>
        </comment>  
        <pub-id pub-id-type="doi">10.2147/MDER.S70520</pub-id>
        <pub-id pub-id-type="medline">25552909</pub-id>
        <pub-id pub-id-type="pii">mder-8-021</pub-id>
        <pub-id pub-id-type="pmcid">PMC4277238</pub-id></nlm-citation>
      </ref>
      <ref id="ref144">
        <label>144</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Olsson</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Engström</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Skovdahl</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Lampic</surname>
            <given-names>C</given-names>
          </name>
        </person-group>
        <article-title>My, your and our needs for safety and security: relatives' reflections on using information and communication technology in dementia care</article-title>
        <source>Scand J Caring Sci</source>  
        <year>2012</year>  
        <month>03</month>  
        <volume>26</volume>  
        <issue>1</issue>  
        <fpage>104</fpage>  
        <lpage>12</lpage>  
        <pub-id pub-id-type="doi">10.1111/j.1471-6712.2011.00916.x</pub-id>
        <pub-id pub-id-type="medline">21843198</pub-id></nlm-citation>
      </ref>
      <ref id="ref145">
        <label>145</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Pino</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Boulay</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Jouen</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Rigaud</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>“Are we ready for robots that care for us?” Attitudes and opinions of older adults toward socially assistive robots</article-title>
        <source>Front Aging Neurosci</source>  
        <year>2015</year>  
        <volume>7</volume>  
        <fpage>141</fpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="https://dx.doi.org/10.3389/fnagi.2015.00141"/>
        </comment>  
        <pub-id pub-id-type="doi">10.3389/fnagi.2015.00141</pub-id>
        <pub-id pub-id-type="medline">26257646</pub-id>
        <pub-id pub-id-type="pmcid">PMC4512026</pub-id></nlm-citation>
      </ref>
      <ref id="ref146">
        <label>146</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Plastow</surname>
            <given-names>NA</given-names>
          </name>
        </person-group>
        <article-title>Is big brother watching you? Responding to tagging and tracking in Dementia care</article-title>
        <source>Br J Occup Ther</source>  
        <year>2006</year>  
        <month>11</month>  
        <day>01</day>  
        <volume>69</volume>  
        <issue>11</issue>  
        <fpage>525</fpage>  
        <lpage>527</lpage>  
        <pub-id pub-id-type="doi">10.1177/030802260606901106</pub-id></nlm-citation>
      </ref>
      <ref id="ref147">
        <label>147</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Robinson</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Hutchings</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Corner</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Beyer</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Dickinson</surname>
            <given-names>H</given-names>
          </name>
          <name name-style="western">
            <surname>Vanoli</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Finch</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Hughes</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Ballard</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>May</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Bond</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>A systematic literature review of the effectiveness of non-pharmacological interventions to prevent wandering in dementia and evaluation of the ethical implications and acceptability of their use</article-title>
        <source>Health Technol Assess</source>  
        <year>2006</year>  
        <month>08</month>  
        <volume>10</volume>  
        <issue>26</issue>  
        <fpage>iii, ix</fpage>  
        <lpage>108</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.journalslibrary.nihr.ac.uk/hta/volume-10/issue-26"/>
        </comment>  
        <pub-id pub-id-type="medline">16849002</pub-id>
        <pub-id pub-id-type="pii">03-16-04</pub-id></nlm-citation>
      </ref>
      <ref id="ref148">
        <label>148</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Robinson</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Hutchings</surname>
            <given-names>D</given-names>
          </name>
          <name name-style="western">
            <surname>Corner</surname>
            <given-names>L</given-names>
          </name>
          <name name-style="western">
            <surname>Finch</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Hughes</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Brittain</surname>
            <given-names>K</given-names>
          </name>
          <name name-style="western">
            <surname>Bond</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Balancing rights and risks: conflicting perspectives in the management of wandering in dementia</article-title>
        <source>Health Risk Soc</source>  
        <year>2007</year>  
        <month>10</month>  
        <day>16</day>  
        <volume>9</volume>  
        <issue>4</issue>  
        <fpage>389</fpage>  
        <lpage>406</lpage>  
        <pub-id pub-id-type="doi">10.1080/13698570701612774</pub-id></nlm-citation>
      </ref>
      <ref id="ref149">
        <label>149</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Siotia</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Simpson</surname>
            <given-names>C</given-names>
          </name>
        </person-group>
        <article-title>Applying telecare in dementia: what psychiatrists need to know</article-title>
        <source>Adv Psychiatr Treat</source>  
        <year>2008</year>  
        <month>09</month>  
        <day>01</day>  
        <volume>14</volume>  
        <issue>5</issue>  
        <fpage>382</fpage>  
        <lpage>388</lpage>  
        <pub-id pub-id-type="doi">10.1192/apt.bp.107.003566</pub-id></nlm-citation>
      </ref>
      <ref id="ref150">
        <label>150</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Sorell</surname>
            <given-names>T</given-names>
          </name>
          <name name-style="western">
            <surname>Draper</surname>
            <given-names>H</given-names>
          </name>
        </person-group>
        <article-title>Telecare, surveillance, and the welfare state</article-title>
        <source>Am J Bioeth</source>  
        <year>2012</year>  
        <volume>12</volume>  
        <issue>9</issue>  
        <fpage>36</fpage>  
        <lpage>44</lpage>  
        <pub-id pub-id-type="doi">10.1080/15265161.2012.699137</pub-id>
        <pub-id pub-id-type="medline">22881854</pub-id></nlm-citation>
      </ref>
      <ref id="ref151">
        <label>151</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Van Berlo</surname>
            <given-names>A</given-names>
          </name>
        </person-group>
        <article-title>Ethics in domotics</article-title>
        <source>Gerontechnology</source>  
        <year>2005</year>  
        <volume>3</volume>  
        <issue>3</issue>  
        <fpage>170</fpage>  
        <pub-id pub-id-type="doi">10.4017/gt.2005.03.03.007.00</pub-id></nlm-citation>
      </ref>
      <ref id="ref152">
        <label>152</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Welsh</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Hassiotis</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>O'Mahoney</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Deahl</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Big brother is watching you--the ethical implications of electronic surveillance measures in the elderly with dementia and in adults with learning difficulties</article-title>
        <source>Aging Ment Health</source>  
        <year>2003</year>  
        <month>09</month>  
        <volume>7</volume>  
        <issue>5</issue>  
        <fpage>372</fpage>  
        <lpage>5</lpage>  
        <pub-id pub-id-type="doi">10.1080/1360786031000150658</pub-id>
        <pub-id pub-id-type="medline">12959806</pub-id>
        <pub-id pub-id-type="pii">15VVQ366M0772CM0</pub-id></nlm-citation>
      </ref>
      <ref id="ref153">
        <label>153</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>White</surname>
            <given-names>EB</given-names>
          </name>
          <name name-style="western">
            <surname>Montgomery</surname>
            <given-names>P</given-names>
          </name>
        </person-group>
        <article-title>Electronic tracking for people with dementia: an exploratory study of the ethical issues experienced by carers in making decisions about usage</article-title>
        <source>Dementia</source>  
        <year>2014</year>  
        <month>03</month>  
        <day>01</day>  
        <volume>13</volume>  
        <issue>2</issue>  
        <fpage>216</fpage>  
        <lpage>32</lpage>  
        <pub-id pub-id-type="doi">10.1177/1471301212460445</pub-id>
        <pub-id pub-id-type="medline">24599815</pub-id>
        <pub-id pub-id-type="pii">1471301212460445</pub-id></nlm-citation>
      </ref>
      <ref id="ref154">
        <label>154</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Zwijsen</surname>
            <given-names>SA</given-names>
          </name>
          <name name-style="western">
            <surname>Niemeijer</surname>
            <given-names>A</given-names>
          </name>
          <name name-style="western">
            <surname>Hertogh</surname>
            <given-names>CM</given-names>
          </name>
        </person-group>
        <article-title>Ethics of using assistive technology in the care for community-dwelling elderly people: an overview of the literature</article-title>
        <source>Aging Ment Health</source>  
        <year>2011</year>  
        <month>05</month>  
        <volume>15</volume>  
        <issue>4</issue>  
        <fpage>419</fpage>  
        <lpage>27</lpage>  
        <pub-id pub-id-type="doi">10.1080/13607863.2010.543662</pub-id>
        <pub-id pub-id-type="medline">21500008</pub-id>
        <pub-id pub-id-type="pii">936414677</pub-id></nlm-citation>
      </ref>
      <ref id="ref155">
        <label>155</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Hughes</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Newby</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Louw</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Campbell</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>Hutton</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>Ethical issues and tagging in dementia: a survey</article-title>
        <source>J Ethics Ment Health</source>  
        <year>2008</year>  
        <volume>3</volume>  
        <issue>1</issue>  
        <fpage>1</fpage>  
        <lpage>6</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://eprint.ncl.ac.uk/file_store/production/38622/6E77A092-E301-414B-8F6B-B1C901E2A634.pdf"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref156">
        <label>156</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Marshall</surname>
            <given-names>M</given-names>
          </name>
        </person-group>
        <article-title>Technology to help people with dementia remain in their own homes</article-title>
        <source>Generations</source>  
        <year>1999</year>  
        <volume>23</volume>  
        <issue>3</issue>  
        <fpage>85</fpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://connection.ebscohost.com/c/articles/2517954/technology-help-people-dementia-remain-their-own-homes"/>
        </comment> </nlm-citation>
      </ref>
      <ref id="ref157">
        <label>157</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Werner</surname>
            <given-names>S</given-names>
          </name>
          <name name-style="western">
            <surname>Landau</surname>
            <given-names>R</given-names>
          </name>
        </person-group>
        <article-title>Social workers' and students' attitudes toward electronic tracking of people with Alzheimer's disease</article-title>
        <source>J Soc Work Educ</source>  
        <year>2011</year>  
        <month>08</month>  
        <volume>30</volume>  
        <issue>5</issue>  
        <fpage>541</fpage>  
        <lpage>57</lpage>  
        <pub-id pub-id-type="doi">10.1080/02615479.2010.508090</pub-id></nlm-citation>
      </ref>
      <ref id="ref158">
        <label>158</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Frisardi</surname>
            <given-names>V</given-names>
          </name>
          <name name-style="western">
            <surname>Imbimbo</surname>
            <given-names>B</given-names>
          </name>
        </person-group>
        <article-title>Gerontechnology for demented patients: smart homes for smart aging</article-title>
        <source>J Alzheimers Dis</source>  
        <year>2011</year>  
        <volume>23</volume>  
        <issue>1</issue>  
        <fpage>143</fpage>  
        <lpage>6</lpage>  
        <pub-id pub-id-type="doi">10.3233/JAD-2010-101599</pub-id>
        <pub-id pub-id-type="medline">21157023</pub-id>
        <pub-id pub-id-type="pii">W881X62287U02867</pub-id></nlm-citation>
      </ref>
      <ref id="ref159">
        <label>159</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Kearns</surname>
            <given-names>WD</given-names>
          </name>
          <name name-style="western">
            <surname>Fozard</surname>
            <given-names>J</given-names>
          </name>
        </person-group>
        <article-title>High-speed networking and embedded gerontechnologies</article-title>
        <source>Gerontechnology</source>  
        <year>2007</year>  
        <volume>6</volume>  
        <issue>3</issue>  
        <fpage>135</fpage>  
        <lpage>46</lpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://gerontechnology.info/index.php/journal/article/view/702"/>
        </comment>  
        <pub-id pub-id-type="doi">10.4017/gt.2007.06.03.003.00</pub-id></nlm-citation>
      </ref>
      <ref id="ref160">
        <label>160</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Joddrell</surname>
            <given-names>P</given-names>
          </name>
          <name name-style="western">
            <surname>Astell</surname>
            <given-names>AJ</given-names>
          </name>
        </person-group>
        <article-title>Studies involving people with dementia and touchscreen technology: a literature review</article-title>
        <source>JMIR Rehabil Assist Technol</source>  
        <year>2016</year>  
        <month>11</month>  
        <day>04</day>  
        <volume>3</volume>  
        <issue>2</issue>  
        <fpage>e10</fpage>  
        <pub-id pub-id-type="doi">10.2196/rehab.5788</pub-id></nlm-citation>
      </ref>
      <ref id="ref161">
        <label>161</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Peterson</surname>
            <given-names>C</given-names>
          </name>
          <name name-style="western">
            <surname>Prasad</surname>
            <given-names>NR</given-names>
          </name>
          <name name-style="western">
            <surname>Prasad</surname>
            <given-names>R</given-names>
          </name>
        </person-group>
        <article-title>The future of assistive technologies for dementia</article-title>
        <source>Gerontechnology</source>  
        <year>2012</year>  
        <volume>11</volume>  
        <issue>2</issue>  
        <fpage>195</fpage>  
        <comment>
          <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://gerontechnology.info/index.php/journal/article/view/gt.2012.11.02.427.00"/>
        </comment>  
        <pub-id pub-id-type="doi">10.4017/gt.2012.11.02.427.00</pub-id></nlm-citation>
      </ref>
      <ref id="ref162">
        <label>162</label>
        <nlm-citation citation-type="web">
        <source>The Association for Geographic Information</source>  
        <year>2015</year>  
        <access-date>2016-10-16</access-date>
        <comment>AGI Foresight Report 2020 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.agi.org.uk/news/foresight-report">http://www.agi.org.uk/news/foresight-report</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHnUjB16"/></comment> </nlm-citation>
      </ref>
      <ref id="ref163">
        <label>163</label>
        <nlm-citation citation-type="journal">
        <person-group person-group-type="author">
          <name name-style="western">
            <surname>Moniz-Cook</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Vernooij-Dassen</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Woods</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>Verhey</surname>
            <given-names>F</given-names>
          </name>
          <name name-style="western">
            <surname>Chattat</surname>
            <given-names>R</given-names>
          </name>
          <name name-style="western">
            <surname>De Vugt</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Mountain</surname>
            <given-names>G</given-names>
          </name>
          <name name-style="western">
            <surname>O'Connell</surname>
            <given-names>M</given-names>
          </name>
          <name name-style="western">
            <surname>Harrison</surname>
            <given-names>J</given-names>
          </name>
          <name name-style="western">
            <surname>Vasse</surname>
            <given-names>E</given-names>
          </name>
          <name name-style="western">
            <surname>Dröes</surname>
            <given-names>RM</given-names>
          </name>
          <name name-style="western">
            <surname>Orrell</surname>
            <given-names>M</given-names>
          </name>
          <collab>INTERDEM group</collab>
        </person-group>
        <article-title>A European consensus on outcome measures for psychosocial intervention research in dementia care</article-title>
        <source>Aging Ment Health</source>  
        <year>2008</year>  
        <month>01</month>  
        <volume>12</volume>  
        <issue>1</issue>  
        <fpage>14</fpage>  
        <lpage>29</lpage>  
        <pub-id pub-id-type="doi">10.1080/13607860801919850</pub-id>
        <pub-id pub-id-type="medline">18297476</pub-id>
        <pub-id pub-id-type="pii">790802368</pub-id></nlm-citation>
      </ref>
      <ref id="ref164">
        <label>164</label>
        <nlm-citation citation-type="web">
        <source>Alzheimer Europe</source>  
        <year>2012</year>  
        <access-date>2016-10-16</access-date>
        <comment>2010: The ethical issues linked to the use of assistive technology in dementia care 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.alzheimer-europe.org/EN/Ethics/Ethical-issues-in-practice/2010-The-ethical-issues-linked-to-the-use-of-assistive-technology-in-dementia-care">http://www.alzheimer-europe.org/EN/Ethics/Ethical-issues-in-practice/2010-The-ethical-issues-linked-to-the-use-of-assistive-technology-in-dementia-care</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6lHndGoHE"/></comment> </nlm-citation>
      </ref>
      <ref id="ref165">
        <label>165</label>
        <nlm-citation citation-type="web">
        <source>Alzheimer Europe</source>  
        <year>2014</year>  
        <access-date>2016-12-28</access-date>
        <publisher-loc>Luxembourg</publisher-loc>
        <publisher-name>Alzheimer Europe</publisher-name>
        <comment>Ethical dilemmas faced by carers and people with dementia 
        <ext-link xmlns:xlink="http://www.w3.org/1999/xlink" xlink:type="simple" xlink:href="http://www.alzheimer-europe.org/Publications/Alzheimer-Europe-Reports">http://www.alzheimer-europe.org/Publications/Alzheimer-Europe-Reports</ext-link>
        <ext-link ext-link-type="webcite" xlink:href="6n7AIGmAe"/></comment> </nlm-citation>
      </ref>
    </ref-list>
  </back>
</article>
